Skip to main content

Cardio/Pulmonary

Microvascular CV Disease with Severe Psoriasis

Sep 26, 2023

While comorbidities, including an increased cardiovascular (CV) risk, are associated with severe psoriasis, less is known about subclinical CV disease and when it occurs in patients with psoriasis. 



Coronary microvascular dysfunction (CMD) has been shown to be predictive of future

Read Article
Large cohort study of hospitalized #AS shows that the leading cause of death in AS were cardiovascular, infectious, respiratory, & traumatic. Mortality risk was signif assoc w/ Elixhauser comorbidity index, CHF, & renal dz. NSAIDs did not increase risk https://t.co/6nlDxvO8pO https://t.co/V3hZq5xQ6Q
Assessing Cardiovascular Risks: The Responsibility of the Rheumatologist In 2016, EULAR posted recommendations for the management of cardiovascular (CV) risks in patients with rheumatoid arthritis (#RA) and other inflammatory joint diseases (IJ D)1. https://t.co/OhE44GkvMB https://t.co/XhoTah7PTp
#RA QD Clinic: Cardiovascular Risk and RA Features Dr. Kathryn Dao (Dallas, TX) A high Risk RA patients - how to manage the cardiovascular risks. https://t.co/jc3fvaP9l3 https://t.co/tYswHxqnNX

TNR: Decisions in Methotrexate

Sep 20, 2023

This Tuesday Night Rheumatology panel discussion on "Methotrexate Decisions" features Drs. Michael Weinblatt, Grace Wright, Richard Conway and Joel Kremer. The​ Panel discussed folate & MTX dosing, side effect management, MTX & lung disease and optimal monitoring, with many audience

Read Article
Hydroxychloroquine Adherence Lowers Cardiovascular Risks A new study shows that adherence to the antimalarial agent significantly lowers future risk of cardiovascular events in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients. https://t.co/XzXcBP7XoO https://t.co/V2EQJ2GlpC

RheumNow Podcast – with Special Guest Dr. Peter Nash (9.15.2023)

Sep 15, 2023

This week, Dr. Jack Cush reviews the news with special guest, Dr. Peter Nash. They discuss COVID Autoantibodies, SpA life expectancy, HCQ, extraarticular RA and our approach to Early RA referrals and pre-clinical RA.

Read Article

RA Extra-articular Manifestations Declining

Sep 12, 2023

A Mayo Clinic population based cohort study shows the extraarticular manifestations of rheumatoid arthritis (ExRA) have declined with time; but the increased mortality risk of RA remains unchanged.



They defined their cohort as adult patients with incident RA (ACR Criteria positive)

Read Article

Hydroxychloroquine Adherence Lowers Cardiovascular Risks

Sep 11, 2023

Daily hydroxychloroquine (HCQ) is better than an apple a day; as a new study shows that adherence to the antimalarial agent significantly lowers future risk of cardiovascular events in rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) patients.

Read Article
New ACR RA-ILD Treatment Guidelines – What Were They Smoking!? #RA @RichardPAConway weighs in. https://t.co/bPB162y6s1 https://t.co/u4B9xN6ISj

RheumNow Podcast – with Special Guest Dr. Janet Pope (9.8.2023)

Sep 08, 2023

This week, Dr. Jack Cush reviews the news with special guest, Dr. Janet Pope. They discuss "Not-non-Inferior", large scale genetic screening, Zoster risk w/ newer lupus drugs, tapering, RA referral problems and the TNR webinar session on "ORAL Surveillance Revisited".

Read Article
Aortic Stenosis Risk in #RA A large cohort study has shown that rheumatoid arthritis (RA) patients are at an increased risk of developing aortic stenosis (AS), undergoing aortic valve intervention, or AS-related death. https://t.co/Az5gf1Ion2 https://t.co/wGdi7ripkt

Oral Surveillance Changes in Advanced Therapy Use in RA

Sep 06, 2023

The safety of tofacitinib and TNF inhibitors was studied in high risk rheumatoid arthritis (RA) patients in the ORAL Surveillance study, which culminated in an FDA warning in January 2021 on the cardiovascular, cancer and VTE risks associated with JAK inhibitor use. These safety concerns and

Read Article

Aortic Stenosis Risk in RA

Sep 05, 2023

A large cohort study has shown that rheumatoid arthritis (RA) patients are at an increased risk of developing aortic stenosis (AS), undergoing aortic valve intervention, or AS-related death.



