Knee Replacement in Obese OA is Cost Effective
Jun 24, 2021
Recent News
Read ArticleDebates over ideal candidates for total knee replacement (TKR) in osteoarthritis patients often excludes those who are obese, but a recent article in the Annals of Internal Medicine suggests that TKR is both effective and cost-effective in obese patients (BMI >40 kg/m2) with end-stage knee osteoarthritis.
Birthday Gatherings Increase COVID-19 Risk
Jun 24, 2021
How risky are family gatherings, birthday parties and informal social gatherings? A cross-sectional analysis suggests that birthdays may be associated with increased rates of COVID-19 infection within households where there is a high COVID-19 prevalence in the population.
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Metanalysis shows no clear association between allopurinol use and a lowered all-cause mortality in gout patients, but the number of studies was small https://t.co/MM0nIjZPbV
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 24, 2021
Italian survey foud 82% of MSK healthcare workers willing to receive COVID-19 vaccine, but only 55% of their rheumatic Dz patients were as willing, even if they perceived they were at risk. Not out of fear or distrust. more education needed https://t.co/nPhhME2dnC
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 24, 2021
66 yoF w/ prurtitic rash, weakness, SOB, hyperpigmented papules over knuckles, periungual hemorrhages, shawl like rash and the Holster sign (lateral thighs). Which drugs would you use:
A. Steroids
B. IVIG
C. MMF
D. Baricitinib
E. Plasmapheresis
https://t.co/IA4qbGri5b
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 24, 2021
Is there a connection between stress and the onset of RA?
https://t.co/Oir9ZV3m7i https://t.co/GTpvTCiMAP
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 24, 2021
Rheumatologist Survey - A man with osteoporosis and recurrent fractures - What should test for ? Phosphorous, testosterone, magnesium or HLA-B27; answer here> https://t.co/TuY1fXAAk5
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 24, 2021
Pain Persists in RA, Even Without Inflammation
MedPage Today
Jun 23, 2021
One-third of patients with rheumatoid arthritis had unacceptably high levels of pain 5 years after diagnosis, often despite low levels of inflammation, Swedish researchers found.
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Better Outcomes with Modern T2T in Pregnancy
Jun 23, 2021
With the expansion of knowledge regarding the safety of newer agents in pregnancy comes the PreCARA study showing that when pregnancy is planned and patients with rheumatoid arthritis (RA) are treated with a modified treat-to-target (T2T) approach, superior outcomes can be anticipated.
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Miss out on something from EULAR?
Check out our daily recaps.
https://t.co/seKFd36te4 https://t.co/O1Of0ThRjS
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
Watch our video on the three new medications for lupus.
https://t.co/IrHEJdpHqK https://t.co/ox7YNU2fFe
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
French Vasculitis registry studied 354 GPA patients- 25% had hypereosinophilia (HE) ≥ 500; mostly male (73%) w/ most skin dz (49%) peripheral neuropathy (32%) & higher BVAS (21 vs 18, p= 0.01): severe HE had more baseline renal dysfunction https://t.co/G4s3CEavL9
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
Enthesitis is a tricky and unclear topic. Dr. Robert Chao ( @doctorRBC ) shares #EULAR2021 learnings.
https://t.co/pZRMZtbJAh https://t.co/kQEKveZFnY
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
What do Rheumatologists Know about XLH? Here's a four question Survey for Rheumatologists on a rare disorder - https://t.co/TuY1fXAAk5
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
FINCH 1 Trial Filgotinib in Rheumatoid Arthritis
The Annals of Rheumatic Disease has published the results of a head-to-head trial showing that the JAK1 preferential inhibitor filgotinib was superior to adalimumab in active RA on MTX.
https://t.co/d501qhArfP https://t.co/YGH5LQDGbs
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
Mouse model of psoriasis; 10 week exposure of western diet (high sugar & fat) induced dysbiosis and increased skin psoriasis & PsA , with increased IL-17A γδ T cells and helper type 17 cytokines. Treatment w/ Abx reduced IL-23 mediated dz. https://t.co/fTCnYiQ3wL
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 23, 2021
Progression from Psoriasis to Psoriatic Arthritis
Jun 22, 2021
The question of whether psoriasis is a state or pre-clinical psoriatic arthritis has been addressed by several studies; with one suggesting that biologic use in psoriasis may aver the future development of psoratic arthritis (PsA).
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FINCH 1 Trial Filgotinib in Rheumatoid Arthritis
Jun 22, 2021
The Annals of Rheumatic Disease has published the results of a head-to-head trial showing that the Janus kinase-1 (JAK1) preferential inhibitor filgotinib was superior to a tumour necrosis factor-α inhibitor (adalimumab) in active rheumatoid arthritis (RA) on methotrexate (MTX).
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Can Focus Score Predict Risk of Lymphoma in Sjogren's Patients?
https://t.co/kBptqUx2XG https://t.co/8y1736Kj8T
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 22, 2021
RheumNow survey question for Rheumatologists - A man with osteoporosis and recurrent fractures should be tested for: phosphorous, testosterone, magnesium or HLA-B27; answer here> https://t.co/TuY1fXAAk5
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 22, 2021
Do gender and racial disparities play a role in PsA patients?
https://t.co/SrMcGOIbu4 https://t.co/QKD0VoK6fC
Links:
Dr. John Cush @RheumNow ( View Tweet)
Jun 22, 2021
From the blog
Rebuttals
Mar 15, 2021
Since the COVID vaccine rollout, more people have been eligible to receive the vaccine. However, not everyone chooses to get one. I have heard many reasons (aka excuses) from my patients who are vaccine hesitant.
Most come from people who are highly intelligent, and claimed that they will receive the vaccine but not yet. While I am not trying to force people to get vaccinated, I wanted to hear their side of the story and also ask that they hear mine.
Recent Podcasts
RheumNow Podcast - Speak Up! (6.18.2021)Jun 18, 2021-
RheumNow Podcast - Best of EULAR 2021 (6.11.21)Jun 11, 2021
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RheumNow Podcast - EULAR 2021 & EULAR-IQJun 04, 2021
EULAR 2021 - Day2dJun 04, 2021-
EULAR 2021 - Day2cJun 04, 2021
Therapeutic Update
Upadacitinib’s Long Term Efficacy and Safety
Sponsored by AbbVie Medical Affairs
Jun 01, 2021
Explore upadacitinib’s long-term efficacy through 3 years in the SELECT-COMPARE trial and dig into data
for the integrated safety analysis across 6 phase 3 studies with up to ~4.5 years of exposure.
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