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Best of 2024: Efficacy of Biologics in Patients with Chronic Kidney Disease

A retrospective cohort study of biological disease-modifying antirheumatic drugs (bDMARDs) persistence in rheumatoid arthritis patients with chronic kidney disease, shows the 3 year survival to be under 50% but that all studied biologics were nearly equivalents with regard to safety and efficacy.

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🔍 Vaccine immunogenicity with JAKi treatment Watch Dr. Kevin Winthrop present long-term immunogenicity of an adjuvant recombinant zoster vaccine in patients aged ≥50 years with RA receiving a JAKi. Sponsored by AbbVie Medical Affairs + Health Impact. https://t.co/xh2X6CO9P5 https://t.co/bhcQKRLR2d
Dr. John Cush @RheumNow (  View Tweet)
Best of 2024: Consensus Statements on Vitamin D https://t.co/K11CekojNy https://t.co/LTYLrYeqFD
Dr. John Cush @RheumNow (  View Tweet)
Best of 2024: Inadequate Zoster Vaccination in Immunocompromised Patients https://t.co/P2S6byNmgI https://t.co/owVSpCRL89
Dr. John Cush @RheumNow (  View Tweet)
Best of 2024: Pain Reduction with Methotrexate in Knee Osteoarthritis https://t.co/1zG2tWQk1f https://t.co/WvTkZ3q2IK
Dr. John Cush @RheumNow (  View Tweet)

Best of 2024: ASLeap: Higher Dose Secukinumab in Ankylosing Spondylitis

Ankylosing spondylitis (AS) patients not responding to usual dosing with secukinumab (150 mg) after 16 weeks were dose escalated to secukinumab (SEC) 300 mg, but failed to show improvement by week 52.

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Best of 2024: Consensus Statements on Vitamin D

The “Controversies in Vitamin D” International Conference has published their proceedings on vitamin D metabolism, assessment, actions, and supplementation. Interestingly, optimal levels of 25-hydroxy vitamin D (25(OH)D) are still being debated.

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Sarcoidosis is biopsy supported not proven” -Dx is clinical with broad ddx. -Assess organ involvement in all pts. -Whole body PET can help assess disease activity (not in CNS disease) -MR brain with pituitary cuts helpful in CNS sarcoid. #ACR24 @ACRheum @RheumNow… https://t.co/Ka1cHtFOqj

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RheumNow Live 2025: Feb 8-9, Dallas, TX! 🔬 Don’t miss top experts on Psoriatic Disease: ➡️ A. Ogdie: Preventing PsA ➡️ A. Kavanaugh: Biologic Therapies ➡️ K. Gordon: Head-to-Head Studies Register now! https://t.co/9qnqtpkwpT https://t.co/95TGS56vyA
Dr. John Cush @RheumNow (  View Tweet)
Best of 2024: Lung Cancer in Rheumatoid Arthritis and Interstitial Lung Disease https://t.co/Sd3H5Tzhtf https://t.co/guXzL5bc6R
Dr. John Cush @RheumNow (  View Tweet)
Best of 2024: Analgesic Prescribing in Patients with Inflammatory Arthritis https://t.co/iQrBVzWaI8 https://t.co/Rx86Q57oEZ
Dr. John Cush @RheumNow (  View Tweet)
Bah Humbug Vitamin D (12.20.2024) https://t.co/Mjuk6buRsX https://t.co/aX8cetkbWc
Dr. John Cush @RheumNow (  View Tweet)

Best of 2024: Inadequate Zoster Vaccination in Immunocompromised Patients

A VA study of shows that recombinant zoster vaccine (RZV) vaccination in immunocompromised patients or those receiving immunosuppressive medications is insufficient, given these are high risk individuals.

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Best of 2024: Pain Reduction with Methotrexate in Knee Osteoarthritis

The Annals of Internal Medicine reports that oral, low dose, weekly methotrexate significantly reduced knee osteoarthritis pain, stiffness, and function in a randomized controlled trial.

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If high +ANA and NO #rheumatic #disease LOOK đź‘€ at #LIVER #Autoimmune #hepatitis And #alcoholic #liver #dx #ACRBest #ACR24 @rheumnow abst#0627 https://t.co/0bwfgNnB0e

Dr. John Cush @RheumNow (  View Tweet)

To Behcet’s or not to Behcet’s? -Aphtous ulcers have unique features(broad ddx) -Oral+Genital ulcers=CAP not necessary BD. -Pathergy test ⬆️specific and not limited to skin! -Pulmonary arterial aneurysms=almost pathognomonic. -Do not get confused by HLAs. #ACR24 @RheumNow… https://t.co/3nWgILNVYw

Dr. John Cush @RheumNow (  View Tweet)

A Fibroblast Renaissance Dr. Andrea Fava at the 2024 ACR Convergence meeting in Washington, DC. https://t.co/GQXWkqMkIW https://t.co/W6UXT4HCeg
Dr. John Cush @RheumNow (  View Tweet)
Tocilizumab Efficacy in Giant Cell Arteritis Phenotypes A Spanish Collaborative Group study of Tocilizumab (TCZ) in Giant Cell Arteritis (GCA) demonstrated high efficacy regardless of the different vascular phenotypes treated. https://t.co/8wvSy8555Z https://t.co/vaGt1AylBr
Dr. John Cush @RheumNow (  View Tweet)
Nailfold video-capillaroscopy (NVC) study of 76 dermatomyositis (DM) pts - 74% had anomalous NVC patterns (diminished density, abnl morphology). NVC abnl pts had more Raynaud's, and cluster 1 were more likely to develop ILD.https://t.co/AsZ9CU2TZU https://t.co/TP1TMqotqi
Dr. John Cush @RheumNow (  View Tweet)
41 "Rhupus" pts were compared to 160 SLE and 709 RA pts. Rhupus pts have a younger onset age than RA (P=0.032), but older than SLE (P=0.008). ~20% initially presented w/ SLE Sxs. Rhupus commonly has ILD, hyperglobulinemia & Lab abnormalities (61%), but seldom renal or CNS dz… https://t.co/m7VL6HHdUN https://t.co/i3knGVQYvj
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