The risk of incident AS, aortic valve intervention, AS-related death, and risk factors for AS

Read Article

ICYMI: ACR Guidelines for Interstitial Lung Disease in Patients with Rheumatic Conditions

ACR
Sep 04, 2023

The American College of Rheumatology released summaries of two new guidelines for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Disease and for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic

Read Article

SGLT2 Inhibitors as Gout Treatment

MedPage Today
Aug 30, 2023

Patients with gout and type 2 diabetes treated with SGLT2 inhibitors not only had reduced numbers of gout flares, but also lived longer compared with other such patients receiving other medications, researchers said.

Read Article

2023 ACR/EULAR Antiphospholipid Syndrome Classification Criteria

Aug 29, 2023

The American College of Rheumatology (ACR) and EULAR have combined efforts to establish an international multidisciplinary Steering Committee to develop classification criteria for the new antiphospholipid syndrome (APS) to be applied in observational studies and clinical trials.

Read Article
Before COVID, we never worried about the heart from hydroxychloroquine (except very rare cardiomyopathy). This study (Einstein #Lupus cohort) confirms positive benefits with nonsmokers having reduced HFrEF, arrhythmia, and cardiac deaths from 2005-2021; HCQ did NOT increase heart… https://t.co/l1Q2MqDMuX

ACR Guidelines for Interstitial Lung Disease in Patients with Rheumatic Conditions

ACR
Aug 24, 2023

The American College of Rheumatology released summaries of two new guidelines for the Screening and Monitoring of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic Disease and for the Treatment of Interstitial Lung Disease in People with Systemic Autoimmune Rheumatic

Read Article

Cardiovascular Disease Precedes ANCA-associated Vasculitis

Aug 21, 2023

A nested case–control study from the Danish Nationwide Registries finds an increased risk of cardiovascular (CV) disease in the months preceding diagnosis of ANCA-associated vasculitis (AAV).

Read Article

Manifestations of Systemic Sclerosis Sine Scleroderma

Aug 21, 2023

Systemic sclerosis (SSc) sine scleroderma is a unique and rare subset of SSc defined by the absence of skin fibrosis. An analysis of the EUSTAR database suggests systemic disease can be a problem, including interstitial lung disease (>40%) and SSc renal crisis (almost 3%). 

Read Article

Mono- and Oligo- are Different (8.18.2023)

Aug 18, 2023

Dr. Jack Cush reviews the news and journal reports from RheumNow.com this past week.




  1. Glucocorticoid Affects Weight, but not Blood Pressure in RA A pooled analysis of 5 RCTs shows that the effects of 2 years of low-dose glucocorticoid (GC) treatment in RA can significantly

Read Article
Do TNF inhibitors work in cardiac sarcoid (CS)? PET scan study of 31 CS pts Rx w/ infliximab 13, adalimumab 15, adalimumab 3. Mean pred dose dropped 18.6 to 7.7mg, p = 0.018) & PET improved w/ TNFi and only 4 pts had CV hospitalization during F/U https://t.co/WjAiSVXJWI https://t.co/5tDXNa9Usp
A review of Myositis-associated ILD prevalance is 50% (Asia), 23%(N. Amer) & 26% (EU) & is increasing. ILD is more common/severe w PL-7/-PL-12 Abs (vs Jo1). MDA5 Abs higher in Asians (11-60%), assoc w/ rapidly progressive ILD https://t.co/gDg3EHfOPn https://t.co/FWutzVFXGB
Lung is involved in pre-clinical ACPA+ RA! Lung-resident B cells from BAL of 12 untreated at-risk or Dx early RA pts found T cell–driven B cell differentiation resulting in local class switching and somatic hypermutation B cells, esp w/ ACPA+ https://t.co/ZPwRf3ZWAl https://t.co/TDDShB0J5z
×