RheumNow Week in Review - 29 July 2016

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Dr Jack Cush reviews this week's highlights from RheumNow.com.

Novel Rise of Combined Dermatology-Rheumatology Clinics

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Rheumatology News has a novel online report about combined rheumatology-dermatology clinics.  In the last several years, there have been a few of these in operation (Boston, Chicago, Rhode Island).

RheumNow Week in Review – 22 July 2016

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From tofacitinib developmental trials in RA and psoriasis and adherence to T2T in early RA to a rheumatology pearl about dapsone and much more, here are the highlights of what you may have missed on RheumNow.com this week.

Little Evidence Favoring the Health Benefits of Vitamin D

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Vitamin D certainly plays a pivotal role in bone health and immune function.

DEXA Still Needed While on Bisphosphonates

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Reuters reports that a study of 6629 Canadian women with osteoporosis taking bisphosphonates found that nearly one in five had a decrease in bone density while on medication. (Citation source: http://buff.ly/2afb7nj) 

Prevalence of Spondyloarthropathy in Fibromyalgia

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With the introduction of ASAS criteria for the diagnosis of axial and peripheral spondyloarthropathy, there has been a debate about whether patients with fibromyalgia (FM) could be mistaken for a spondyloarthropathy, or vice versa.

RheumNow Week in Review – 15 July 2016

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Dr. Jack Cush reviews highlights from this week's rheumatology news on RheumNow.com.

Gut Microbiome Shapes Risk and Response in Rheumatoid Arthritis

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In Genome Medicine, Mayo Clinic researchers investigated a cohort of rheumatoid arthritis (RA) patients, their relatives and a healthy control group analyzing the gut microbiome vial16S ribosomal DNA analysis of fecal samples.

Academic Female Physicians Paid Less than Male Counterparts

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Female academic physicians at public medical schools had lower average salaries than their male counterparts, a disparity that was only partly accounted for by age, experience, medical specialty, faculty rank and other factors, according to an article published online by JAMA Internal Medicine.

EULAR Revised Recommendations for Fibromyalgia

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The European League Against Rheumatism (EULAR) has published updated recommendations on the management of fibromyalgia in the Annals of the Rheumatic Diseases (Citation source http://buff.ly/29I7e8C). 

Vagal Stimulation Improves Cytokine Production and Rheumatoid Disease Activity

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PNAS has published a study wherein an inducible “inflammatory reflex” delivered by vagus nerve stimulation was shown to inhibit the production of tumor necrosis factor (TNF), an inflammatory molecule that is a major therapeutic target in an animal model of rheumatoid arthritis (RA).

Patient Reluctance to Take Bisphosphonates

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The NY Times reports that millions of Americans with osteoporosis are driven to stop or not take bisphosphonate therapies over the fear of exceedingly rare side effects - osteonecrosis of the jaw (ONJ) and atypical femoral fractures (AFF).

Adalimumab Approved for Uveitis

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Autoimmune ophthalmic disease is a frequent challenge to rheumatologists from both a diagnostic and therapeutic perspective. Approved therapies are limited and have only been infrequently or comfortably utilized by rheumatologists and autoimmune ophthalmologists.

RheumNow Week in Review – 1 July 2016

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Dr. Jack Cush reviews highlights from the news and social media in the past week on RheumNow.com

Checkpoint Inhibitors Causing Arthritis

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A recent report from Johns Hopkins, published in the Annals of Rheumatic Diseases, describes 13 cancer patients treated with the immune checkpoint inhibitors, ipilimumab or nivolumab, who developed inflammatory arthritis and sicca syndrome.

Tocilizumab in Pregnancy

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Tocilizumab is currently listed as a Category "C" pregnancy risk based on limited pre-clinical (animal) data that was negative.

Cancer Risk Lower with TNF inhibitors in Rheumatoid Arthritis

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Since the introduction of TNF inhibitors nearly 20 years ago, concerns over a potential associated cancer risk have abounded. The recent ACR RA treatment guidelines have addressed this recently, stating that patients with any solid tumor cancer or risk thereof should be treated as if they ha

Biologics and Fatigue in Rheumatoid Arthritis

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Researchers from Bristol, UK have published a Cochrane review studying the effects of biologic therapies on fatigue.

Hyperuricemia Increases Risk of Diabetes, Death and CV Disorders in Hypertensive Patients

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While hyperuricemia is linked to gout and many of the elements that make up the metabolic syndrome, it's not so clear that hyperuricemia is an independant risk factor for hypertension, diabetes, cardiovascular outcomes, etc.

Family History and Rheumatoid Arthritis

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