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Infection

Birthday Gatherings Increase COVID-19 Risk

Jun 24, 2021

How risky are family gatherings, birthday parties and informal social gatherings? A cross-sectional analysis suggests that birthdays may be associated with increased rates of COVID-19 infection within households where there is a high COVID-19 prevalence in the population. 

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Treatment of MIS-C COVID in Kids

Jun 21, 2021

The NEJM has published results of a real-world efficacty trial showing that COVID infected children with the multisystem inflammatory syndrome in children (MIS-C) respond better to initial IVIG plus glucocorticoids (than IVIG alone) which was associated with less subsequent cardiovascular

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Tofacitinib Efficacy in COVID-19 Pneumonia

Jun 21, 2021

NEJM has published the results of an observational trial wherein tofacitinib given to patients hospitalized with Covid-19 pneumonia, was shown to significantly lower risk of death or respiratory failure.



This multicenter trial was conducted in Brazil. A total of 289 hospitalized

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EULAR 2021 – Day 4 Report

Jun 17, 2021

It's been nearly two weeks since EULAR 21 ended. There were several presentations on the last day; notably, the late breaking abstracts and others. Here are a few of my favorites from Day 4, the final day of the meeting.

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RheumNow Podcast - Best of EULAR 2021

Jun 11, 2021

Dr. Jack Cush reviews and highlights his favorite abstracts and presentations from last week's virtual EULAR 2021 meeting.

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#EULAR2021 and EULAR IQ Dr Jack Cush reviews highlight presentations from the first 3 days of EULAR 2021. https://t.co/BkHjhOUqNU https://t.co/4JS1yGiJHg
Dr. John Cush @RheumNow( View Tweet )
Jun 05, 2021
COSMOS study: Guselkumab RCT in PsA pts TNFi-resistants (1 or 2) 44.4% of GUS vs 19.8% of PBO pts achieved ACR20 at w24 (p<0.001) and GUS > PBO for most secondary endpoints. Tolerance: 18% vs. 20% infections/SI. #OP0230 @Rheumnow #EULAR2021 @DrLauraCoates https://t.co/fFle2OR8KM
Aurelie Najm @AurelieRheumo( View Tweet )
Jun 04, 2021
Serious infections and BioDMARDs: what is the confounding factor? BSRBR-RA: 33,916 RA treated w/ BioDMARDs with 62,532 years of follow-up, 2036 SI. HR of SI no longer different among BioDMARDs when adjusted for the line of therapy! #OP0241@Rheumnow #EULAR2021 https://t.co/UG9WrXP7RD
Aurelie Najm @AurelieRheumo( View Tweet )
Jun 04, 2021

RheumNow Podcast - EULAR 2021 & EULAR-IQ (6.4.21)

Jun 04, 2021

Dr Jack Cush reviews highlight presentations from the first 3 days of EULAR 2021.


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Patients with RA > 70yo and risk of severe infection: which therapeutic strategy is the safest? #EULAR2021 @Rheumnow #OP0116

Aurelie Najm @AurelieRheumo( View Tweet )

Jun 03, 2021
➡️5 cases of single-dermatome Herpes Zoster in 4 patients treated w/ UPA 15 mg QD for active AS in SELECT-AXIS 1 ⭐️Do not forgot to vaccinate patients with 1st dose of Shingrix prior to starting a JAK-i. 2nd dose can be given after start of therapy OP0144 #EULAR2021 @RheumNow

Meral K. El Ramahi, MD @MeralElRamahiMD( View Tweet )

Jun 03, 2021
You put a pt on a #Jaki What is most likely infection that will occur? #EULAR2021 @RheumNow @eular_org

Janet Pope @Janetbirdope( View Tweet )

Jun 03, 2021

COLCORONA: Protective Effect of Colchicine in COVID-19

May 31, 2021

Lancet Respiratory Medicine has reported the results of the COLCORONA trial, showing that in patients with PCR-confirmed COVID-19 infection, colchicine led to a significantly lower rate of death or hospital admission from COVID.



