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Myositis

RheumNow Podcast – Sweet Lies or Hard Truths? (2.26.2021)

Feb 26, 2021

Dr. Jack Cush reviews and discusses the news and Journal reports from the past week on RheumNow.com.

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Other than anti-tRNA synthetase Abs, there are several new Abs associated with PM/DM @UTSWNews @UTSWInternalMed https://t.co/EttRB3YYHm
Dr. John Cush @RheumNow( View Tweet )
Feb 25, 2021
Classic path findings in dermatomyositis @UTSWNews @UTSWInternalMed https://t.co/W61OveDSwG
Dr. John Cush @RheumNow( View Tweet )
Feb 25, 2021
An unsual type of adult polymyositis that is not usually steroid responsive - Polymyositis with mitochondrial abnormalities - older patients +COX staining, slow progression. @UTSWNews @UTSWInternalMed https://t.co/2tv1R3e9Qg
Dr. John Cush @RheumNow( View Tweet )
Feb 25, 2021
Rheumatology Grand Rounds with Dr. Dennis Burns - lecturing on neuropathology of inflammatory myositis. Not all Muscle Bxs are positive, estimated sampling error w/ normal findings in 10-15% @UTSWNews @UTSWInternalMed https://t.co/Xm73GuMa3j
Dr. John Cush @RheumNow( View Tweet )
Feb 25, 2021
High Risk Cancer Profiling with Inflammatory Myositis A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs). https://t.co/TjmdGtdDQG https://t.co/tlfVU031fY
Dr. John Cush @RheumNow( View Tweet )
Feb 19, 2021

High Risk Cancer Profiling with Inflammatory Myositis

Feb 18, 2021

A recent metanalysis of studies suggest you may be able to use certain clinical factors to stratify cancer risk in patients with idiopathic inflammatory myopathies (IIMs).

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RheumNow Podcast – Don’t Hold the Benlysta, Take the Vaccine (1.22.2021)

Jan 22, 2021

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com, with more than a dozen items to discuss on this week's podcast.

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Canadian lupus cohort of 560 SLE pts without myositis at baseline. Over time, only 5 pts developed myositis (after mean 8.5 yrs). Incidence = 1.05 per 1000 PYs. Arthritis, Raynauds, -Sm Abs were common, but only non-Whites had increased risk of myositis. https://t.co/fzWhUADjMz

Dr. John Cush @RheumNow( View Tweet )

Jan 21, 2021
44 pts of Inclusion body myositis were randomized to either PBO or sirolimus 2 mg/d. At 12 mos there were no signif differences betw groups for motor strength , but sirolimus had more SAEs (45 vs 27%); yet sirolimus had better HAQ, FVC & 6-min walk times. https://t.co/YhnRTnaGFl

Dr. John Cush @RheumNow( View Tweet )

Jan 18, 2021
ProDERM Study: IVIG in Dermatomyositis--The ProDERM study show that IVIg is safe, effective and superior to placebo in patients with dermatomyositis (DM). https://t.co/HOB8CYn9yc https://t.co/AmT3AQdawa
Dr. John Cush @RheumNow( View Tweet )
Jan 15, 2021

2020 Rheumatology Year in Review

Jan 14, 2021

2020 was historic, memorable and game-changing. Under the cloud of COVID-19, there were many significant and memorable advances and setbacks for the rheumatology world. In our accounting of most read articles for 2020, (not surprisingly) 17/20 were COVID-related. Below, are our top news items

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ProDERM Study: IVIG in Dermatomyositis

Jan 13, 2021

The ProDERM study design and outcomes are previewed in Medicine; and as promised the results were revealed at ACR Convergence in November 2020 showing that IVIg is safe, effective and superior to placebo i(PBO) in patients with dermatomyositis (DM).

