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New Side Effect From mRNA COVID Vaccines?

MedPage Today Apr 20, 2021

Herpes zoster reactivation -- a.k.a. shingles -- following COVID-19 vaccination in six patients with comorbid autoimmune/inflammatory diseases may be a new adverse event associated with the Pfizer/BioNTech mRNA vaccine, suggested a new report.

Article

Raynaud and Microvascular Complications with New Migraine Meds

Jack Cush, MD Apr 20, 2021

A new study of calcitonin gene-related peptide (CGRP) antagonists for migraine headaches found that a small subset manifested Raynaud phenomenon and other had microvascular complications, suggesting that CGRP antagonists should be used in caution in patients with Raynauds.

Article

Dr. Charles Christian of HSS Honored

Jack Cush, MD Apr 19, 2021

In the current issue of Annals of Rheumatic Disease, Dr. Peggy Crow honors the life and career of one the great, historic rheumatologists of all time: Dr. Charles Christian. For those interested in the history of rheumatology, mentoring and leadership, this is a good read. For those interested in leading a truly good life, and being a real role model, this is a must read.

37 RA, 28 PsA & 20 AS pts in remission/LDA x 6 mos enrolled in DMARD spacing. Joint flares seen in 13.5% RA, 21.4% PsA & 20% axSpA pts but 5 more PsA patients had skin flare. PsA had lower persistence 61% (vs RA 87% & 80% AS) due to skin flares https://t.co/d1rMLTXSQs https://t.co/fNNSofWxgv

https://bit.ly/3gmrH4R

News Feature: Dr. Charles Christian of HSS Honored In the current issue of Annals of Rheumatic Disease, Dr. Peggy Crow honors the life and career of one the great, historic rheumatologists of all time: Dr. Charles Christian. https://t.co/UYOcR0QPc4 https://t.co/ML4snlVumB

https://bit.ly/3dwOngU

55 pts w/ Multi-joint osteonecrosis (>2 jts).( SLE 29%, ALL 11%, HIV 9%, EtOH 4%). Mean cumulative steroid dose >30 g over 5 yrs. Predictors of MJON was cumulative oral steroid dose (3.2% incr per 1000 mg. MJON risk incr 12 X w/ 2nd risk factor https://t.co/dqTPh2PV8V https://t.co/HTrSnZSefK

https://bit.ly/3gyTP57

Study of 207 Pediatric pts treated w/ Rituxan (for Rheum, Cancer, CNS, Renal dz) and 40% developed hypogammaglobulinemia post-RTX; hypo-IgG Pre-RTX 28.7% to Post RTX 42.6%, p=0.009; low IgG levels had higher risk of serious infx (OR 2.3) https://t.co/b91rPYgVV2

https://bit.ly/3dsAz7g

A Patient-Centered Exploration of Axial Involvement in SpA Sponsored by Novartis Medical Affairs Listen to a medical expert differentiate axial involvement within the spectrum of spondyloarthritis. https://t.co/o2q5pTP3WD https://t.co/GiqdIqitMB

https://bit.ly/39P4e8t

Great reminder of from Dr. Kathryn Dao, @KDAO2011 from #RNL2021 Caution! Verrucous LE can simulate skin cancer! Both can be found in photosensitivity areas! #RheumNow

Shared from #RNL2021 from @uptoTate "Absence of proof of an effect is not proof of absence of an effect!" Dr. Kavanaugh's sage reminder for the day"

Tonight! Join us for Tuesday Night Rheumatology with Dr. Philip Robinson and Dr. Iain McInness. We'll discuss highlight sessions for RheumNow Live 2021 #RNL2021 https://t.co/oJ4xYKLrj4 https://t.co/K1OQz40aZ1

https://bit.ly/3ecHkJG

News Feature: Planes, Trains and COVID Distancing MMWR reports the risk of acquiring an infection with SARS-CoV-2 is reduced 23% to 57% when the middle seat was vacant (compared with full aircraft occupancy). https://t.co/tGs9GopeGu https://t.co/ZRMltTpYgW

https://bit.ly/2Q136Ik

News Feature: Broadalumab Efficacy in Axial Spondyloarthritis Broadalumab, an anti-interleukin-17 receptor A monoclonal antibody, is FDA- approved for use in adults with plaque psoriasis; but a recent trial shows it to be effective in patients with axSpA. https://t.co/V0zKbFMgy7 https://t.co/U5CGXUF7Sw

https://bit.ly/3naAEzF

Dual seropositivity with RF/ACPA autoantibody higher titers were strongly associated with prevalent RA-ILD (OR 2.90; developed in 3.7%). ILD more likely with high titer RF (HR 3.4) than high titer CCP (HR 1.9). https://t.co/ebvJjatQSw

https://bit.ly/3anLgpw

304 pts w/ Knee OA studied by MRI and atorvastatin 40 mg qd was no better than placebo in reducing cartilage volume loss, BM lesions, pain, or function over 2 years https://t.co/MIdIFQ9qzs

https://bit.ly/3n6bTof

Serious problem! Pulmonologists uniformly believe that MTX causes and/or worsens ILD. MTX causes hypersensitivity pneumonitis, not ILD. RA, lupus DM, PSS cause ILD and they may need MTX to manage their disease. Do your own research, look at this paper to start. https://t.co/DHC5ikhCf6

https://twitter.com/UTSWRheum/status/1382700690410246151

There's a special, deep hell for insurers/PBM's that give patients a hassle over paying for a cheap drug like methotrexate. And these days it's looking like it's going to be very, very crowded.

Another @preventiveneur1 paper just published. @tomrptaylor looked at demyelinating events reported in people taking anti-TNF in the BSRBR. We found that these events are uncommon in people with underlying rheumatological disease https://t.co/qCaF6YMLAh

Demyelinating Events Following Initiation of Anti-TNFα Therapy in the British S…

#RNL2021 coverage from @doctorRBC "Biosimilars are on their way. Coming to you in 2024! They will most likely be cheaper for insurance companies, but will they be cheaper for patients? " #RheumNow

Join us for Tuesday Night Rheumatology with Dr. Philip Robinson and Dr. Iain McInness. We'll discuss highlight sessions for RheumNow Live 2021 #RNL2021 https://t.co/oJ4xYL32aC https://t.co/Eix01GlWoj

https://bit.ly/3ecHkJG

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All News

New Side Effect From mRNA COVID Vaccines?

Raynaud and Microvascular Complications with New Migraine Meds

Dr. Charles Christian of HSS Honored

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