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Scary IPAF

Daric A. Mueller, PA-C

Interstitial pneumonia with autoimmune features (IPAF) describes patients who have interstitial lung disease (ILD) plus clinical, serologic, or morphologic features of autoimmunity but who do not meet criteria for a defined connective tissue disease.

Dr. John Cush
@RheumNow
EGPA Treatment: A new Era with the E-MERGE trial? EGPA is the rarest of the ANCA-associated vasculitides. Compared with GPA and MPA, EGPA has a mechanistically distinct pathophysiology involving eosinophil-mediated inflammation. This distinct mechanism has driven the https://t.co/gP5y6rCUJH
Dr. John Cush
@RheumNow
The shifting sands of glucocorticoid use in SLE Despite the rapid development of emerging therapies for SLE, glucocorticoids remain an important component of disease management. "How well do our current corticosteroid prescribing habits align with current treatment guidelines?" https://t.co/kyZWVERLMP
Dr. John Cush
@RheumNow
RheumNow’s expanded coverage of #ACR26 annual meeting is sponsored by UCB. All coverage content is independently selected by RheumNow and its faculty.
Dr. John Cush
@RheumNow
RheumNow’s expanded coverage of #ACR26 annual meeting is sponsored by Eli Lilly and Company. All coverage content is independently selected by RheumNow and its faculty.
Dr. John Cush
@RheumNow
RheumNow’s expanded coverage of the #ACR26 annual meeting is sponsored by UCB. All content is independently selected by RheumNow and its faculty.
Dr. John Cush
@RheumNow
RheumNow’s expanded coverage of the #ACR26 Annual Meeting is sponsored by Beeline Medicines, Boehringer Ingelheim, Bristol Myers Squibb, and Tonix. All coverage content is independently selected by RheumNow and its faculty.
Antoni Chan MD (Prof)
@synovialjoints
SPACE, 67 axSpA patients over about 2 years: low dose CT was 2.3 to 2.7 times more responsive to spinal change than mSASSS, followed by MRI bone spurs (2.1). Key finding: low dose CT was the most responsive modality, and absolute progression was low with all methods. @rheumnow
Antoni Chan MD (Prof)
@synovialjoints
LLM extraction from 488 PsA records (Columbia): 42.6% met full CASPAR criteria and 43.2% had inflammatory features without full CASPAR. Key finding: CASPAR features were extracted at scale, while cDAPSA was documented in 4.9% of records. @rheumnow #ACR26 Abstract#1348
Antoni Chan MD (Prof)
@synovialjoints
Fibromyalgia was present in 9.3% of 151 SpA patients, with ASDAS CRP 3.7 vs 2.2 without it. Key finding: fibromyalgia was associated with higher disease activity and poorer function, and the six item FiRST had a negative predictive value of 98.4%. @rheumnow #ACR26 Abstract#1354
Antoni Chan MD (Prof)
@synovialjoints
Nociplastic pain in axSpA (OHSU): 32.5% of 83 patients had FSQ of 13 or more. FSQ correlated with ASDAS CRP (r 0.53) and lower pressure pain thresholds. Key finding: nociplastic features were common and associated with higher disease activity scores and female sex. Watch my video
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