Colchicine is an oral anti-inflammatory agent with

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RheumNow Podcast – Heart, Lung & Liver (5.28.2021)

May 27, 2021

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com.

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Methotrexate Impairs COVID Vax Response

MedPage Today
May 27, 2021

One-third of patients with immune-mediated inflammatory diseases being treated with methotrexate showed attenuated responses to the COVID-19 vaccine, researchers reported.



In two independent cohorts, robust antibody responses were observed in 98.1% of healthy controls and in 91.9% of

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Efficacy of 6 Weeks Antibiotics with Prosthetic Joint Infections

May 27, 2021

The NEJM has published the results of a French multicenter study showing that prosthetic joint infections can be successfully managed with 6 weeks of antibiotic therapy; this was noninferior and had better outcomes compared to 12 weeks of antibiotic therapy.



Prosthetic joint

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Tocilizumab Augmented Efficacy in COVID-19 Pneumonia with High CRP

May 25, 2021

JAMA Internal Medicine report an analysis of recent and composite trial data suggesting that tocilizumab (TCZ) therapy in COVID-19–associated pneumonia patients with high CRP levels is likely to be effective.

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Italian study of 1216 rheumatic pts on DMARDs, Biologics underwent HBV testing. They found HBV in 15.7% (chronic infection: 0.4%, resolved infection: 12.6%, anti-HBc positivity alone: 2.6%). HBV reactivation occurred in 6.2%. Only 1 acute hepatitis https://t.co/WofN4rqq6p

Dr. John Cush @RheumNow( View Tweet )

May 24, 2021

Factors Associated with COVID-19 Deaths in Rheumatic Patients

May 24, 2021

Analysis of data from the COVID-19 Global Rheumatology Alliance shows that rheumatic diseases infected with COVID-19 had a greater risk of death with age, comorbidities, high disease activity and few specific therapies.



Rheumatic disease adults with a confirmed or presumptive COVID-19

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RheumNow Podcast – Myth Busters (5.21.2021)

May 21, 2021

Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com




  1. Metanalysis (11 RCTs, 19 registries) of Pulm arterial HTN assoc. w/ CTD (w/ 1,267 & 4,008 CTD-PAH pts), showed Investigational Rxs reduced morbidity/mortality by 36%. CTD-PAH survival

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Lower Rates of Serious Infection with Ustekinumab in Psoriatic Disease

MedPage Today
May 20, 2021

Patients with psoriasis or psoriatic arthritis who were being treated with ustekinumab (Stelara) had lower rates of serious hospitalized infections than patients receiving other biologics or small molecule therapies, a study utilizing data from two commercial claims databases found.

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RheumNow Podcast – BandAids for Rheumatologists (5.14.2021)

May 14, 2021

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com - a website for rheumatologists, by rheumatologists.



We love Rheumatology!




  1. CDC study from 33 sites, 25 states showed vaccine efficacy (against Sx COVID) in HCP was 82% with ONEdose

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RheumNow Live 2021 Now Available for All

May 14, 2021

RheumNow Live (RNL) for 2021 was held March 20 - 21 in Fort Worth, TX, and now all can partake in the meeting - by video, podcast or by signing up for Tuesday Nite Rheumatology (TNR).



RNL has finished its 3rd year as a hybrid meeting, with the live meeting streamed to hundreds at home

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CDC: Fully Vaccinated Can Shed Masks and Resume Travel

May 13, 2021

The U.S. Centers for Disease Control and Prevention (CDC) today updated COVID guidance such that fully vaccinated people do not need to wear masks outdoors, can avoid wearing them indoors in most places, 

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NSAID Safety with COVID-19 Infection

May 12, 2021

NSAIDs do not affect COVID outcomes; here we are nearly 16 months into the pandemic, and this is the common sense conclusion of a recent trial published in Lancet Rheumatology.



Early in the pandemic there was an unfounded directive from the French government suggesting that non-

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