RheumNow Podcast – Uppers and Downers Save

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

1. MMWR CDC study shows that adults >65yrs who are fully vaccinated (w/ Pfizer or Moderna) showed 94% drop in COVID-19 hospitalization (64% for among partially vaccinated adults)  https://t.co/iJrbiNJg2r

2. Gout Prophylaxis in patients with severe CKD? Metanalysis of 33 studies suggests 1) lack of good data guidance; 3) Colchicine is associated w/ toxicity w/ CKD (neuromyopathy, rhabdomyolysis; 3) anakinra - works, expensive, little/no toxicity https://t.co/VhI0wRC0VO

3. Analysis of Taiwans National Health Insurance Database, shows from >4.5 million children (<18yrs), 23% received steroid burst < 14 days (URI, allergies, asthma) and shows higher 30 rates of GI Bleed (IRR 1.4), Sepsis (2.02), & pneumonia (2.19) https://t.co/ReuNP1C8ww

4. Hydroxychloroquine related hyperpigmentation appears as Blue or black discoloration of skin or mucosa, occurs in 7-30%; Recent report says ~5%; Risk factors include steroids, bruising, anti-coagulants and trauma - theyr slow to resolve if you D/C  https://t.co/aTSBopIEQN

5. Golimumab Effective in non-radiographic Axial Spondyloarthritis 

6. Little Effect with Multimodal Treatment of CMC1 Osteoarthritis 

7. Dual IL-17 Targeting is Effective but has More Candidiasis

8. Tofacitinib in Ankylosing Spondylitis

9. ACR Updates COVID-19 Vaccine Guidance- April 2021   

10. Tuesday Nite Rheumatology – Highlights from RNL 2021 – Advance in RA 

11. BACK TALK – Rheums, got a Rheumatology question or case for Jack Cush? Record it here and we'll feature it on an upcoming podcast. Tell us your name and where you practice rheumatology.