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Muscle Loss and Frailty in Rheumatic Disease

d Paul Sufka, MD

At the 2019 ACR annual meeting, several abstracts looked at the importance of myopia (muscle wasting due to illness at any age) and sarcopenia (age related muscle wasting) in the setting of various rheumatologic diseases.

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ACR 2019 - Report From Day 2 (Monday)

d Jack Cush, MD

Monday was another full day of sessions and studies here in Atlanta. Following is my roundup of day two.

The Safety of Methotrexate

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Influenza Vaccine Updates And Pearls At ACR 2019

d Cassandra Calabrese, DO

As we enter flu season it is of the utmost importance that we remember to assess our patients’ influenza vaccine status at each visit.

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PANLAR Ultrasound Study Group: Recommendations On Imaging Modalities In Gout

d Olga Petryna, MD

Gout is a systemic inflammatory disease with high potential for joint damage due to erosive changes and MSU deposits resulting in disability and chronic pain. Prompt diagnosis and effective treatment are key to better long term outcomes and decreased disability.

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ACR 2019 – Best of the Plenary Sessions

d Jack Cush, MD

The ACR Plenary Sessions featured some of the best research presented on Sunday, Monday, and Tuesday in Atlanta. Here are my seven notable highlights from the Plenaries.

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Hepatitis C-Related Cryoglobulinemic Vasculitis

d David Liew, FRACP

Flares of vasculitis can still be a problem after hepatitis C-related cryoglobulinemic vasculitis patients are cured of their hepatitis C by direct-acting antivirals, as demonstrated by data from four registries presented at ACR 2019 in Atlanta, Georgia.

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ACR 2019 - Report from Day One (Sunday)

d Jack Cush, MD

Sunday was the first full day of scientific sessions at the 2019 ACR/ARP meeting in Atlanta. Yesterday we shared our initial news articles, videos and more with you. Following is my roundup of day one. 



Delays in Diagnosis

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MRI in the Diagnosis and Management of Polymyalgia Rheumatica

d Paul Sufka, MD

Polymyalgia rheumatica (PMR) is a common condition seen by both primary care and in the rheumatology office.

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Can the Happiest Subspecialists Experience Burnout?

d Kanika Monga, MD

The Medscape’s Physician Lifestyle & Happiness Report 2019 crowned rheumatologists as the happiest subspecialists. We topped the list with 65% of the respondents indicating that they were happy outside of work.

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Autoinflammatory Diseases at the ACR Annual Meeting

d Jonathan S. Hausmann, MD

It has been a wonderful year for autoinflammatory diseases at the ACR Annual Meeting.

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Long term results for GCA pts on TCZ (GiACTA): No new safety signals. Nearly 50% of those on TCZ QW maintained remission. Flares noted in PBO/ cessation TCZ and remission restored in majority once TCZ restarted. https://t.co/DN6TWYgWsH Plenary abs #808 #ACR19 @uptoTate

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Dr. John Cush RheumNow ( View Tweet)

99mTc-maraciclatide (which binds integrins) whole body imaging has similar uptake to PDUS evaluation for synovial inflammation. It is quick, and widely available. Cost may be prohibitive, however. Abstract #286 https://t.co/4LqrzcoA9U #ACR19 @uptoTate

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Dr. John Cush RheumNow ( View Tweet)

ACR has released 3 FREE "SPOTLIGHT" Slide Decks on RA, SLE, SpA; ~15 slides each deck; compilations of cool abstracts presented at #ACR19. Use the link supplied below https://t.co/CsKVMDoGoL

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Dr. John Cush RheumNow ( View Tweet)

FINCH3: FILGOTINIB studied in this cohort naive to MTX; interesting that safety data looks good! Maybe too early to tell. Abst# 927 https://t.co/AonswiGYG3 https://t.co/q3OU582WbT

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Dr. John Cush RheumNow ( View Tweet)
abstr#0848 - Retrospective study Medicare database to evaluat outcomes of chronic low dose steroids (GCs) in Rheum Dz: n= 246,297, 47% on GCs. Pts on steroids have : 1. ⬆️ use of narcotics (pain) 2. RA 3. ⬆️hosp visits related to infx 4. Less f/u https://t.co/xD8isyKZsz

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Dr. John Cush RheumNow ( View Tweet)

Plenary session shows AA/blacks at higher risk for #SLE & that blacks have 16 fold increased risk for IHD, CVD. CV risk accelerated at yrs 1 & 10. Copy & paste. #ACR19 Abst 805 https://t.co/pW8JdGxCUf https://t.co/lLPTnyTa2z

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Dr. John Cush RheumNow ( View Tweet)
Abstr#1898 #acr19 @kDAO2011. Danish prospective RA registry of pregnancy & offspring n= 816 - kids of moms w/ RA performed a little worse in math grades 2,4,6, 8 compared to peers regardless of maternal seropositivity. No influence by paternal RA. https://t.co/bOBDtjVtfm

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Dr. John Cush RheumNow ( View Tweet)

Klemperer Lecture Dr J James: 25% people have +ANA, but only 5-8% dev an autoimm dz. Why do most ANA+ pts not develope dz, Note that “healthy” ANA+have both inflamm and suppressive CK profiles compared to ANA neg and SLE pts @KDao2011

Dr. John Cush RheumNow ( View Tweet)

Up to 20% of Sjogrens patients may not have sicca symptoms, especially those with CNS dz. Dr. F. Vivino #ACR19

Dr. John Cush RheumNow ( View Tweet)

Abstract L06 shows the efficacy of Emapalumab, an IFN-γ mAb, when given to 9 systemic JIA pts who developed macrophage activation syndrome. Highly effective showing ability to lower steroid use #ACR19 https://t.co/hduMrzWt72

Links:

Dr. John Cush RheumNow ( View Tweet)

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