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Post-Arthroscopic Increase in Septic Arthritis

Sep 27, 2021

A longitudinal study from Iceland shows an increasing number of native joint infections (NJI), with iatrogenic, postarthroscopic infections being of particular concern.



Between 2003-2017 they identified 299 NJI (40 children and 259 adults) with more infections in men (33% women vs 67

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RheumNow Podcast – High Science and Future Treatments (9.10.2021)

Sep 10, 2021

This week: high science that affect future treatments; breakthrough infections in our patients, and what's up with that; and soon your radiologist is going to be replaced by AI. This and more in our review of the news and journal articles from the past week.

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MMP13 is one of several key contributors to #OA. Novel research showing the IA depot of nanoparticles w/ small interfering RNAs targeting MMP13 (breaks down type II collagen) can reduce cartilage damage/loss in mouse model of post-traumatic OA https://t.co/3wy6Bdk4o0

Dr. John Cush @RheumNow( View Tweet )

Sep 10, 2021
FDA has issued 510(k) (medical device) clearance for the marketing of an artificial intelligence algorithm from Radiobotics to diagnose #OA knee - "RBknee™" can identify osteophytes, subchondral sclerosis, joint space narrowing & width https://t.co/cY111NH69w

Dr. John Cush @RheumNow( View Tweet )

Sep 08, 2021

RheumNow Podcast – Driving in Pain (8.20.2021)

Aug 20, 2021

You know, I'm a very good driver. We all think we're great drivers - but consider what it's like to drive in pain: would you be a good driver? Also, I want you to consider the diagnosis of calcium pyrophosphate dihydrate disease (CPPD). But first, let's look at a study out of Scotland, looking

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Osteoarthritis vs. Rheumatoid Arthritis https://t.co/qvVEcKqNAM https://t.co/WDyIZxoL7v
Dr. John Cush @RheumNow( View Tweet )
Aug 16, 2021

Lumbar Spine Decompression Alone is Superior to Decompression with Fusion

Aug 05, 2021

The NEJM has published a multicenter study wherein patients with surgical lumbar spinal stenosis and degenerative spondylolisthesis were found to fair equally well (noninferior if treated with decompression surgery alone compared to decompression with instrumented fusion.

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RheumNow Podcast – Psoriatic Arthritis Without Psoriasis (7.30.2021)

Jul 30, 2021

How much psoriasis do you need to have in order to have psoriatic arthritis? This plus a review of rheumatology and COVID news from the past week on RheumNow.com.

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Rheumatoid Poor Outcomes Not Linked to Comorbidity

Jul 26, 2021

Disease activity leads to poor outcomes; but does comorbidity add to this?  A recent analysis suggests that while comorbidities do not affect long-term, functional outcomes, sociodemographic factors do affect outcomes in rheumatoid Arthritis (RA).

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ICYMI: Metanalysis of Tramadol efficacy & safety in knee or hip #OA. 6 RCTs (3,611 pts) showed little clinical benefit w/ 100/d or 200 mg/d; only 300mg/d was better vs PBO at pain & functional improvement. All doses had higher risk of GI, CNS AEs & W/D https://t.co/wDLHFQWFOe https://t.co/l4B83eUQrW
Dr. John Cush @RheumNow( View Tweet )
Jul 25, 2021
Metanalysis of Tramadol efficacy & safety in knee or hip #OA. 6 RCTs (3,611 pts) showed little clinical benefit w/ 100/d or 200 mg/d; only 300mg/d was better vs PBO at pain & functional improvement. All doses had higher risk of GI, CNS AEs & W/D https://t.co/wDLHFQWFOe

Dr. John Cush @RheumNow( View Tweet )

Jul 22, 2021

Growing Cannabis Use in Arthritis Patients

Jul 21, 2021

The National Databank for Rheumatic Diseases reports a significant increased in cannabis use amongst arthritis patients between 2014-2019, suggesting patients are more frequently engaged in self-management of pain and the unmet need for a pain relieving, opioid-sparing alternative.



