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This week's Tuesday Night Rheumatology, hosted by Dr. Jack Cush, featured highlights from the 2022 RheumNow Live Rheumatoid Arthritis - Best Management Pod, followed by a lively audience Q & A. Lectures featured:
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Dr. Jack Cush reviews the news, regulatory updates and journal reports from the past week on RheumNow.com. This week gout worries, mortality risks, measuring anti-drug antibodies and a better way in lupus?
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The cardiovascular (CV) risks of inflammation and gout are well known, but until recently hasn't been tied to calcium pyrophosphate deposition (CPPD) disease. A recent EHR study shows that acute CPPD crystal arthritis was significantly associated with elevated risks for non-fatal CV events.
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A large US population based study shows that psoriasis is associated with a higher risk of nonalcoholic fatty liver disease (NAFLD).
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JAMA reports that despite NIH recommendations (that corticosteroids only be used in hospitalized COVID-19 patients), nonhospitalized COVID infected patients were oftent prescribed systemic corticosteroids.
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People with gout appeared less likely to develop dementia than age- and sex-matched peers, a database study from Korea found.
Dr. John Cush
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Long COVID Manifestations
The acute consequences of a SARS-CoV-2 infection may be bothersome or devastating, but the long-term consequences may lead to so-called "long COVID" syndrome. Long COVID appears to affect up to 20% of those who survive COVID-19.
https://t.co/BFgazzEQWl https://t.co/0HyWZ3HcLG
Dr. John Cush
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Novel patient self-drawn capillary (CAP) tube blood testing for CRP/RF/CCP - YES, Pt does this at home! 49/50 seropos.RA pts successfully collected samples; , correlations w/ venous blood=excellent: CRP (0.992), CCP (0.984), RF (0.994) https://t.co/zLiwEpiyi9
Conclusions
Dr. John Cush
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Watch: Treatment Choices in Refractory RA
Dr. Cush presents Treatment Choices in Refractory RA, during the RheumNow Live 2022 meeting held in March 2022. #MedEd
https://t.co/5wjLyVAS7o https://t.co/dnh8Y5Of4G
Dr. John Cush
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UK experience with 7 cases of monkeypox. Common sxs=fever, rash, HA, lymphadenopathy, LFTs. Complications =pneumonitis, encephalitis, keratitis, bacterial infx. Often skin lesions, abscesses https://t.co/OW3VMtGTGD https://t.co/yTKODreXYg
Dr. John Cush
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To TDM or Not in Rheumatology?
Therapeutic Drug Monitoring (TDM), especially for biologic therapies, has become a standard in gastroenterology, but shunned by most rheumatologists. But now, EULAR has a recommendation...
https://t.co/u86Vd8bFGr
#MedEdTwitter https://t.co/IpKqPoWM9R
Dr. John Cush
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Watch: Adherence to Rheumatoid Therapies
Dr. Michaud presents Adherence to Rheumatoid Therapies at the RheumNow Live 2022 meeting held in March. #MedEd
https://t.co/sCCnx82ptN https://t.co/GJE0Ktwm7B
Dr. John Cush
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Visit @RheumNow podcast channel & hear experts from the #SLEEducatorsNetwork review a new framework for defining disease modification in SLE and why there’s a need to consider therapies that modify the immunologic mechanisms of SLE. Sponsored by GSK USMA https://t.co/6HiO63Rthd https://t.co/7rjgj1WqGj
Dr. John Cush
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Watch: Juvenile Spondyloarthritis
Dr. Pamela Weiss demystifies juvenial SpA and discusses the unique aspects of the disease.
https://t.co/xa2mO0fdzq
#MedEd https://t.co/6JVUGRx5Go
Dr. John Cush
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1049 non-diabetic hospitalized gout pts (2014 -2020); saw an inverse relationship betw CKD & NAFLD, & increaseing negative associations w/ NAFLD severity (mild OR 0.392; Mod: 0.379; Severe 0.148). NAFLD negatively assoc w/ CKD risk in gout https://t.co/5fuIiO1LwM https://t.co/Jp8CjWkn5m
Dr. John Cush
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NEJM : 40 yoM 2 wk hx scaly foot rash, joint swelling & LBP. 1 wk ago had diarrhea & urethral discharge. Feet show keratoderma blenorrhagicum; PSO on scalp, trunk, hands, nail changes, +swollen joints, CRP 59/L, UA sterile pyuria, B27+ https://t.co/GgKWIbL9Br https://t.co/m0fbg8mJUc
Laurent ARNAUD
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🆒 Current indications for #biologics, in inflammatory rheumatic diseases 🔎 such as rheumatoid #arthritis, axSPA, PsA etc... A useful checklist ✅ to keep in the pocket prepared with
@DocFelten #Rheumatology #EULAR2022 https://t.co/cfc4VaF6GZ
Dr. John Cush
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A Roadmap for Investigating Preclinical Autoimmunity Using Patient-Oriented and Epidemiologic Study Designs: Example of Rheumatoid Arthritis - a comprehensive overview of studies of preclinical RA and risk of RA https://t.co/DKbDXkvFyQ
Meral K. El Ramahi, MD
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@ERheumat @mukes_dr @drMsayan @vikasagrIMMUNO @DurgaPrasannaM1 @LatikaGupta_ @Janetbirdope @AshimaMakol @sclerodermaUM @PanktiMehta24 @ACR_Journals Sclerotylosis… Huriez Syndrome?
Triad of 1) sclerodactyly 2) palmoplantar keratoderma 3) nail changes. High susceptibility of early onset squamous cell cancer of affected areas
Dr. John Cush
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Study of 100 pts w/ gouty arthritis, 51% had hypertension, nearly half insufficiently controlled. Undiagnosed HTN was seen in 18%. Gouty pts w/ HTN frequently (92%) had serum uric acid levels above the target https://t.co/jc0UGyrK2B https://t.co/kDD2KfQd3K
