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RA,hand,elderly,active

Malnutrition and Quality of Life in Elderly RA Patients

Jack Cush, MD

Rheumatoid arthritis (RA) imparts a significant disabilty and quality of life (QoL) limitations worsened by aging, but also by malnutrition.

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RheumNow Podcast – Jack of All Subspecialties (10.1.2021)

Jack Cush, MD

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com

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cardiac2.jpg (keep)

Early Diastolic Dysfunction in Premenopausal Women with RA

Jack Cush, MD

A two-dimensional/Doppler echocardiography of rheumatoid arthritis (RA) detected premature, clinically quiescent diastolic function.

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RheumNow Podcast – I Wanna New Drug.V2 (9.24.2021)

Jack Cush, MD

Almost three years ago to the day, I did a podcast entitled, "I wanna new drug." As I go over this week's podcast, I want to say it again. I want a new drug safe enough to use during pregnancy, for PMR, for GVHD, and more. I'm going to cover these, and other topics including lupus, COVID breakthrough infections, and statin use and the risk of RA, as I review the news and journal articles from the past week on RheumNow.

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arm,muscle,weak

High Comorbidity Rates with Inclusion Body Myositis

Jack Cush, MD

Inclusion body myositis (IBM) patients tend to be older than those with idiopathic inflammatory myositis (IIM), but the scope of disease beyond their myositis is not appreciated.

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RheumNow Podcast – Do More DMARDs Mean More Switching? (9.17.2021)

Jack Cush, MD

Smartphones and diet; COVID-19 and the numbers - reassuring or not, and what about masks?; and do more drugs mean more switching, less persistence, and patient adherence goes up...or down? All this and more news and journal reports in this week's episode.

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infection pneumonia

Pneumocystis Often Lethal in Dermatomyositis

MedPage Today

Patients with dermatomyositis who were positive for a myositis-specific antibody had a much higher incidence of and mortality associated with Pneumocystis jirovecii infection than patients with other antibody-negative idiopathic inflammatory myopathies, Chinese researchers found.

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ACR Comments on JAK Inhibitors and FDA Announcement

ACR

Following is a statement from ACR President David Karp, MD, PhD, on JAK inhibitors and FDA drug safety communication.

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Catastrophic Still's dz occurs early; compares 20 AOSD w/ organ failure vs 40 AOSD without. CAT-AOSD had shorter Dz duration, earlier Rx need; risks: younger; splenomegaly, liver, cardiac,lung involvement; ferritin level, no arthralgia https://t.co/8WIMd0JxZr

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Dr. John Cush RheumNow ( View Tweet)

US Preventive ServTask Force has advised that adults >60 yrs should NOT take daily preventative aspirin without a no hx of MI/CVD risk (the GI risks outweigh CV benefit). If 40-59 yrs, discuss w/ their MD if ASA would be beneficial https://t.co/jfqnBjwLLn

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Dr. John Cush RheumNow ( View Tweet)

Anakinra appears to lower mortality risk (OR 0·32 vs historic controls) in hospitalized severe COVID-19 pneumonia (esp w/ hyperinflammation, CRP >100 mg/L). Metanalysis of nearly 2000 pts; better resp if given w/ dexamethasone (OR 0·23) https://t.co/7nFAkLgpGK

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Dr. John Cush RheumNow ( View Tweet)

Low dose #methotrexate in primary cardiac prevention #CIRT. Trial had LESS decline in GFR in those with mild renal impairment than placebo. ?meaningful or a fluke. Either way MTX can be used safely in mild CRF! Just follow creatinine/GFR. #ClinicalPearl @RheumNow https://t.co/SyfsxZEeUH

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Janet Pope Janetbirdope ( View Tweet)

“Hiker’s feet” newly proposed cutaneous foot manifestations of dermatomyositis. Most pts had the antisynthetase syndrome (with anti-Jo-1) and almost all had mechanic’s hands. Such findings should prompt a search for ILD https://t.co/98EAQUHJbz https://t.co/mJ467Nfe8T

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Dr. John Cush RheumNow ( View Tweet)
RA patients had a higher 30-day rehospitalization than OA after TKR (OR 1.11) and THR (OR, 1.39). While infections, postoperative complications, cardiac did not differ, RA TKR had less VTE, but RA THR had higher VTE risk (OR, 2.41) https://t.co/QlOWngcEnJ

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Dr. John Cush RheumNow ( View Tweet)

Early Diastolic Dysfunction in Premenopausal Women with RA https://t.co/2pyzT20RCF https://t.co/8viSUbpywX

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Dr. John Cush RheumNow ( View Tweet)
Aortitis: Let’s review the differential for #aortitis including Non-Infectious and Infectious Causes! @febrilepodcast x @RheumOnePagers | created by @MithuRheum @swinndong #IDTwitter #RheumTwitter #FOAMed https://t.co/pR0iTls4PK
Rheum OnePagers RheumOnePagers ( View Tweet)
Claims case-controlled study shows statin use does not increase the risk of #RA - 32,726 RA and matched controls ; statin use (34 vs 32%) slightly increased RA risk (OR 1.12, 1.06–1.18), but signif lost after correcting for hyperlipidemia https://t.co/EcTlyE1MPx

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Dr. John Cush RheumNow ( View Tweet)

"In medical school, they spend days teaching people to operate on lungs, and no time at all helping young doctors learn how to get their patients to stop smoking and get vaccinated." - Seth Godin https://t.co/YIk0O0kDTB

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Dr. John Cush RheumNow ( View Tweet)

Popular read— FDA: New Cardiac and Cancer Warnings for All JAK Inhibitors https://t.co/jayl8ufPHn

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Dr. John Cush RheumNow ( View Tweet)

A retrospective study of systemic sclerosis patients shows that acute hospitalization and mortality were not uncommon and were often linked to SSc-related lung disease. #RheumNow https://t.co/s5wSlndTrt https://t.co/KHz9LYZVAK

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Dr. John Cush RheumNow ( View Tweet)
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