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44 patient study of sirolimus vs placebo in patients with inclusion body myositis found no difference in the primary outcome of relative knee extension strength, nor in secondary outcomes. SAE were more common w/ sirolimus 45% vs 27% in PBO https://t.co/YhnRTnaGFl

Dr. John Cush @RheumNow( View Tweet )

Jan 07, 2021
#BestACR20Tweets RT @drdavidliew :The 'triple M' irAEs (myositis/myocarditis/MG): one of the rheumatic irAEs where autoAb are freq pos Nice systematic review: any autoAb+ 61% tested MG+ 59% tested MSA+ in 27% tested (18/67, 11 had myositis alone) https://t.co/aQHapPbjw9
Dr. John Cush @RheumNow( View Tweet )
Dec 07, 2020
IVIg in Dermatomyositis: Dr. Sheila Reyes ( @RHEUMarampa) reviews abstract #0995 presented at #ACR20. https://t.co/PKYATqUh0d

Dr. John Cush @RheumNow( View Tweet )

Dec 02, 2020
Watch our #ACR20 video recap titled "Treatment of Dermatomyositis Studies" with Dr Robert Chao (@doctorRBC). Dr. Chao reviews two important abstracts - #0955 and #0958 - on the treatment of dermatomyositis as presented at the 2020 ACR annual meeting. https://t.co/1hiTZQVjlL https://t.co/CW9OGHTuJg
Dr. John Cush @RheumNow( View Tweet )
Nov 20, 2020
Summary of #ACR20 part C: - A must see talk was the avacopan story - IVIG for myositis does work! More than just anecdotal evidence now - DIET is key to helping improve autoimmune dz! - low dz activity RA pts should taper off of MTX 1st when also on TNFi @jeffsparks @RheumNow

Meral K. El Ramahi, MD @MeralElRamahiMD( View Tweet )

Nov 09, 2020
The 'triple M' irAEs (myositis/myocarditis/MG): one of the rheumatic irAEs where autoAb are freq pos Nice systematic review: any autoAb+ 61% tested MG+ 59% tested MSA+ in 27% tested (18/67, 11 had myositis alone) @NilashaGhosh @lovetolearn27 @got_rheum #ACR20 ABST1574 @RheumNow https://t.co/utSj8yY0fd
David Liew @drdavidliew( View Tweet )
Nov 09, 2020
This cohort study presented by @Dr_Alex_Oldroyd shows that early cancer diagnosis after #myositis onset is associated with significantly improved survival. Cancer screening essential in pts newly diagnosed with IIMs. @RheumNow #ACR20 abs1057 https://t.co/qVsnTcEnWb
Nov 08, 2020
Poll results are in! 75% of those that responded plan to only screen for cardiac manifestations of myositis if a pt develops concerning symptoms. 20% screen for involvement annually w/ a TTE, troponin, BNP, and EKG! @RheumNow #ACR20 https://t.co/crUhFR6Hzf

Meral K. El Ramahi, MD @MeralElRamahiMD( View Tweet )

Nov 08, 2020
Pts are starting to ask me more about turmeric and ginger. Excellent review by Dr. Shah 1⃣Both good anti-inflammatory 2⃣Watch out in pts with bleeding/platelet disorder, menorrhagia, gallstones, PUD 3⃣Supported by trials @RheumNow #ACR20 https://t.co/2U8zDQu64T
Robert B Chao, MD @doctorRBC( View Tweet )
Nov 08, 2020
Dr. Stone Rheum Pearls - B cell therapy treats APS-capillaritis... without effecting aPL titers. #ACR20 @RheumNow https://t.co/5ZJN3xBE57
Eric Dein @ejdein1( View Tweet )
Nov 08, 2020
Great Thieves Market poster by my @jhrheumatology co-fellow Dr. James Son. 27 yo patient with active myositis has this imaging. Check it out for diagnosis! @RheumNow #ACR20 https://t.co/xUT6QkWNAX
Eric Dein @ejdein1( View Tweet )
Nov 08, 2020
Do you obtain baseline and/or serial TTE, EKG, BNP, and TROPONIN* on follow-up visits of your patients with myositis? #ACR20 @RheumNow

Meral K. El Ramahi, MD @MeralElRamahiMD( View Tweet )

Nov 08, 2020
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