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As data continue to emerge about a multi-system inflammatory disorder in children apparently connected to COVID-19, evidence is growing that this is not your typical Kawasaki disease.
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Annals of Rheumatic Disease reports on an analysis of lupus (SLE) patients that shows COVID-19 infection rates were similar between those lupus patients who were taking hydroxychloroquine (HCQ) and those not taking HCQ.
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Last night's Tuesday Nite Rheumatology featured Dr. Joan Merrill (OMRF). In her lecture, "What does COVID-19 have to do with lupus?", she discusses the pathogenesis of lupus, and specifically thrombotic microangiopathy, complementopathies, catastrophic lupus syndrome and the potential overlap with the vascular pathology seen with COVID-19 infection.
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It's Nurses Week and time to reaffirm our reverence for nurses. Dr. Jack Cush gives a video testimonial to the dedication, dependability and excellence Nurses bring to patient care. God Bless our Nurses!
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MMWR reports that after attending a 2.5 hr choir practice with one COVID+ symptomatic person, 87% of the choir developed COVID 19; 3 were hospitalized, and two died.
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The ACR has published the 2020 guidelines on the management of gout that includes strong recommendations favoring treat‐to‐target management and starting urate lowering therapy (ULT) for patients with frequent flares, radiographic damage or tophi due to gout.
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The EXCEED study was a head-to-head trial of secukinumab (SEC) versus adalimumab (ADA) as first-line monotherapy in psoriatic arthritis (PsA) patients; this 52 week trial showed that while SEC failed to achieve clinical superiority over ADA, SEC treated patients demonstrated higher
T. Scott Diesing, M.D.
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New axioms in the time of #COVID-19
1. Always assume every patient may have COVID-19
2. Always assume your Zoom camera is on.
3. Always assume your microphone is live.
4. Always assume something will be fundamentaly different next week.
@medicalaxioms #covid4MDs
Dr. John Cush
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Tuesday Nite Rheumatology Grand Rounds by Dr. Joan Merrill (OMRF) on "What Does COVID-19 Have to do with LUPUS". Watch it here>>https://t.co/q5Om4CQAnP or listen on iTunes or here>> https://t.co/yJWsmds0cg
Dr. John Cush
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Interview w/ Private Practice Rheums on Covid - Drs. Herb Baraf and Danny Ricciardi. DC & Brooklyn Docs wrangle technology, Telehealth, Return to normal, the future and more. Watch it here>> https://t.co/TaMbiF9MLC or listen on iTunes or here>> https://t.co/G7sR23bwLW
Dr. John Cush
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God Bless our Nurses! Happy Nurse Week! https://t.co/5TRitXfvpu
Dr. John Cush
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Metanalysis shows Type 2 DM associated with >2-fold increased risk (aHR 2.25) of severe liver disease (NAFLD); a more modest risk w/ obesity (HR 1.20); other risk variables - low HDL, high triglycerides & hypertension were independently associated https://t.co/uUdARZYkqG
Dr. John Cush
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Hungarian population study of incident SLE (4503 pts) and treated SLE pts (2582) finds standardized mortality ratio elevated in SLE (1.63 and 2.09). cause of death differed only for infection with infection-related deaths more common in SLE. https://t.co/IEkfShjCt1
Dr. John Cush
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Study of 274 women with axSpA shows that longer time to pregnancy (TTP) was associated with older age, nulliparity, and longer disease duration. https://t.co/GznVvnPAwO
Dr. John Cush
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Why are more MEN (severely?) affected in COVID-19? Men have higher levels of circulating ACE2 (unrelated to ACEi or ARB HTN meds) based on a Biobank study of 1485 men, 537 women. ACE2 is found in lungs, heart, kidneys, vessels & testes https://t.co/CWXevTNYWm
Dr. John Cush
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A new feature of COVID-19; "Covid toes" manifest as multifocal, asymmetric, erythema, ecchymoses, ischemic changes that blister or appear vasculitic. The toes, heel and soles can be affected. Healing in 12-20 days. https://t.co/Isqn9ebnQj
Dr. John Cush
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Subanalyses of Mobility and Monarch studies show that #RA patients with highest tertiles of IL-6 (and CRP) had more disease activity, more Xray damage and better responses (less Xray change) to Sarilumab (vs Adalimumab or MTX). https://t.co/5mTePETFAQ
Dr. John Cush
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1194 participants in Osteoarthritis Initiative shows 10 yr risk of incident Xray Knee OA was not increased by long term sitting, low-moderate physical activity (adjOR 0.69; 0.48-1.01) or strenuous phys activity (aOR 0.75; 0.53-1.07) https://t.co/7pCOwLpscr
Dr. John Cush
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"There's a rule in acting called "Don't play the result." If you have a character who's going to end up in a certain place, don't play that until you get there. Play each scene and each beat as it comes. And that's what you do in life: You don't play the result."
-Michael J. Fox
Dr. John Cush
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Why are more MEN (severely?) affected in COVID-19? Men have higher levels of circulating ACE2 (unrelated to ACEi or ARB HTN meds) based on a Biobank study of 1485 men, 537 women. ACE2 is found in lungs, heart, kidneys, vessels & testes https://t.co/CWXevTNYWm
