Recent News
The NEJM has published a report from van Vollenhoven et al showing a new dual B cell inhibitor, telitacicept, to be effective when given to active systemic lupus erythematosus (SLE) patients; but this comes with a few safety concerns.Read Article
SAIL-RA: Finding ILD in Early RA
Cohort study of early rheumatoid arthritis (RA) patients finds that interstitial lung disease (ILD) begins early in the course of RA, with certain factors enhancing this risk.
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Muscle mass & JAKi? 15 active RA pts (+ sarcopenia risk) Rx w/ tofacitinib - signif. improved @1 mo. @6 mos muscle mass signif improved (+242 cm3, +4%, p=0·017) {less w/ NSAIDs); w/ signif creatinine incr (0.06 mg/dl) & decr in serum IL-6, IL-1 & TNF. No change in CK, myoglobin, https://t.co/taY7DisMOS
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Why Brittle Bones Aren't Just a Woman's Problem
Osteoporosis is more common in women, prompting routine screenings for them at age 65. As a result, men might overlook getting a scan, which may not be suggested by an orthopedic specialist. However, about 20% of men over 50 will https://t.co/ggyse5ZDPV
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Pregnancy Management in Inflammatory Bowel Disease: A Global Consensus
Consensus guidance on the management of pregnancy in patients with inflammatory bowel disease (IBD) was simultaneously published in six international journals, including The American Journal of https://t.co/F6er2mpUoV
Dr. John Cush @RheumNow ( View Tweet)
BMJ Systematic review of 217 RCTs w/ 15 684 pts shows most beneficial exercises for Knee Osteoarthritis are aerobic activities such as walking, cycling, or swimming significantly mitigated pain during both short and mid-term follow-up periods https://t.co/WmQBFNis6t https://t.co/KXv2mogvZx
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Osteonecrosis: suspect with trauma, high-dose steroids, alcoholism, renal failure, transplantation, SLE, thrombotic states (e.g., sickle cell anemia, hemoglobinopathies), radiation injury, pancreatitis, gout, pregnancy, hyperlipidemia, & caisson disease (decompression sickness) https://t.co/y6iYd5fWZ2
Dr. John Cush @RheumNow ( View Tweet)
Skin Biopsies to Predict Scleroderma Outcomes?
Researchers from the Hospital for Special Surgery and Weill Cornell Medicine have shown that skin biopsies in patients with systemic sclerosis (SSc) can define a fibroblast immunophenotype that may have prognostic and early treatment decision impact.
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Arthritis Pain and Education Gaps Linked
EurekAlert!
New research from The University of Texas at Arlington shows that differences in state welfare policies are linked to rising arthritis-related joint pain across much of the U.S.
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Review of IL-1 family cytokines in inflammation and immunity - including, IL-1, IL-18, IL-33, IL-36, IL-37, IL-38, IL-1Ra, etc. Full read -- Good Reference!! https://t.co/01o05qYPjU https://t.co/HLcfPM2cPw
Dr. John Cush @RheumNow ( View Tweet)
Scientific American takes a look at the beneficial effects of:
Omega-3 Fatty Acids
Vitamin D
Curcumin
(basic overview for all) https://t.co/jv5FrGQQLJ https://t.co/vP26OPaTiS
Dr. John Cush @RheumNow ( View Tweet)
A cohort study of 1 548 538 mother-child pairs with antenatal exposure to steroids (ACS) found a significantly increased risk of res v nonrespiratory infections in preterm & full-term children up to 21 years. (incidence rate, 65 vs 40 & 30 vs 18 per 1000 person-Yrs, https://t.co/Vh4TNYMXgo
Dr. John Cush @RheumNow ( View Tweet)
MSK Manifestations in Pediatric IBD
Arthritis and musculoskeletal (MSK) symptoms may accompany pediatric-onset inflammatory bowel diseases (pIBD) as an extra-articular intestinal manifestation, but may vary in presentation and clinical course.
https://t.co/VoU3itr0EM https://t.co/ar19JdrsHH
Dr. John Cush @RheumNow ( View Tweet)
Mediterranean Diet Efficacy in Psoriasis
A small clinical trial found that a 16-week Mediterranean diet reduced psoriasis severity, presumably due to anti-inflammatory benefits of extra virgin olive oil, plant-based foods, and moderate meat consumption, according to a study https://t.co/nAVgtOq26l
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Why Brittle Bones Aren't Just a Woman's Problem
MedPage Today
Ronald Klein was biking around his neighborhood in North Wales, Pennsylvania, in 2006 and tried to jump a curb. "But I was going too slow -- I didn't have enough momentum," he recalled. As the bike toppled, he thrust out his left arm to break the fall. It didn't seem like a serious accident, yet "I couldn't get up," he said.
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Pregnancy Management in Inflammatory Bowel Disease: A Global Consensus
Consensus guidance on the management of pregnancy in patients with inflammatory bowel disease (IBD) was simultaneously published in six international journals, including The American Journal of Gastroenterology.
Read Article
~1/3 non-IPF ILD progresses over time. KL-6, a new biomarker, retro study of 10 European centers, 303 pts - 37% progressed (⩾10% FVC decline) after 1yr. 5 predictors of progression: age, gender, BMI, FVC, KL-6. (superior to KL-6 alone) w/ 55% sensitivity, 73% specificity 67% https://t.co/i0Uc8DPHaM
Dr. John Cush @RheumNow ( View Tweet)
Tertiary center study of 147 GPA pts (age ~45, 18 mos F/U) - total of 55 deaths& 179 relapses (in 117 pts;1.53/pt). Predictors of relapse (~2 fold incr) = Age > 55, male, ^^creatinine & CNS dz. Mortality assoc w/ ≥ 55 yrs, male, creatinine >1.3, CNS @baseline https://t.co/GzScokrN7G
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🎓 Learning just got smarter.
Every week, RheumIQ challenges you with a quick quiz on current rheumatology updates.
💡 Educational
🎯 Evidence-based
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Try it now and level up your clinical knowledge:
https://t.co/JWTPUViFkI https://t.co/Iihm22wWz6
Dr. John Cush @RheumNow ( View Tweet)
Eating Crow (10.10.2025)
Dr. Jack Cush reviews the news, FDA approvals, and journal articles. In this episode: HMGCR Abs, FDA approvals and Cush eats crow.
https://t.co/n5W8c7OeKS https://t.co/LXAxrE37WS
Dr. John Cush @RheumNow ( View Tweet)
From the blog
Podcasts
Eating Crow (10.10.2025)-
Associations in Rheumatology (10.3.2025)
ILD Diagnosis, Screening and Monitoring
A JAKi CHAT: Shared Decision-Making in RA Sponsored by AbbVie Medical Affairs + Health Impact
Therapeutic Updates
A JAKi CHAT: Shared Decision-Making in RA
Sponsored by AbbVie Medical Affairs + Health Impact
Experts Dr. Jeffrey Curtis and Dr. Kevin Winthrop discuss best practices for shared decision-making, how to talk with patients about the risks of poorly controlled RA, and ways to use a new tool for visualizing the long-term safety of a JAKi.
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Watch our 11-video series on ILD Treatment and Guidelines including videos on assessing ILD, guidelines caveats and concerns, and more.
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Poster Hall
Sponsored by AbbVie Medical Affairs + Health Impact
