Recent News
-
Watch Video
This TNR recaps a SpA session from RheumNow Live 2024, with lectures on: Nonradiographic Axial Spondyloarthritis Eric Ruderman, MD; Enthesitis in Spondyloarthritis Lihi Eder, MD; and Future Therapy of Axial Spondyloarthritis Lianne Gensler, MD.
Chào: (Vietnamese: Goodbye/Hello)
In my first blog about self-discovery, I detailed the burnout and why I left clinical practice. In this second blog of the trilogy, I wanted to share encounters with patients as I told them goodbye.
https://t.co/S3YUQGcgxW https://t.co/X5HWUqHyUc
Dr. John Cush @RheumNow ( View Tweet)
ICYMI: Five Takeaways in PsA/SpA at RNL 2024
https://t.co/NypLaqjnlp https://t.co/iRpDHNKMhF
Dr. John Cush @RheumNow ( View Tweet)
Predicting CKD Outcomes in Lupus Nephritis
An observational cohort study suggests that proteinuria levels in lupus nephritis (LN) patients did not predict their histologic class. A multicentre observational study of patients with biopsy-proven LN; either proliferative (PLN) or membranous (MLN) lupus nephritis were compared regarding clinical and laboratory presentation and long-term outcomes. The primary outcome was progression to chronic kidney disease (CKD).
Read Article
ICYMI: Five Takeaways in PsA/SpA at RNL 2024
Continuing with the theme of clinical pearls, the PsA and SpA speakers also provided a wealth of information. Here are my five key takeaways and clinical pearls.
Read Article
Self Acupressure in Knee Osteoarthritis
A clinical trial has shown that self-administered acupressure (SAA) is effective in relieving knee osteoarthritis (KOA) patients.
https://t.co/jwP25u7J0b https://t.co/PH3aOoJaDu
Dr. John Cush @RheumNow ( View Tweet)
ICYMI: How do you manage enthesitis?
https://t.co/8cuKz1Ddpb https://t.co/3KMKQCVDSN
Dr. John Cush @RheumNow ( View Tweet)
50 active RA pts RCT Rx w. either low dose IL-2(n=26), IL-2+TCZ (9) or control (15). All improved clinically by DAS28-ESR, but IL-2 Rx pts had signif proliferation of Tregs, w. decr inTh1, Th2, & Th17 cells. TREG #s correlated w/ ESR drop (r=0.54) https://t.co/1tF63FuXzx https://t.co/M5TWsa6zI4
Dr. John Cush @RheumNow ( View Tweet)
Single center retrospective 173 pts w/ CTD-ILD - 34% Sjogren’s, 30 RA, 25 systemic sclerosis, 6 UCTD, 3% idiopathic inflam myositis, 1,2% MCTD, 0.6% SLE. NSIP most common (60%) inSS & SSc; UIP more common in RA. 6 died, mostly infection https://t.co/IL2tnVDtoQ https://t.co/Ada49Qv5XL
Dr. John Cush @RheumNow ( View Tweet)
'Drug Rediscovery for Rare Immune Mediated Inflammatory Diseases’ - a 6 center consortium will study if JAKi (filgotinib) is effective and safe in 3 rare disorders -- Behcets, inflammatory myositis & IgG4 related disease. https://t.co/2gKCKEl7Ml https://t.co/yTrvFzFUgf
Dr. John Cush @RheumNow ( View Tweet)
SGLT2 Inhibitors Lowers Gout Risks in Type 2 Diabetes
A population-based cohort has demonstrated tha SGLT2i use in gout patients is superior to sulfonylurea therapy in lowering the risk of incident gout and recurrent flares among patients withT2D.
