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RheumNow Podcast – Driving in Pain (8.20.2021)

d Jack Cush, MD

You know, I'm a very good driver. We all think we're great drivers - but consider what it's like to drive in pain: would you be a good driver? Also, I want you to consider the diagnosis of calcium pyrophosphate dihydrate disease (CPPD). But first, let's look at a study out of Scotland, looking at military service and greater risk of hip and knee replacement.

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Oligoarticular vs. Polyarticular Psoriatic Arthritis

d Jack Cush, MD

A psoriatic arthritis (PsA) cohort analysis reveals many similarities and few distinctions between those who present with oligoarticular and polyarticular PsA.

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vaccine,mRNA,Covid,vial

Sustained Effectiveness of mRNA Vaccines Against COVID-19 Hospitalizations

d MMWR

The CDC has reported that mRNA vaccine effectiveness against COVID-19–associated hospitalizations was sustained over 24 weeks; but there is evidence of waning protection amongst the immunosuppressed.

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EULAR Points on Managing Difficult Rheumatoid Arthritis

d Jack Cush, MD

A EULAR task force has promulgated several points to consider in managing difficult-to-treat RA. These "points" are unique in directing the rheumatologist's attention to the potential for misdiagnosis and the impact of comorbid conditions on what is perceived as poorly controlled RA.

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COVID,vaccinate,injection,green

HHS, FDA & CDC Joint Recommendation on COVID Booster

d FDA

Today, public health and medical experts from the U.S. Department of Health and Human Services (HHS) released the following statement on the Administration’s plan for COVID-19 booster shots for the American people.

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Tocilizumab in Refractory Skin and Joint Scleroderma

d Jack Cush, MD

The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic sclerosis (SSc)  and was shown to be effective in refractory joint and skin disease with good long-term retention rates and disease stabilization.

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Inflammatory Arthritis Impairs Male Fertility

d Jack Cush, MD

A new study in Annals of Rheumatic Disease shows that inflammatory arthritis (IA) may impair male fertility, especially during the peak reproductive age when lower fertility rates, higher childlessness rates and more fertility problems were seen.

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US News & World Report Ranks Best Rheumatology Hospitals https://t.co/DgoE0On7So https://t.co/jkJcOGlJXo

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Dr. John Cush RheumNow ( View Tweet)
In case you missed it— Booster Shots for Rheumatology Patients on Immunosuppressive Medications https://t.co/dIzrv3B12u https://t.co/2x63osTNHh

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Dr. John Cush RheumNow ( View Tweet)
We all think we're great drivers - but consider what it's like to drive in pain: would you be a good driver? That and more on this weeks podcast. Download now. https://t.co/dbX9RN8ji5 https://t.co/27DnNPbyFj

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Dr. John Cush RheumNow ( View Tweet)
Treatment of RA may be difficult, as it is estimated that up to 10% of patients meet the EULAR definition of difficult-to-treat rheumatoid arthritis (D2T RA). Now a EULAR task force has promulgated several points to consider (PtCs) in managing D2T RA. https://t.co/w4EWHD3RC4 https://t.co/s4q7jpitC8

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Dr. John Cush RheumNow ( View Tweet)
HHS, FDA & CDC Joint Recommendation on COVID Booster https://t.co/pKlFjnlQeu https://t.co/ue0pMfEvfm

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Dr. John Cush RheumNow ( View Tweet)
Acupuncture (AP) studied in 440 men w/ chronic prostatitis/chronic pelvic pain syndrome (AP vs Sham). Responders were higher in the AP group at wk 8 and week 32 (61.5% vs 38.3%; adjusted odds ratio, 2.6) https://t.co/TOtUBE3Wvu

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Dr. John Cush RheumNow ( View Tweet)

RCT showing Midodrine is effective in treating Vasovagal Syncope. 133 pts with hx of median of 6 syncope episodes in the prior year; given MID or PBO. After 12 mos, MID had less syncope episodes (42% vs. 61% PBO; RR=0.69) https://t.co/5pCSaYB76m

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Dr. John Cush RheumNow ( View Tweet)

https://t.co/wM1iRxtHvk The interleukin-6 inhibitor, tocilizumab (TCZ), was studied in a cohort of difficult systemic sclerosis (SSc) and was shown to be effective in refractory joint and skin disease with good long-term retention rates and disease stabilization. https://t.co/1suUabDGhL

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Dr. John Cush RheumNow ( View Tweet)
Free Video from the NEJM - Mobility Assessment in Older Adults. Useful in assessing geriatric patients, frailty, risk of falls (4 stage balance test) and functional impairment. 7:36 long. https://t.co/zZcDDOg12U

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Dr. John Cush RheumNow ( View Tweet)

Belimumab in Pregnancy? a study of 13 pregnancies in 13 pts, mean age 38 yrs.. There were 11 live births, 1 case omphalitis (recovered w Abx) . No fetal anomalies found. 6 pts (46%) w/ Hx of recurrent pregnancy loss, four had live births on BEL https://t.co/FJJhepa25M

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Dr. John Cush RheumNow ( View Tweet)

Acute CPPD arthritis -1697 pts compared w/ 6503 controls. CPPD pts were older (74 yrs), 57% female, 81% White; & assoc w/ OA (OR 3.1), male (OR 1.3), RA (2.1), gout (2.8), PPI (1.9), diuretics (~1.5). CPPD less likely in Blacks vs Whites (OR 0.47) https://t.co/U22jBmjWXm

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Dr. John Cush RheumNow ( View Tweet)

#RA & Driving studied w/ installed auto sensor-based instrumentation - 23 controls compared to 33 RA pts (1292 driving hrs): shows RA & worsening Dz severity assoc w/ poor vehicle control; Braking/accelerating & steering variability liked to CDAI levels. https://t.co/umXGAbuicz https://t.co/oN2tTXpAtE

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Dr. John Cush RheumNow ( View Tweet)
Spirometry study in 2,008 #RA patients - compared to controls, RA has a higher risk of restrictive Lung dz (OR 1.36, 95%CI 1.21,1.52) and obstructive LD (OR 1.21, 95%CI 1.07,1.37) independent of confounders like smoking https://t.co/UWViAZL6PO https://t.co/9OBz5ROKhw

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Dr. John Cush RheumNow ( View Tweet)
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