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Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.
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The ACR COVID-19 Vaccine Clinical Guidance was originally published on February 8, 2021 and updated on March 4, 2021. On April 28, 2021, new recommendations were added regarding mycophenolate, methotrexate, acetaminophen, and NSAID timing considerations,
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A metanalysis showed that while adverse events (AEs) are common when methotrexate is used in rheumatoid arthritis or inflammatory arthritis patients, serious AEs ranged from 2.1 to 9.5% and drug discontinuations ranged from 6.7% to 15.5%, mostly due to gastrointestinal events.
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A large patient cohort study suggests that the mean diagnostic delay (DD) in European axial spondyloarthritis (axSpA) patients is 7.4 years, moreso in women and younger patients.
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A phase III trial assessing the efficacy and safety of tofacitinib in adults with with active ankylosing spondylitis (AS) shows that JAK inhibitiion was superior to placebo in a 48 week study.
Dr. John Cush
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Tuesday Night Rheumatology from April 20
#RNL21: Update - Global Rheumatology Alliance Registry
https://t.co/QQY80evw00 https://t.co/jkBmAP09xU
Dr. John Cush
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New podcast up! Uppers and Downers.
https://t.co/kt63YryptW
Dr. John Cush
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News Feature: Predictors of Methotrexate Toxicity
https://t.co/HjszwdaxVR
Dr. John Cush
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Did you miss this week’s Tuesday Night Rheumatology? Listen to the playback.
https://t.co/yTYkeSY7my
Dr. John Cush
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RheumNow Podcast is Up! – with news of Uppers and Downers. Read about Vaccine success, CKD gout prophylaxis, TOFA in AS & too much IL-17 inhib can be a problem https://t.co/kt63YrQ0Sw Listen iTunes> https://t.co/FHJv01AAbC or Android SoundCloud>>https://t.co/IyYvjkWUc1
Dr. John Cush
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Metanalysis of 9 studies, and 1132 lupus pregnancies shows that hydroxychloroquine treatment significantly reduced the risk of preeclampsia (OR 0.35), pregnancy hypertension (OR0.41)and prematurity (OR 0.55), but no effect on rates of HELLP, DM, Ab https://t.co/P9MXjDpuiO
Dr. John Cush
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News Feature: Golimumab Effective in non-radiographic Axial Spondyloarthritis
https://t.co/KWqQLHWIiB
Dr. John Cush
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Check out this issue of Arthritis & Rheumatism from 1961. In addition to the great article by Charles Ragan on the "History of Rheumatoid Factor" (pg 571), thumb thru the pages to see the Ads and what rheumatology looked like 60 years ago. https://t.co/Ed9watO3Dw
Dr. John Cush
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CDC study shows that adults >65yrs who are fully vaccinated (w/ Pfizer or Moderna) showed 94% drop in COVID-19 hospitalization (64for among partially vaccinated adults) https://t.co/iJrbiNJg2r
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Will you be attending our Tuesday Night Rheumatology series? Events and topics linked below.
Sign up today!
https://t.co/ugGaPvBsLD
Dr. John Cush
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Gout Prophylaxis in patients with severe CKD? Metanalysis of 33 studies suggests 1) lack of good data guidance; 3) Colchicind is associated w/ toxicity w/ CKD (neuromyopathy, rhabdomyolysis; 3) anakinra - works, expensive, little/no toxicity https://t.co/VhI0wRC0VO
Dr. John Cush
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News Feature: Search Tofacitinib in Ankylosing Spondylitis
https://t.co/cTRvB3cvsh
Dr. John Cush
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Get a Clue - to the Dx of FM
https://t.co/LRC7e8PPla
Dr. John Cush
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News Feature: Psoriatic Pregnancies Pose Risks to the Mother, Not Child
https://t.co/kZE2yLEvm7
Dr. John Cush
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News Feature: Dual IL-17 Targeting is Effective but has More Candidiasis
https://t.co/uDNx65PcC4