https://t.co/QZ7bt39zEW https://t.co/Wlo9SF0hPF
Dr. John Cush @RheumNow ( View Tweet)
STEP 9 - a, multinational phase 3 RCT studied semaglutide vs PBO in 407 Knee OA (Gr2-3) pts w/ pain >4/10 & BMI >30 (mean 40.3; mean WOMAC 71). At wk 68 SEM > PBO lowering WOMAN pain (-42 v -27; p<.001). Wt loss: 13.7% v 3.2%, respectively. https://t.co/101qML0wQM https://t.co/tG3hk5Wy5E
Dr. John Cush @RheumNow ( View Tweet)
Articular Findings Sarcoidosis:
- Acute arthritis: Lg Jt Oligoarthritis; Loffgrens syndrome (hilar LN, arthritis, E. nodosum)
- Acute > Chronic arthritis
- Chronic arthritis: tenosynovitis, oligo- &polyarthritis, dactylitis, erosions or Jaccouds arthritis
https://t.co/zDLJqsjnbj https://t.co/lo6UIlhka3
Dr. John Cush @RheumNow ( View Tweet)
178 Knee OA pts undergoing Arthroscopic Surgery do not have a higher risk of Total Knee Arthroplasty (33.7% vs 41.9% controls (HR 0.85), nor was there a significant delay or hastening TKA. https://t.co/vKN1Nsjr1n https://t.co/0mb5dJWf6u
Dr. John Cush @RheumNow ( View Tweet)
New Oregon law rebrands Physician Assistants to a new title of “physician associates" (goes into effect 6/6/2024). The title change only applies to PAs and not NPs. The AMA has come out against such change in title, thinking it may confuse patients. https://t.co/oWxNwpIW7U https://t.co/GJC8u0XrRj
Dr. John Cush @RheumNow ( View Tweet)
Pediatric IMID pts have 4 fold mortality. Danish population study of 11,581 pIMID (vs 99K controls), 1.37 million PYs F/U. Dx age 12.6 yrs; 152 pIMID deaths (vs 316) aHR=3.8. +6.9 deaths/100K PYs. Most for GI Dz/CA & lymphoproliferative dz https://t.co/JpGzusLXMH https://t.co/OMtB1z0RmG
Dr. John Cush @RheumNow ( View Tweet)
Self Acupressure in Knee Osteoarthritis
A clinical trial has shown that self-administered acupressure (SAA) is effective in relieving knee osteoarthritis (KOA) patients.
Read Article
Hyperpigmentation from Hydroxychloroquine. From 316 HCQ pts, 26% got hyperpigmentation; delayed onset of 12 mos (6–30mos) after median cum. dose of 108 g. Seen on face (602%), Legs (36%) & hands (20%). Daily sun exposure decrease in the incidence (P=0.02) https://t.co/365qcuIpWE https://t.co/cHO16kDtK3
Dr. John Cush @RheumNow ( View Tweet)
Chikungunya arthritis Metanalysis & good full-read review - 8 studies showing chronic arthritis (CCA) in minority of infected;, polyarticular, looks like RA, few seropositive, few w/ erosions on imaging. CCA may be progressive w/ irreversible damage https://t.co/Da7bKtM6oC https://t.co/OGBbIiGAc5
Dr. John Cush @RheumNow ( View Tweet)
CPPD in seronegative RA? Among 364 RA patients - 73% seropositive & 26% seronegative (n=96). Amongst latter, 18 pt (18.9%) met CPPD-disease criteria. CPPD+ pts were more likely to be older & have Hx of acute episodic arthritis https://t.co/XO0J6Adaa0 https://t.co/3ouUCPshoh
Links:
Dr. John Cush @RheumNow ( View Tweet)
Dawn of CAR-T cell therapy in autoimmune diseases - A review article from the Chinese Medical Journal https://t.co/Qbort9Rsmh https://t.co/wWwTXkZiXj
Dr. John Cush @RheumNow ( View Tweet)
From the blog
One of the first words I was taught by my parents was “chào”. In Vietnamese, you say chào and bow when you greet someone or when you leave as a sign of respect.
In my first blog about self-discovery, I detailed the burnout and why I left clinical practice. In this second blog of the trilogy, I wanted to share encounters with patients as I told them goodbye. While I received great advice when I started practice, no one ever talks about how hard it is to leave.
Read Post
Podcasts
Tuesday Night Rheumatology- Spondyloarthritis Spectrum
Nonradiographic Axial Spondyloarthritis - Dr. Eric Ruderman
Canary In A Coal Mine (4.19.2024)
Vasculitis Faculty Panel Q&A
Poster Hall
