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ARTIC REWIND - Don't Half DMARD Therapy

d Jack Cush, MD

The ARTIC-REWIND study examined rheumatoid arthritis (RA) patients in remission on conventional synthetic disease-modifying antirheumatic drugs (csDMARDs) to see if they could "step-down" their csDMARDs theray; but  the study showed that 25% those who went on half-dose experienced disease fl

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Level, monitor, calculate, glucose, diabetes

Drug Monitoring Ineffective with Infliximab Treatment

d Jack Cush, MD

The predictive value of therapeutic drug monitoring (TDM) while on biologics is debateable; gastroenterology routinely relies on TDM, while rheumatologists do not.

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kid, lupus, pediatric

Childhood Lupus May Hamper Adult Careers

d Jack Cush, MD

Long-term outcomes of kids with childhood-onset systemic lupus erythematosus (cSLE) are uncommon, but this cSLE cohort analysis suggests that SLE significantly impacts their future education, vocation, and employment as they reach adulthood.

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Thyroi, autoimmune

Autoimmune Thyroid Disease in Women

d Jack Cush, MD

JAMA has posted an insights article reviewing autoimmune thyroid disease in women. Thyroid autoimmunity has a higher prevalence in women and with increasing age.



Similar to many autoimmune disorders, thyroid disease is more common in women than in men.

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Results Disappoint for Fecal Transplant in Arthritis

d MedPage Today

Fecal microbiota transplantation (FMT) showed disappointing results among patients with active psoriatic arthritis, a small randomized trial found.

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Systematic review 6 studies of ischemic stroke and Idiopathic inflammatory myopathies (IIM) shows among 5,114 IIM cases there was an increased risk of ischemic stroke (RR = 2.41, 95% CI: 1.31, 4.45), 49% higher in dermatomyositis and Asian IIM. https://t.co/gYdMgmU5Uh

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News Feature: Autoimmune Thyroid Disease in Women JAMA has posted an insights article reviewing autoimmune thyroid disease in women. Thyroid autoimmunity has a higher prevalence in women and with increasing age. https://t.co/P55lMMagyO https://t.co/yMWJClvVJO

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Did you miss last night's Tuesday Night Rheumatology? Watch the playback now. https://t.co/8fjseHpSQV https://t.co/x4NSftQuRQ

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News Feature: Results Disappoint for Fecal Transplant in Arthritis Fecal microbiota transplantation (FMT) showed disappointing results among patients with active psoriatic arthritis, a small randomized trial found. https://t.co/US96DAa9XR https://t.co/IzWZJJe1RX

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May is Lupus month! We've compiled some great lupus resources to share throughout the month. #LupusAwarenessMonth Dr. Janet Pope - Modifying risk of Lupus and RA From ACR 2020 https://t.co/f8a6vHB31e https://t.co/8jteX3F5qg

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Belimumab now approved in the EU for lupus nephritis. The EMA has approved intravenous and subcutaneous Benlysta (belimumab) in combination with background immunosuppressive therapies for adults with active lupus nephritis https://t.co/Twbe1ClT5w

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TNF inhibitor induced (paradoxical) psoriasis in JIA patients was 3 fold higher when TNFi was used - data from 8,222 children in the CARRA registry (54% used TNFi) - rate 8.5 cases/1000PY. https://t.co/HKpAEbtNqr https://t.co/txvmGfpdWf

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27 cases of #immune-mediated diseases post #COVIDVaccination ▶️21 had autoimmune/rheumatic background ▶️17 flares, 10 new onset ▶️Average 4 days post #covidvaccine ▶️>80% had resolution, mostly with corticosteroid 👉🏽https://t.co/zHlFziswU7 via @Vaccines_MDPI @MDPIOpenAccess https://t.co/5ifoBmb9Ux

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Dr Ai Lyn Tan DrAiLynTan ( View Tweet)
#VACOLUP study about #COVID19 #vaccine in #lupus = reassuring data for #SLE patients : side-effects are minor/moderate in 80% and the rate of lupus #flare is stable at 3-4%. Thanks to the 571 patients who have already participated 🙏. Link: https://t.co/I0D52fv4BC https://t.co/us0kQlvkVS

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Laurent ARNAUD Lupusreference ( View Tweet)
Zoomatology – Present in Absentia Unknowingly, you have become a zoomatologist – an old dog who has mastered the new trick. Despite the shutdowns and lockdowns, you can be everywhere, do everything, and learn by being present in absentia. https://t.co/8iAV5gvkkt https://t.co/zEYvnVuari

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New download available! Osteoarthritis vs. Rheumatoid Arthritis https://t.co/qvVEcKqNAM https://t.co/3f8sRSgyQo

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News Feature: Higher Cardiovascular Risks with Systemic Lupus Erythematosus The Journal of the American College of Cardiology has published a study showing that patients with SLE have an increased risk of HF and other long-term cardiovascular outcomes. https://t.co/g07tIP5jBx https://t.co/3fHzgrJjUi

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News Feature: Uric Acid: A Major Player in the Metabolic Syndrome Uric acid, and hyperuricemia, has been closely linked with may of the components of the metabolic syndrome, which is largely a consequence of excessive fat storage. https://t.co/ObQ0LURodb https://t.co/HT35ODnFkn

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Risk factors for Kawasaki disease in Taiwan compared 4197 KD pts to controls. KD was more common in Males (OR 1.47), older mothers (>35 y; OR, 1.18), and in multivariable analysis, maternal ankylosing spondylitis (OR 2.02). https://t.co/4qbddaYkqY

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Real world comparision of baricitinib (n 138) and tofacitinib (n 156) in #RA patients shows at wk 24, BARI out performed TOFA - CDAI remission (40.4 vs 28.3%) and CDAI LDA (81.6 vs 69.3%); safety signals were equal between groups. https://t.co/0quNNGB18K

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