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Alpha-1-Anti-Trypsin-Fc Fusion Protein Ameliorates Gouty Arthritis
Gout is the most common inflammatory arthritis affecting adults and, probably, one of the most underestimated.
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Safety of Colchicine in End Stage Renal Disease
Colchicine toxicity has been linked to renal function and it has generally been advised to adjust colchicine dosing in patients with renal insufficiency.
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The EULAR 2015 Report - Wednesday
EULAR 2015 started the afternoon of Wednesday June 10th.
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Is Ultrasound Changing Rheumatology Practice?
The recent inclusion of ultrasound in the classification criteria of various rheumatic diseases, such as polymyalgia rheumatica and gout, implies this imaging technique is not onlyuseful as a valued diagnostic tool for individual cases, but also on a larger scale, it will improve doctors' ability to
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Allopurinol Reduces Mortality in Gout
CVD risk is significantly augmented in gout. Choi and coworkers studied this issue using a UK general population database using an incident user cohort study with propensity score matching.
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DECT Evidence of Urate Deposition is Associated with X-ray Damage in Gout
Dalbeth and coworkers studied 92 patients with gout and using DECT scanning have shown those with urate deposition on DECT were 8.5-fold more likely to have erosive disease on plain radiographs.
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Prevalence of gout
Lancet article on the increasing prevalence of gout shows a rate of 2.5% in the UK that has increased 67% in the last 15 years.
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CKD is a gout risk factor
Impaired renal function is a known primary contributor to hyperuricemia and risk of gout.
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Night-time Gout Onset is Not Related to Alcohol or Purine Intake
Gout's often told tale of a nocturnal rapid onset and dramatic pain provoked by a bed sheet, is studied in detail by Choi and the Boston online gout study. This report shows that more than half the attacks occur late night and are unrelated to alcohol or purine intake.
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