Articles By Jack Cush, MD
Dietary Intake Triggers Inflammation
IL-1β, along with pancreatic insulin, helps regulate blood sugar levels, as well as chronic inflammation.
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Patient and Provider Education Fails to Improve Osteoarthritis Outcomes
A randomized trial of 537 knee osteoarthritis (OA) patients in the Duke Healthcare system has shown that patient- and provider interventions were no better than the usual standard of care.
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Rituximab Effects on ANCA, IgG and Infectious Risk in ANCA-Associated Vasculitis
Rituximab has significantly changed the management of patiehts with ANCA-associated vasculitis (AAV). Yet the longitudinal assessment of such patients needs to be guideded by clinical and laboratory parameters.
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The RheumNow Week in Review – 13 January 2017
Dr. Jack Cush reviews highlights from this past week on RheumNow.com:
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Psoriatic Arthritis Patients have More Heart Disease
A study of 90 consecutive male (50.3±11.1 years) with psoriatic arthritis (PsA) were were compared to 240 age matched controls without known cardiovascular (CV) diseases who underwent angiography for chest pain and/or multiple CV risk factors.
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Statins Don't Increase Risk of Colchicine Myopathy
Neuromyopathy is a rare side effect of chronic colchicine use. Statins are more commonly implicated as a cause of drug-induced myopathy. Given the frequent occurrence of the metabolic syndrome, simultaneous use of both colchicine and statins is common.
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TREG Innovators Win the Crafoord Prize
The 2017 Crafoord Prize from the Royal Swedish Academy of Sciences has been awarded to a Japanese scientists and two American scientists for their discovery and research on T regulatory cells (TRegs).
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Multiple Comorbidity Risks with Giant Cell Arteritis
Elderly patients treated with high doses of corticosteroids are bound to have multiple medical problems. But this was only recently quantified by researchers analyzing a a population-based cohort of biopsy-proven giant cell arteritis (GCA) patients in Southern Sweden.
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The IL-6 Wars
In the years to come, the availability of numerous new IL-6 inhibitors it will either complicate treatment decisions, alter existing treatment paradigms, or result in an all-out war against TNF inhibitor dominance. Data, differences and time will tell.
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Less Education Yields Higher Cardiovascular Risk
Similar to the findings in rheumatoid arthritis, lower levels of education can have predictable negative consequences. And the reasons for more heart attacks with lower educational levels is not entirely clear.
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