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Perform (annual) skin exams in patients in MTX based on discovery of a new adverse effect signal with use of low dose MTX (median dose 15 mg/wk) with a NNH of 167! Screening 160 RA patients on MTX will identify 1 skin Ca. Amazing #ACR20 Year in Review by @JYazdanyMD. @RheumNow https://t.co/hUCzKSYZnB
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
*When will we have a vaccine?
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
“When we will have a vaccine. The answer is not so simple. Safety [of vaccines] is an important component of making a decision to move forward.”- Dr. Eric Rubin at #ACR20.
We want a vaccine that is both SAFE and EFFECTIVE! @RheumNow
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Abst#0142 at #ACR20, a post-hoc analysis of FINCH2, shows that filgotinib (FIL)(Jak1-i) + csDMARD improved the degree of activity impairment in a clinically relevant manner compared to placebo + csDMARD in pts w/ inadequate response to bDMARD . @RheumNow https://t.co/6M42LUVuht
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Great #rheumtwearls #ACR20 https://t.co/HzKkhnArvr
Marissa Blum blum_marissa ( View Tweet)
ACPA in patients with RA are multireactive. How can one antibody bind to so many proteins? ACPA recognize very small linear epitopes shared by many posttranslationally modified proteins.
2F012. Antibodies in RA. #ACR20. <TK https://t.co/OUqshFoxSb
ARD & RMD Open ARD_BMJ ( View Tweet)
Year in review @JYazdanyMD take home points from 2 key positive trials (finally!) in SLE this year #ACR20 @RheumNow https://t.co/74SVwNavPK
Richard Conway RichardPAConway ( View Tweet)
#ACR20 Year in Review @JYazdanyMD presenting PEXIVAS results. The proof of efficacy equivalence and safety superiority for the low dose steroid arm is a game-changer @rheumnow https://t.co/bJ1WLL71sB
Richard Conway RichardPAConway ( View Tweet)
Who will be more likely to have chronic reactive arthritis @RheumNow #ACR20 @CRASCRRheum
Janet Pope Janetbirdope ( View Tweet)
IL-6 blockade for management of irAEs without inhibiting anti cancer immune response. Should these be given prior or concomitantly with ICIs? Some interesting ideas to look up from the cancer and immunotherapy study group. #ACR20 @UTSWNews @ACRheum @RheumNow
Adela Castro AdelaCastro222 ( View Tweet)
#ACR20 Abstr#0433 #PlenaryACR Georgia SLE registry 336 pts ⬆️stroke/isch heart dz with:
👉3X stroke risk and 24X IHD risk for black pts
👉predictors stroke: black race, DLE, renal dz
👉predictors IHD: age>65, black race, neuro & immuno d/o (e.g, APAs)
@RheumNow https://t.co/u6Ky7r0FYF
k dao KDAO2011 ( View Tweet)
Plenary session 1 no#2F011 #ACR20 @rheumnow
Black #SLE patients have a 3 fold higher stroke and 24 fold higher Ishemic Heart Disease risk! https://t.co/AYtiXk7pDa
Bella Mehta bella_mehta ( View Tweet)
Tech support during #ACR 20 per below if needed! @RheumNow https://t.co/6OIvJDJReq
Meral K. El Ramahi, MD MeralElRamahiMD ( View Tweet)
Environmental and geographical factors matter! @rheumnow #ACR20 https://t.co/uq8236Dv5r
Bella Mehta bella_mehta ( View Tweet)
Dr. L Calabrese excellent review of irAEs and a proposed personalized algorithm for mgmt of irAE #ACR20 @LCalabreseDO @rheumnow
He believes there should be more studies combining TNFi or IL-6 with CPI https://t.co/GbvgXtNJnI
k dao KDAO2011 ( View Tweet)
Looking forward to learning lots in the next 20mins on how to approach #telemedicine to provide better care for our patients.
Important to remember to keep patients at the centre of our priorities.
#rheumtwitter
Session 2F05 #ACR20 @RheumNow https://t.co/aBrnytCWpu
Mrinalini Dey DrMiniDey ( View Tweet)
Behind the scenes at our #irae “study group” @NohaMDAnderson @LCalabreseDO #ACR20 #Immunotherapy https://t.co/eE7E7Qi1Zq
Cassandra Calabrese CCalabreseDO ( View Tweet)
Dr. Noha Abdel-wahab on timing for grade 3/4 irAE fastest with the skin after exposure to CPI #ACR20 @rheumnow https://t.co/sc5c6Zn3Uq
k dao KDAO2011 ( View Tweet)
#hydroxychloroquine is not a ‘cutie’ drug. E Park et al showed that HCQ does not increase QT interval in RA & SLE patients including if on other meds that may affect QT but known heart disease excluded from study #ACR20 #ACR2020 @RheumNow abstr#432 @CRASCRRheum https://t.co/FGVPknmj5q
Janet Pope Janetbirdope ( View Tweet)
#ACR20 Break time - go take a hike OR go ride a bike!
https://t.co/rYW3p4OgE3
Links:
Dr. John Cush RheumNow ( View Tweet)