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Tic-Borne Disorders Causing Chronic Arthritis?

Jack Cush, MD

Findings from a population based cross-sectional study suggests that while up to 20% of patients have antibodies to tick-borne exposures, only a minority reported musculoskeletal symptoms. 

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New Year's Resolutions (1.5.2024)

Jack Cush, MD

Dr. Jack Cush imparts his new New Year's Resolutions for 2024 and also reviews the news and journal reports from the past week on RheumNow.com.

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RheumNow Podcast – Bill of Rights (12.15.2023)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. Two major reports on fatigue and fibromyalgia misfired, and "ankylosing spondylitis" is sent to the Rheumatology dead word cemetery. 

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ICYMI: ACR Plenaries: Changing the Practice of Rheumatology

Kathryn H. Dao, M.D.

Over the years of navigating the annual meeting, I found the sessions with the most impact to my practice were the Plenary Sessions. During these sessions, the latest research is presented, new ideas are floated, and old myths debunked. Here are the top ACR2023 Plenary abstracts I found impactful for my practice.

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CBT or Naltrexone in Fibromyalgia (12.8.2023)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.  Be sure to catch the early registration break for 2024 RheumNow Live.

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Is MTX Safe in the Elderly? (12.1.2023)

Jack Cush, MD

Dr. Jack Cush reviews this past week's news and journal reports from RheumNow.com. Good news is that nearly 99% of adult rheumatology positions matched! But the challenge is that 45% of pediatric fellowship programs and 39% of pediatric rheum slots were unfilled in the 2024 NRMP match.

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Day 2 Report - ACR Plenaries: Changing the Practice of Rheumatology

Kathryn H. Dao, M.D.

Over the years of navigating the annual meeting, I found the sessions with the most impact to my practice were the Plenary Sessions. During these sessions, the latest research is presented, new ideas are floated, and old myths debunked. Here are the top ACR2023 Plenary abstracts I found impactful for my practice.

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Incidence, Microbiological Studies, and Factors Associated With Prosthetic Joint Infection After Total Knee Arthroplasty

Jack Cush, MD

A study of nearly 80,000 US veterans who underwent primary knee joint arthroplasty (TKA) showed  the incidence of prosthetic joint infection (PJI) was highest in the first 3 months and remained elevated through 12 months compared with 12 months or more after surgery.

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Late Should Not Be Less (11.3.2023)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal reports and regulatory approvals from the past week on RheumNow.com.

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H. Zoster Subunit Vaccine Efficacy with JAK Inhibitor Therapy

Jack Cush, MD

JAK inhibitors are known to increase the risk of herpes zoster infections between between 3-5 fold.  Two recent reports suggest variable efficacy when JAK inhibitor (JAKi) treated patients are vaccinated with the recombinant herpes zoster subunit vaccine (RZV). 

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Sleep Apnea Smart Watches (10.13.2023)

Jack Cush, MD

Dr. Jack Cush reviews the news, journal reports and regulatory approvals from this past week on RheumNow.com.

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Large French study on infection risk of PsA biologics 12k pts over 6 years When compared to Humira, only Enbrel and Stelara had lower infection risk Concurrent steroid use associated with increased infection 1.85HR @RheumNow #ACR23 Abs#2566 https://t.co/Os1esuodfl
Robert B Chao, MD  ( View Tweet)
#Infection rates are equal in #RWD #real #world #data using #biosimilars compared to previous use of #originators. BC database #0970 #ACR23 ⁦@RheumNow⁩ ⁦@ACRheum⁩ #arthritisresearchcanada #ARC https://t.co/eVSPgVfmQG
Janet Pope  ( View Tweet)
Abst #1584 TMP-SMX⬇️PJP ⬇️SIE,⬇️outpt infx in GPA on RTX. 919 patients: 31% had TMP-SMX, 40% on pred >20 mg/day followed median 496 days. SIE (aHR 0.5, 95%CI 0.3-0.8), outpt infx (aHR 0.7, 95%CI 0.5-0.9), & PJP. Thirteen PJP (all not on TMP-SMX). #ACRbest #ACR23 @rheumnow

TheDaoIndex KDAO2011 ( View Tweet)

To remind us. Glory be! GLORIA a #RCT in elderly active #RA: MTX+10 mg daily #prednisolone which was better than MTX alone. But more infections and no comparison of inexpensive Rx such as adding #HCQ. Still debated as to benefit vs risk of this strategy @RheumNow #ACR23 @ACRheum https://t.co/slOmESbIOW

Janet Pope  ( View Tweet)

Ab#0848 @RheumNow #ACR23 Biomarkers to Differentiate Flare from Bacterial Ifn in SLE CD14 and CD64 modest increase in infections v flare, better than IL-6 and MRP8/14 One marker not enough to differentiate, but in combo w/ complements, procal, dsDNA improves composite scores https://t.co/MeMYbkMTQH
Eric Dein  ( View Tweet)
To finish the #ACR23 Review Course, one of my favourites: the erudite @LCalabreseDO on the complicated web between viral infections and autoimmunity. Complex interactions both ways. Isn't the immune system amazing? (& ref the @CleClinicMD service led by @CCalabreseDO) @RheumNow https://t.co/spLQQfBVdr
David Liew drdavidliew ( View Tweet)
A masterclass by @LCalabreseDO on the management of viral infections and rheumatic disease. Don’t forget to screen for HBV, HCV, HIV prior to immunosuppressive treatment #ACR23 @RheumNow https://t.co/psLXSuhnHk
Dr. Antoni Chan  ( View Tweet)
ID testing for pts with inflammatory eye disease: syphilis, TB, Lyme (where appropriate). Low yield is toxoplasma, toxocara and viral dz - Dr L Kopplin #ACRReview @RheumNow #ACR23 https://t.co/UyQ8Bc2cEy
TheDaoIndex KDAO2011 ( View Tweet)
H. Zoster Subunit Vaccine Efficacy with JAK Inhibitor Therapy Two recent reports suggest variable efficacy when JAK inhibitor (JAKi) treated patients are vaccinated with the recombinant herpes zoster subunit vaccine (RZV). https://t.co/QEPQJkfSjE https://t.co/pFk2mF22ex

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Dr. John Cush RheumNow ( View Tweet)
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