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Safety of Paternal DMARD or Biologic Use

d Jack Cush, MD

A large cohort study of expectant fathers treated for immune-mediated inflammatory diseases (IMIDs) failed to show any detrimental effect from paternal exposure to immunosuppressive or biologic agents on offspring outcomes.

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RECIPE Trial - Mycophenolate to Suppress Immunogenicity with Pegloticase in Gout

d Jack Cush, MD

Pegloticase is indicated in the treatment of severe gout patients but prolonged use may be limited by immunogenicity to the PEG moiety. A randomized, controlled trial has shown that concomitant mycophenolate mofetil (MMF) may prolong the efficacy of pegloticase in gout.

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Liver Management in Rheumatoid Arthritis - RNL2021 Highlight

d Olga Petryna, MD

While rheumatoid arthritis (RA) is not known to affect the liver directly, underlying liver disease and treatment-related effects on the liver can often become an obstacle in the management of many RA patients. In his Sunday presentation at RNL2021, Dr.

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Survey of 500 pts with systemic rheumatic diseases during the COVID-19 pandemic showed few who discontinuations Rx - 2.2% D/C for fear of immunosuppression; 3.8% for shortages (mostly HCQ); 2.6%) for resp infx and 6% for side-effects. https://t.co/2BJIYeBSIu

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Dr. John Cush RheumNow ( View Tweet)

Dr. Buch discusses the differences between difficult to treat vs refractory RA in #RNL2021. @RheumNow https://t.co/TqrHcBt0la
Dr. Rachel Tate uptoTate ( View Tweet)
"Over-achievers aren't OK with mediocrity"..."best to surround yourself with overachievers" - Joe Judge

Dr. John Cush RheumNow ( View Tweet)

Want to ask a question for the RheumNow Podcast? Record your question in 1 minute or less and we may feature it on an upcoming episode. https://t.co/hOWU67uY1Y https://t.co/ooph09KuL9

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Dr. John Cush RheumNow ( View Tweet)
News Feature: Rituximab vs. JAK inhibitors in Rheumatoid Lung Disease https://t.co/2P0tdxvZD2 https://t.co/7gfE1CPSEx

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Dr. John Cush RheumNow ( View Tweet)
Thanks to everyone who attended RheumNow Live 2021 in person and virtually! WE hope you enjoyed and learned from it. #RNL2021

Dr. John Cush RheumNow ( View Tweet)

Early RA pts given steroids (GC) do Not have short or long term benefits from GCs. 180 ERA pts given compared to 294 who did not. 5 yr F/U showed no differences in DAS28-CRP, HAQ or pain between groups. Steroids were used more in seronegative RA. https://t.co/CDUKDgsLRa

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Dr. John Cush RheumNow ( View Tweet)

Using both glucocorticoids & PPI leads to additive risk of osteoporotic fractures - UK database studiedd 12351 RA pts - 1411 w/ OP Fx. Concomitant GCs + PPIs assoc w/ 1.6-fold risk of OP Fx (adj HR: 1.60) vs nonuse; more than 1.2-fold risk w/ either alone https://t.co/vvA6P5LEgs

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Dr. John Cush RheumNow ( View Tweet)

We just started our last faculty panel on RA with audience Q&A. #RNL2021 https://t.co/o1s2asdLcS
Dr. John Cush RheumNow ( View Tweet)
Mavrilimumab (anti-GM-CSF) metanalysis shows gret benefit in #RA - 1145 pts, 3 trials shows significant 12 week responses by: 1) DAS28-CRP remission (RR = 3.31); 2) ACR20 (RR = 2.38); 3) ACR50 (RR = 2.93) & 4) ACR70 (RR = 4.9). Where is it? https://t.co/9L5PFEB1DI

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Dr. John Cush RheumNow ( View Tweet)

Spondyloarthritis faculty panel with audience Q&A #RNL2021 https://t.co/iSosAtHLCZ
Dr. John Cush RheumNow ( View Tweet)
Follow the hashtag #RNL2021 for all RheumNow Live coverage today!

Dr. John Cush RheumNow ( View Tweet)

Dr. Artie Kavanaugh leading the spondyloarthritis pod focusing on enthesitis and dactylitis management. #RNL2021 https://t.co/NCUwabTXVd
Dr. John Cush RheumNow ( View Tweet)
Join me at the @RheumNow SpA session happening now! #rheumatology #spondyloarthritis #ankylosing https://t.co/CTLq0xWQys
Nigil Haroon MD, PhD 💎🦜🌎🩺🔬 NigilHaroon ( View Tweet)
Leading the Rheumatoid Arthritis pod with discussions on pneumonia and RA and interstitial lung disease in RA. #RNL2021 https://t.co/psxMTHsOva
Dr. John Cush RheumNow ( View Tweet)
New podcast available! Dr. Jack Cush rants on the journal reports, news and FDA actions featured this past week on RheumNow. https://t.co/rPnLp2NfRq https://t.co/TSTP2tWxXy

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Dr. John Cush RheumNow ( View Tweet)
Our in-person participants engaging with the psoriatic panel #RNL2021 https://t.co/N0Cdos3Rhb
Dr. John Cush RheumNow ( View Tweet)
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