A

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Botanical extract, Chrysanthemum zawadskii var. latilobum (GCWB) studied in 112 w/ mild-mod. knee OA. Randomized, double-blind, placebo-controlled study finds GCQB signif better than placebo in WOMAC total & function scores https://t.co/xyKlrL2CG7

Dr. John Cush @RheumNow( View Tweet )

Jul 19, 2021
Carpal Tunnel Syndrome has an annual incidence of 0.4%. Population based study shows more likely in women, 50-59 years, w/ obesity, gout, rheumatoid arthritis or a prior hx of wrist injury. https://t.co/X7U5yh0R3l

Dr. John Cush @RheumNow( View Tweet )

Jul 19, 2021
ICYMI: News: EULAR Guidelines on Intraarticular Therapy EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. https://t.co/Z6vC0x9zY1 https://t.co/dKpjpo50YT
Dr. John Cush @RheumNow( View Tweet )
Jul 18, 2021
Knee corticosteroids injx within 4 wks of total joint arthroplasty may be assoc w/ a higher risk of postop infection (studies suggest a risk w/in 3 mos of TKA). Greatest risk seen w/in 2 wks of injx (OR 2.89), worse in <65 yrs & w/ comorbidities (RA) https://t.co/nZKTkv7ym5 https://t.co/4W6CNsrqpf
Dr. John Cush @RheumNow( View Tweet )
Jul 16, 2021
Hands-Down Rheumatology - Gout doesnt get to the hands until its done its damage below (MTP, ankle, knee) and usually only in those with severe tophaceous gout Can also present as dactylitis or Carpal tunnel. Women on diuretics w/ CKD can get gout in Nodal OA joints https://t.co/Ri5taWpR0p
Dr. John Cush @RheumNow( View Tweet )
Jul 07, 2021

ICYMI: EULAR Guidelines on Intraarticular Therapy

Jul 07, 2021

EULAR has published evidence-based recommendations on the use of intra-articular therapies (IAT) based on the literature review and recommendations of a multidisciplinary international task force. These IAT recommendations apply to adult patients with peripheral arthropathies.



The

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RheumNow Podcast – As Good As I Ever Was (7.2.2021)

Jul 02, 2021

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

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Health care utilization by knee OA pts varies. In nearly 1 million Knee OA (Medicare), 33% ended up with TKR. TKR/arthroplasty assoc w/ more clinic visits; PT, specialist care & intraarticular Rx assoc. w/ less TKR. TKR range 26% to 42% by region https://t.co/d1EQTTie8X

Dr. John Cush @RheumNow( View Tweet )

Jul 01, 2021
Higher rate of Parkinsonism in Osteoarthritis? Taiwan Health Insurance claims analysis of 33,360 OA pts (age 50-64 yrs) vs age matched non-OA - found incr risk of Parkinsons in OA pts (aHR=1.41), esp in knee or hip OA (aHR 1.55) group. https://t.co/SHudF5NnwH

Dr. John Cush @RheumNow( View Tweet )

Jun 30, 2021
Stroke risk is increased in arthritis (RR 1.36, 95% CI: 1.27–1.46); esp for RA (RR 1.38), AS (RR 1.49), PsA (1.33) & gout (1.40); but NOT osteoarthritis (RR=1.03). Apparently Inflammation drives this risk. https://t.co/Snb6OrtZJH

Dr. John Cush @RheumNow( View Tweet )

Jun 30, 2021

Knee Replacement in Obese OA is Cost Effective

Jun 24, 2021

Debates over ideal candidates for total knee replacement (TKR) in osteoarthritis patients often excludes those who are obese, but a recent article in the Annals of Internal Medicine suggests that TKR is both effective and cost-effective in obese patients (BMI >40 kg/m2)

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Don't Kill the Krill! Dr. Kathryn Dao ( @KDAO2011) reviews abstract POS0276 regarding the efficacy of krill oil in knee OA, presented at the virtual EULAR 2021 meeting. https://t.co/gX2hivyCs2 https://t.co/QaU7A7gM8j
Dr. John Cush @RheumNow( View Tweet )
Jun 21, 2021
Time to go raspberry picking? Rubus idaeus leaf extract 400mg and 200mg after 12 weeks ⬇️ VAS pain in knee OA compared to placebo ⭐️no effect on WOMAC, SF-36, 20m walking Abs#POS0281 #EULAR2021 @RheumNow https://t.co/QAiag2XjRh
Robert B Chao, MD @doctorRBC( View Tweet )
Jun 06, 2021
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