It has been long known that rheumatoid arthritis is associated with an increased mortality rate, especially in seropositive patients and those with extraarticular manifestations. With the advent of new RA associated autoantibodies, Ajegenova et al studied the effects of different autoantibodies on mortality and cause of mortality.
Following is a list of top tweets in September and October 2016; they were selected based on the number of clicks, retweets and likes by the viewership. More than 40,000 people were reached with the first one on our list.
Low back pain (LBP) is the fifth most common reason for all physician visits in the United States and nearly 25% of all U.S. adults have had LBP in the last 3 months and nearly 6% reported at least 1 episode of severe acute low back pain in the last 1-year.
Low back pain (LBP) is a highly prevalent public health problem. Not surprisingly, imaging of LBP is also an expensive and often overused diagnostic tool.
Researchers from the Department of Veterans Affairs (VA) sought to define the problem and formulate recommendations to avoid ordering imaging tests for nonspecific LBP.
The current JAMA Pediatrics issue has published a report showing that adjunctive corticosteroid therapy yielded significantly fewer coronary artery complications compared with intravenous immunoglobulin therapy alone, particularly among high-risk patients with Kawasaki disease.
Dr. Cush Reviews Highlights from the past week on RheumNow.com. Register to receive free daily rheumatology news written by rheumatologists for rheumatologists. Download the podcast at iTunes.com.
Most women with systemic lupus erythematosus (SLE) have no or little disease activity during pregnancy, but experience greater disease activity or overt flares during the first year postpartum, a Norwegian study has found.
Everything will be alright in the end; and if it’s not alright, then it’s not yet the end.
– Suni Kapoor (from the Best Exotic Marigold Hotel)
The Washington Post recently interviewed Dr. Eliza Chakavarty of the OMRF about the evolution in attitudes and outcomes of lupus women who wish to get pregnant.
Better understanding of the interplay between lupus activity and pregnancy outcomes, along with better medication, allows the discussion between hopeful patients and planful rheumatologists to be constructive ones.
The results of the Nor-Switch study were presented at the United European Gastroenterology annual congress this week demonstrating no significant difference in effect, adverse effects or antibody formation in patients switched from Remicade to the biosimilar infliximab (CT-P13, Remsima). Outcomes were compared to those who continued to take IV Remicade.
Researchers from the University of British Columbia reported on their systematic review and meta-analysis of risk of herpes zoster (HZ) in patients receiving biologics, DMARDs and/or corticosteroids for autoimmune diseases.
Pfizer has announced it will ship its new FDA-approved biosimilar, Inflectra, in late November and that it will be priced at a15 percent discount to current wholesale prices.Inflecta's generic name is infliximab-dyyb. This same agent is already available in Europe. This would be the first biosimilar TNF inhibitor to become available in the United States.
This is written as a check-up to your digital self and a wake-up call to those of you who are disconnected lazily or willfully. This is written for the journal-subscribing, big textbook toting physicians whose primary education is acquired at the medical library, weekly medical conferences or grandiose annual conventions. Before you bail out on this blog, you should recognize the consequences of not being digital.
A Lancet meta-analysis has reviewed the preventative effects of low-molecular-weight heparin (LMWH) on placenta-mediated pregnancy complications include pre-eclampsia, late pregnancy loss, placental abruption, and birth of a small-for-gestational-age (SGA) neonate.Because of significant heterogeneity in past trial results, they performed an individual patient data meta-analysis.
