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Articles By Jack Cush, MD

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ARIAA Trial: Abatacept Delays the Onset of RA

The ARIAA trial tested the utility of IV abatacept in individuals ACPA+ arthralgia patients with subclinical inflammation and showed abatacept to decrease MRI inflammation, clinical symptoms, and risk of future rheumatoid arthritis (RA) development.

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Cochrane Review: How Good is Ultrasound Diagnosing GCA?

Is temporal artery ultrasound equivalent or superior to the reference standard of temporal artery biopsy when diagnosing giant cell arteritis (GCA)?

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Curbside Consults (2.16.2024)

Dr. Jack Cush answers audience clinical case questions sent by email or "ask Cush anything". Cases and questions from:

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APIPPRA Trial: Abatacept in at-risk rheumatoid arthritis patients

Abatacept has been studied in seropositive clinically suspect arthralgia patients (at risk for rheumatoid arthritis) and shows the potential to delay or prevent the disease. 

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Oral IL-23 Inhibitor Effective in Psoriasis

The NEJM has published the results of the FRONTIER 1 trial demonstrating the efficacy of JNJ-77242113, an oral interleukin-23 (IL-23) receptor antagonist peptide, in patients with psoriasis (PSO). 

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VITAL Info on Autoimmune Disease (2.9.2024)

Dr. Jack Cush reviews the journal reports from the past week on RheumNow.com. Highlights are summarized by three songs: "Stairway to Heaven", "You're No Good", and "How Long (has this been going on)".

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Poly-Refractory Rheumatoid Arthritis

Refractory of difficult to treat (D2T-RA) rheumatoid arthritis (RA) comprises a minority of patients that can be categorized by clinical and imaging parameters to formulate a better therapeutic approach. 

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Inflammatory Arthritis in Systemic Sclerosis is Problematic

Inflammatory arthritis (IA) is a common manifestation in systemic sclerosis (SSc), affecting nearly one-third of patients.

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VITAL Study - Autoimmune Prevention Requires Continued Supplements

In the 2 years that followed the termination of the VITAL study, the preventative effect of vitamin D on incident autoimmune disease disappeared with supplement discontinuation; but n-3 fatty acid treated individuals had a sustained benefit in reducing the risk of autoimmune disease.

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Determinants of Gout Flares

Approximately 12 million US adults in the US have gout. Two recent literature reports highlight contributors to gout flares.

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