Recent News
Read ArticleDr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Location matters; Geo-rheumatology?
Digital Self Screening for Arthritis Diagnosis
A new study evaluates patient use of a mobile AI–based symptom checker for diagnoses, but demonstrated only modest accuracy when applied to a cohort of patients with joint symptoms.
https://t.co/YLkheDOrdI https://t.co/MFMEYifP3W
Dr. John Cush @RheumNow ( View Tweet)
RA & OA: Nearly 40% have Anxiety, Depression or Fibromyalgia
Researchers at Rush University analyzed clinic MDHAQ data and found between 36-40% of OA and RA patients screen positive comorbid anxiety (ANX), depression (DEP), or fibromyalgia (FM).
https://t.co/ZElo9iPfA6 https://t.co/dcE0fAsp2N
Dr. John Cush @RheumNow ( View Tweet)
DBRPCT of Krill oil (4 g/d;KOC) vs PBO in 78 #SLE pts for 24 wks. KOC Rx pts had signif increase in Omega-3 Index 4.3% to 7.17% (4wks) to 8.05% (24wks) w/ no change SLEDAI-2K. But 9pts w/ hi activity (SLEDAI≥9) showed signif Dz activity improvements https://t.co/ODLqqZzGQx https://t.co/tehHk4MhbZ
Dr. John Cush @RheumNow ( View Tweet)
NEJM Case: A 29-year-old woman with SLE presented to the dermatology clinic with 2-weeks of itchy, painful rash on her nose and hands that came on with cold weather. What do you think? https://t.co/NvaM4mVJWd https://t.co/QFtC47ZOv9
Dr. John Cush @RheumNow ( View Tweet)
Metformin Protects? TrinetX retrospective propensity matching study compared SLE pts on metformin (n 9,178) vs NOT (78,983). SLE NOT on metformin had signif higher risk of lupus nephritis (RR 1.70), CKD (1.27), & MACEs (1.21) & persited for 5yrs https://t.co/78VjEHs8dJ https://t.co/A6lz32fp0T
Dr. John Cush @RheumNow ( View Tweet)
PEXIVAS: Diffuse Alveolar Hemorrhage in ANCA-Associated Vasculitis Patients
A secondary analysis of the PEXIVAS study showed antineutrophil cytoplasmic antibody–associated vasculitis (AAV) patients complicated by diffuse alveolar hemorrhage (DAH) may have improved with plasma exchange and glucocorticoids, the results did not achieve significance.
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Biologics Prevent AA amyloidosis progression to ESRD
The study suggests that biologic drugs can prevent serious complications of rheumatologic and autoimmune diseases, with some products showing greater effectiveness than others.
https://t.co/f04Jrzy9ae https://t.co/O6dgD5RvxZ
Dr. John Cush @RheumNow ( View Tweet)
Patients with Financial Limits Struggle with Medication Adherence
The National Health Interview Survey reveals that nearly 1 in 5 patients with rheumatologic disease in the U.S. face economic challenges, including food insecurity and CRM nonadherence.
https://t.co/DhiLDq3fjZ https://t.co/zqQRAJDrzc
Dr. John Cush @RheumNow ( View Tweet)
Bad News Coronary Artery Calcium in Rheumatic Patients
In the 2024 SCCT meeting, Dr. Brittany Weber presented findings showing that incidentally discovered CAC in patients with IMID can lead to worse outcomes, even without prior ASCVD.
https://t.co/aJhf0IL1WW https://t.co/uMl89rXjBK
Dr. John Cush @RheumNow ( View Tweet)
Earlier RA Diagnosis Leads to Lower Costs of Care
A study from the Leiden Early Arthritis Clinic shows that is RA is diagnosed within 12 weeks after symptom onset, treatment costs were lower in both autoantibody-negative and autoantibody-positive RA.
https://t.co/TnrpZGZ4fX https://t.co/elNQ3Pde2a
Dr. John Cush @RheumNow ( View Tweet)
CDC warns of Listeria outbreak assoc w/ deli meats - in 12 US states (lead by NY, and MN, MO, IL, WI, PA, VA, GA, NJ, DE, MD, MA, NC), 28 cases, 28 hospitalized, 2 deaths. @risk are the pregnant, elderly, immunosuppressed. Cook deli meats >165F https://t.co/SWKMhIBQEi https://t.co/snLjBKn1UJ
Dr. John Cush @RheumNow ( View Tweet)
Digital Self Screening for Arthritis Diagnosis
There are numerous impediments to diagnosis or referral; and a new study evaluates patient use of a mobile artificial intelligence (AI)–based symptom checker for diagnoses, but demonstrated only modest accuracy when applied to a cohort of patients with joint symptoms.
Read Article
RA & OA: Nearly 40% have Anxiety, Depression or Fibromyalgia
Researchers at Rush University analyzed clinic MDHAQ data and found between 36-40% of osteoarthritis and rheumatoid arthritis patients screen positive comorbid anxiety, depression, or fibromyalgia.
Read Article
Cross-sectional study of 154 adult DLE pts in the Philadelphia area assessed DLE Dz severity (by CLASI) & geoghraphic distribution to ID area deprivation (ADI). ADI > 5 (geospatial disadvantaged) was assoc w/ signif (4X) higher risk of mod-Severe Damage https://t.co/dgeGwzNTKm https://t.co/B3hmUE1G9U
Dr. John Cush @RheumNow ( View Tweet)
2001-2004 NHANES population study shows 28% report hx of erectile dysfunction (ED) & 19% w/ arthritis. Having arthritis was assoc w/ 4 fold higher ED risk; mostly in #OA (OR=1.11), RA (OR=1.03). https://t.co/L2LhEPH9DY https://t.co/yLhVmLw7nt
Dr. John Cush @RheumNow ( View Tweet)
Drug Safety Update, from UK MHRA, shows impt interaction between tramadol and warfarin. Tramadol may increase the INR with risk of major bruising and bleeding when warfarin and tramadol are taken concomitantly. https://t.co/mgmeMJzdLa
Dr. John Cush @RheumNow ( View Tweet)
Inpatient study 5495 Adult Stills Dz (AOSD) hospitalizations (2016–2019). Pts w/ HLH (6.2%) had higher mortality (9% vs 1.5%). Deatjs Independent predictors: DIC (OR 6.1), liver failure (7.2), Infx (3.7), resp failure (6.9),thrombotic microangiopathy (14) https://t.co/BQsbVnw2Ir https://t.co/mbn9JuN7ow
Dr. John Cush @RheumNow ( View Tweet)
UK Natl Early Inflammatory Arthritis Audit (5/18-10/22) compared 682 persistently active vs 1026 low activity RA pts. pactiveRA were younger, more women. pactiveRA assoc. w/ Age, gender, smoking, depression, lung dz, gastric ulcers, baseline steroids https://t.co/QGuUZmSBHD https://t.co/TDlPFmTQEn
Dr. John Cush @RheumNow ( View Tweet)
Whats it like to be a Rheum? AMA shadows 11 yr rheumatologist Dr. Amish Dave - typical day, challenging aspects, burnout, lifestyle, skills, insights and med student advice - Thanks Dr. Dave!! https://t.co/NY44hhjTYA https://t.co/809RBgSokM
Dr. John Cush @RheumNow ( View Tweet)
Potential of Radiomics to Predict TNF Therapy Outcomes in axSpA
Dr. Bella Mehta interviews Dr. Vincenzo Venerito about abstract POS0236 at Eular 2024 in Vienna, Austria.
https://t.co/ZR5pFINagR https://t.co/bEWjSXWlB0
Dr. John Cush @RheumNow ( View Tweet)
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