Gianfresco et al have published the first peer-reviewed analysis of COVID-19 infected, rheumatic disease patients entered into the Rheumatology Global Alliance registry; showing that a) rheumatic disease patient can be infected with COVID-19, b) that DMARD and biologic use has no apparent effect
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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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This week's Tuesday Nite Rheumatology featured Dr Randy Cron from the University of Alabama - Birmingham as he spoke and took questions on the immunology, immunopathogenesis and treatment of Cytokine Storm Syndrome, especially as they relate to COVID-19 and rheumatic disease patients. The
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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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As data continue to emerge about a multi-system inflammatory disorder in children apparently connected to COVID-19, evidence is growing that this is not your typical Kawasaki disease.
In New York, up to 102 children have reportedly developed this inflammatory syndrome, and three
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Last night's Tuesday Nite Rheumatology featured Dr. Joan Merrill (OMRF). In her lecture, "What does COVID-19 have to do with lupus?", she discusses the pathogenesis of lupus, and specifically thrombotic microangiopathy, complementopathies, catastrophic lupus syndrome and the potential overlap
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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.
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JAMA Internal Medicine has reported that cigarette smoking associated with an increased odds of having antineutrophil cytoplasmic antibody–associated vasculitis (AAV) (especially MPO positive AAV) and is thereby a modifiable risk factor for AAV.
In a case-control study, 473 AAV
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Pediatricians are asking the question - could this be a rare manifestation of COVID-19 in children?
There are now 3 case reports in the U.S of children infected with the coronavirus who have developed what looks like Kawasaki's diseaes. Simimar reports have been seen in the UK, Italy
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Dr Jack Cush reviews the news, journal reports, twitter feed and COVID developments from the past week on RheumNow.com
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The Journal of Rheumatology reports a retrospective, single center, analysis of 17 rheumatoid vasculitis patients who responded well to intravenous rituximab (RTX) therapy.
They identified 17 patients treated with RTX for systemic rheumatoid vasculitis from 2000 to 2017. At RV
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Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com
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Risks of infection were strikingly high among patients with antineutrophil cytoplasmic antibody-associated (ANCA) vasculitis, which may relate to both the disease and its treatment, Scottish researchers found.
Compared with matched controls from the general population, the risk of
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The Journal of Rheumatology reports the findings of a Swedish population-based cohort study of biopsy-proven giant cell arteritis (GCA) patients showing that the overall risk for cancer was not increased; yet there appears to be an increased risk for leukemia and a decreased risk for breast
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Rheumatology reports on a study of patients with granulomatosis with polyangiitis (GPA) showing worse outcomes and higher costs when hospitalized with GPA.
GPA patients were identified from the Nationwide Inpatient Sample (NIS) and were compared to those without GPA with regard to
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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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NICE has commissioned an update to the 2010 British Society for Rheumatology guideline for the management of giant cell arteritis, and proposed a total of 19 recommendations for the diagnosis and treatment of GCA.
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The PEXIVAS study showed that plasma exchange did not reduce the incidence of death or ESKD in patients with severe ANCA–associated vasculitis.
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A controlled clinical trial has shown that giving the IL-6 receptor antibody, tocilizumab (TCZ), to patients with Takayasu arteritis (TAK) results in clinical efficacy and has a steroid sparing efffect.
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Dr. Jack Cush reviews the journal reports and news from RheumNow.com.
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The French Vasculitis Study Group has published that patients with systemic necrotizing vasculitis do not have an increased risk of malignancy; in fact they have a risk that is similar to the general population.
Previous reports have suggested either no risk or a declining risk in the
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IgG4-related disease (IgG4-RD) is a relatively new disorder since 2003, and may present as a diagnostic challenge as it can cause fibroinflammatory pathology in nearly any organ.
A EULAR workgroup set out to develop and validate an international set of classification criteria for IgG4-
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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.
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Flares of vasculitis can still be a problem after hepatitis C-related cryoglobulinemic vasculitis patients are cured of their hepatitis C by direct-acting antivirals, as demonstrated by data from four registries presented at ACR 2019 in Atlanta, Georgia.
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Annals of Internal Medicine reports that age-adjusted mortality rates for antineutrophil cytoplasmic autoantibody–associated vasculitides (AAV) have improved over time - with a decline of nearly 2 percent per year in the United States from 1999 to 2017. Nevertheless, long-term outcomes continue
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