RT @ericdeinmd: Tomorrow at 3 pm at #ACR22! Join my session on Difficult to treat RA - How do define it? - What are the

Article Rheumatoid Arthritis

Difficult to Treat Rheumatoid Arthritis

Jack Cush, MD Jan 29, 2026

Dr. Cush addresses the management of difficult-to-treat rheumatoid arthritis (D2TRA).

Article Rheumatoid Arthritis

“ABCDE” Approach to Difficult-to-Treat Rheumatoid Arthritis

Jack Cush, MD Sep 2, 2026

The proposed approach to difficult-to-treat rheumatoid arthritis is based on the EULAR definition (having failed 2 or more b/tsDMARDs). The authors provide guidance in the form of an easy acronym, A B C D E, which covers both diagnostic and therapeutic considerations.