Off-label use of prescription drugs was associated with adverse drug events in a study of patients in Canada, according to an article published online by JAMA Internal Medicine.
Using Medicare claims data, a retrospective cohort study analyzed the risk of a second non-melanomatous skin cancer (NMSC) in 9460 individuals (6841 with RA and 2788 with IBD).
The overall incidence rate of a second NMSC was roughly the same for RA and IBD patients, 58.2 per 1000 person-years and 58.9/1000PY in IBD, respectively.
Each month, RheumNow reviews compiled listings of drug shortages germane to the practive of rheumatology using several sources. If you have suggestions or information about specific drug shortages or drug safety issues please email us at info@rheumnow.com.
Our primary sources of information include: Drugs.com, the FDA and the University of Utah pharmacy (see table below).
A Danish cohort study examined patients with hyperuricemia and compared outcomes in those proven to have urate crystal deposition (317 patients) and matched 1:1 to patients without urate crystals. Interestingly, of the 80,726, 79,629 did not have uric acid crystal identification.
MONTREAL -- An immunosuppressive drug was as effective as a standard agent for interstitial lung disease (ILD) associated with scleroderma, a researcher said.
But mycophenolate (CellCept)was better tolerated than the old standby, the oral alkylating agent cyclophosphamide, according to Donald Tashkin, MD, of the David Geffen School of Medicine at the University of California Los Angeles.
A team of Japanese investigators examine 126 patients with ANCA-associated renal vasculitis to see if ANCA levels would predict disease relapse.
Using death certificate data from US National Vital Statistics System of the National Center for Health Statistics (NCHS) and the Centers for Disease Control and Prevention, JAMA reports a downward trend in death rates in the USA from 1969 - 2013).
Are you efficient, productive and accurate in what you do? Could you be better? Or do the job differently?
The October 27 issue of JAMA reports a study of federal marketplace insurance plans shows roughly 15 percent completely lacked in-network physicians for at least one specialty, a practice found among multiple states and issuers.
Rheumatology News reports the results of a novel trial presented at the European Academy of Dermatology and Venereology meeting in Copenhagen.
I have a 21 yr. old lupus nephritis patient on mycophenolate, hydroxychloroquine and prednisone 40 mg per day. She says both her current nephrologist and her prior pediatric rheumatologist told her NOT to get pneumococcal and flu vaccines. I thought she is supposed to get them - any comment?
Despite concerns over safety, the FDA Arthritis Advisory Committee voted favorably to approve lesinurad (LES) at a meeting held Friday, October 23, 2015. Overall, panel members felt the potential benefits of LES outweighed the safety concerns reviewed by the FDA presenters.
Vertebral fractures are not uncommon in patients with ankylosing spondylitis and spondyloarthritis. However, they may be difficult to diagnose as they may not present with typical features of an acute fracture, may be overlooked as a disease flare of spondylitis or may only be incidentally found on unrelated imaging studies.
A comparison of mycophenolate mofetil (MMF) and low-dose cyclophosphamide IV (CYC) in the treatment of lupus nephritis (LN) was examined in 173 patients with class III, IV, or V LN.
A recent analysis of randomized clincal trials (RCT) for the treatment of neuropathic pain has shown in increase in placebo responses. (Citation source http://buff.ly/1LL8yAi)
