Articles By Jack Cush, MD
Psoriatic Arthritis Has a New FDA Approved DMARD - Apremilast
In March 2014 the FDA approved apremilast (Otezla) for use in psoriatic arthritis based on three large"Palace" trials involving 1493 psoriatic arthritis patients. This ACR Hotline reviews the drugs use, efficacy, and toxicity.
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Hemophagocytic Syndrome in Adults
Hemophagocytic lymphohistiocytosis(HLH) is a rare complication of many disorders. In children, systemic JIA is by far the most common cause of HLH.
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Celebrex Goes Generic
The generic drug manufactuer Actavis joins Teva and Mylan with their lauch of celecoxib (Celebrex)in 50 mg, 100 mg, 200 mg and 400 mg capsules. In 2013 celecoxib was the 21st leading prescribed drug in the U.S. with $2.4 billion in sales as of mid 2014.
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Night-time Gout Onset is Not Related to Alcohol or Purine Intake
Gout's often told tale of a nocturnal rapid onset and dramatic pain provoked by a bed sheet, is studied in detail by Choi and the Boston online gout study. This report shows that more than half the attacks occur late night and are unrelated to alcohol or purine intake.
Read ArticleWait a minute: how much to develop a new drug?
Older estimates suggested it would cost $1 billion to develop a new drug. ThisNY Times article discusses newer estimates claiming it cost 2.6 billion to bring a new drug to market.
Read ArticleNobel Prize goes for $4.8 million at auction
Dr James Watson, of Watson and Crick double-stranded DNA fame, has offered up his Nobel prize for auction, with the intention of donating the proceeds to medical institutions which he says has nurtured him, and scores of others, during his career.
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