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Mortality and Hospitalization with Pulmonary Hypertension in Systemic Sclerosis
PHAROS is a prospective cohort studying the natural history of pulmonary hypertension (PH) in systemic sclerosis (SSc). They have shown that risk factors for poor outcomes in this cohort included male sex, DLCO < 50%, exercise oxygen desaturation, and pericardial effusions.
Read ArticleRheumNow Podcast – Downside of Lupus (2.9.19)
Dr. Jack Cush reviews this past week's news and reports from RheumNow.com:
Read ArticleEarly Predictive Factors for Scleroderma Renal Crisis
It has been historically said that risk factors for scleroderma renal crisis (SRC) includes include cold exposure, steroid use, dehydration, rapid progression of skin disease, tendon friction rubs, anti-RNA polymerase III antibodies and pregnancy. A new study examines risk factor for S
Read ArticleCV Risks Similar in Systemic Sclerosis and Rheumatoid Arthritis
Interactions between disease-related inflammatory processes and the development of several morbidities have been well-studied in RA, particularly heart disease. This is not the case for the often-lethal SSc (estimated standardized mortality ratio between 2.5 and 4.0).
Read ArticleScleroderma Expert Treatment Preferences
Frustration may be the word that best characterizes many scleroderma management plans - owing to a lack of trials, lack of agreement and lack of clear guidance on management.
Read ArticleRheumNow ACR Week in Review: ACR Wrap-Up (10.26.18)
This past week in Chicago gave us a plethora of new and eye-opening research, people, KOLs, exhibits, sessions, guidelines, posters and a never-ending supply of coffee served in small paper cups. ACR 2018 highlights for me included:
Read ArticleACR 2018 Podcast - Day 3
Audio Highlights and Interviews from Day 3 at the ACR 2018 meeting LISTEN HERE
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ACR 2018 - Day 1 Report
RheumNow is in Chicago covering the ACR annual meeting. Here are the highlights from Sunday (day one). Be sure to check our complete coverage, including articles, video reports and tweets, at acr18.rheumnow.com.
Read ArticleSLE-Scleroderma Overlap Outcomes
Overlap of autoimmune disorders represents a significant diagnostic and management challenge to the rheumatologist. A novel cohort analysis of overlap between systemic sclerosis (SSc) and systemic lupus erythematous (SLE) suggests such patients tend to be younger, more frequently have PAH, but less cutaneous manifestations of SSc.
Read ArticleBreast Implant Study: More Worries or Not?
The Annals of Surgery reports on an anlaysis of FDA-mandated postmarket studies, including nearly 100,000 breast implant pprocedures, that showed silicone implants to be associated with higher rates of Sjögren's syndrome, scleroderma, rheumatoid arthritis, stillbirth, and melanoma.
Read ArticleOutcomes of Systemic Sclerosis Hospitalization
A study of inpatient systemic sclerosis (SSc) hospitalizations using the 2012–13 National Inpatient Sample database finds an inpatient mortality rate of 5%, and that infection was the most common cause of SSc hospitalizations and in-hospital death.
Read ArticleThe RheumNow Week in Review – Cocoon Therapy? (7.20.18)
Dr. Jack Cush reviews highlights from the news and social media on RheumNow.com in the past week.
Read ArticleSystemic Sclerosis: More Common than Expected
Systemic sclerosis is more common in the United Kingdom than previously reported, a nationwide population-based study determined.
Read ArticleThe RheumNow Week in Review – Baricitinib Splash (6.7.18)
Dr. Jack Cush discusses the past week's news and journal articles featured on RheumNow.com - including reports on advance practice clinicians, baricitinib, gout, disease activity, hypomagnesemia and upadacitinib.
Read ArticleSPAR Predicts ILD Progression in Systemic Sclerosis
The development and progression of interstitial lung disease in systemic sclerosis can be an ominous finding.
Read ArticleThe RheumNow Week in Review – Why Comorbidity is Like the Weather (5.3.18)
Dr. Jack Cush discusses the news and journal articles from the past week on RheumNow.com.
Read ArticleThe RheumNow Week in Review – Vitamin D Snark Report (4.20.18)
Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com. A second life for Syk kinase, Vitamin D talk, VTE, regulatory hearings and the Lupus clinic edge.
Read ArticleThe Consequences and Cure of Hepatitis C
I spent this past week seeing hepatitis C patients with our hepatologists, and being a rheumatologist, I was looking forward to seeing extra-hepatic manifestations of HCV that we read about in text-books - cryoglobulinemic vasculitis, sicca syndrome, porphyria cutanea tarda and many others. I suppose I should not be surprised that the week passed without seeing a single one of these.
Read ArticleAbatacept Improves GvHD Outcomes
The results from a phase 2 clinical trial presented at the American Society of Hematology meeting demonstrated that the drug abatacept was highly effective in managing severe acute graft-versus-host disease (GvHD) in patients receiving hematopoietic stem cell transplants.
Read ArticleThe RWCS - RheumNow Week in Review - 9 February 2018
Dr. Jack Cush reviews highlights, news and recent research published this week on RheumNow.com. This week's report includes news and education from the RWCS meeting in Maui.
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