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A Dentist’s Three Tips to Stay on Muscarinic Agonists in Sjögren Disease
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Jiha Lee, MD

Nov 04, 2026

Resolution of dryness remains a key unmet need for patients with Sjögren disease (SjD), as highlighted by the Sjögren SIG session “How to treat SjD” on the final day of APLAR 2026. A rheumatology talk in the session noted that recent phase III trials of ianalumab, dazodalibep and telitacicept improved ESSDAI scores, with only some evidence of benefit for dryness itself. Symptomatic care therefore still carries the load. Masafumi Moriyama, DDS, PhD, offered practical insight from the oral health side.
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Autologous HCT in Severe Systemic Sclerosis

Jack Cush, MD Nov 04, 2026

An international study reports 60% progression-free survival at 10 years after autologous bone marrow transplantation, adding important evidence on sustained positive clinical outcomes and long-term safety in patients treated for early severe systemic sclerosis.

APLAR 2026: The Rheumatologist and AI https://t.co/g81loiW0pI https://t.co/udiw3eoNJr

APLAR 2026: The Rheumatologist and AI | RheumNow

FDA Approves Tildrakizumab for Psoriatic Arthritis Sun Pharmaceuticals announced Friday that the FDA has approved its IL-23 inhibitor, tildrakizumab (Ilumya) for use in patients with active psoriatic arthritis. https://t.co/9vJoJ35iso https://t.co/4ePITTmPl8

FDA Approves Tildrakizumab for Psoriatic Arthritis | RheumNow

Intra-Articular Injections for Knee OA: Options, Evidence, and no Clear Winner At APLAR 2026 in Seoul, the OA special interest group offered a whirlwind overview of IA injectables from Dr. Gun-il Im. The products fall into three tiers: symptom-modifying, biologic/regenerative https://t.co/jWuinfM2W6

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The Concern about Seronegative RA

Jack Cush, MD Nov 03, 2026

A current review of seronegative RA (SNRA) by D’Onofrio, et al in npj Autoimmunity shows the diverse fate of seronegative RA - which can resolve, persist or become refractory. Clearly dedicated trials of SNRA are needed to better predict.

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Pregnancy in Lupus Nephritis and RA: Managing risks and treating to target

Sheila Reyes, MD Nov 03, 2026

A significant proportion of patients with rheumatologic disease are of reproductive age, therefore, navigating reproductive health is now widely recognized as a fundamental component of modern rheumatology care.

DERM on RheumNow (October 2026) The Derm on RheumNow podcast is a review of recent citations and content curated for dermatologists – Features Dr. Jack Cush, Editor at RheumNow. https://t.co/AfVKHsj47T https://t.co/LlWIKdyFJ1

DERM on RheumNow (October 2026) | RheumNow

Exagen studies 192 established RA pts (383 controls) for Abs: CCP2, RF IgA, RF IgM, PAD4 (IgA, IgG). RA signif assoc w/ CCP2+ (OR 110), RF (>7), PAD4 (3.5-5.9). In CCP neg - only PAD4 IgG (2.87) & RF (2.2) assoc w/ RA, w/ only small Dx gain (ΔAUC 0.02–0.04). https://t.co/isf7aMf24O

Spanish Nationwide registry study of 5120 hospitalised #GCA pts (2016-2024) found that 54 (1.1%) Dx / aortic aneurysm (AA) & 41 (0.8%) developed AA on F/U (AAf group). Median time to AA Dx 2.7 yrs. AA Risk was higher in males (RRR 2.42) & smoking w/ GCA (RRR 3.23) https://t.co/eZVGKbOfQt

THe the International Federation of Psoriasis Associations has announced that the 8th World Psoriasis & Psoriatic Arthritis Conference will be taking place in Stockholm on 20–22 May 2027. Registration is open. https://t.co/lq5XdcZlki https://t.co/AYGCnwzeue https://t.co/fy6UUCbcxf

AxSpA SIG Baraliakos - CD74 abs in SpA - what other abs need exploration? @RheumNow #APLAR2026 https://t.co/rftgYQH4mX

Key messages from Dr. Vaidya’s talk: - Assocn’s of hyperuricemia or gout with MetS shows a bidirectional trend - Causality: MetS as an upstream driver for gout devt Going beyond jt dse & ULT. What addt’l assessments do you do for your gout pts? @RheumNow #APLAR2026 https://t.co/M6XVoRQ5rz

Perspective from dentists on SjD dry mouth: muscarinic agonists (pilocarpine, cevimeline) help, but side effects limit use. Two ways to improve it: split pilocarpine dosing (2.5 mg four times daily) and a cevimeline mouth rinse in 6 or more divided doses. #APLAR26 @RheumNow https://t.co/phiLD0qaoR

@RheumNow Do the two fixes work? Split pilocarpine (n=20 SjD, 4 weeks): sweating severity 3.7 to 1.7 (p<0.001), oral dryness VAS 61.0 to 43.6 (p=0.011). Cevimeline rinse (n=12 SjD): unstimulated salivary flow higher than juice control at 1 and 2 h. Small studies. #APLAR26 @RheumNow https://t.co/LEDHFGwh8Q

Lupus/LN should not be a sole indication for a C-section C-section should be reserved for obstetric indications. Adapt a multidisciplinary approach. @RheumNow #APLAR2026 https://t.co/vrXeNP9xLI

https://x.com/RHEUMarampa/status/2116726182029009040/photo/1

There is physiologic proteinuria in pregnancy so be careful before attributing a rise of levels to active LN LN flare vs. pre-eclampsia: both can present w/ HTN, edema, low plts and inc crea. > monitor C3 changes during each trimester of pregnancy @RheumNow #APLAR2026 https://t.co/Pp6GGeLPC6

Monitoring ILD in SjD: reassess risk at every visit. High risk with disease duration under 1 year: PFTs every 3-6 months, HRCT at 1 year. Lung biopsy has no role in diagnosis, except for atypical HRCT features or to exclude malignancy. #APLAR26 @RheumNow https://t.co/tFPNi0S8y8

The growing unmet needs of repro health in the @APLAR_org region lead to dev’t of new consensus statements Provides a practical guide for rheums focusing on key areas like preconception, meds safety in pregnancy & men w/AIRDs planning to become fathers etc @RheumNow #APLAR2026 https://t.co/xCKmpcD4ma

Same molecule, different route, different persistence: golimumab IV persisted 4.44 yrs vs 2.07 for SC in biologic-naive RA (n=9,464, Korean claims). Is it the route, or differenntial out of pocket cost, or supervised dosing and better adherence? P#240 #APLAR26 @RheumNow

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Podcasts

Individualized PsA Treatment With an IL-23i or a JAKi
Nov 02, 2026
DERM on RheumNow PODCAST (October 2026)
Oct 31, 2026
Mixed Drinks, Mixed Results (10.30.2026)
Oct 30, 2026
Advances and Challenges in Lupus Care: Insights from RheumNow Survey Findings
Oct 28, 2026

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Therapeutic Updates

Individualized PsA Treatment With an IL-23i or a JAKi

Sponsored by AbbVie Medical Affairs + Health Impact

Nov 01, 2026

In Part 2 of our PsA management series, Saakshi Khattri, MD, and Lindsay Tom, PA-C, discuss tailoring treatment for patients with multidomain PsA and how IL-23i and JAKi data guide their decisions

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