Sjogrens

RheumNow Podcast – I Wanna New Drug.V2 (9.24.2021)

Save

Almost three years ago to the day, I did a podcast entitled, "I wanna new drug." As I go over this week's podcast, I want to say it again. I want a new drug safe enough to use during pregnancy, for PMR, for GVHD, and more. I'm going to cover these, and other topics including lupus, COVID

CRESS – A New Composite Measure for Primary Sjögren's Syndrome

Save

Randomized clinical trials in primary Sjögren's syndrome (pSS) are fraught with fault and inconclusive outcome measures, including the more recently developed EULAR Sjögren's Syndrome Disease Activity Index (ESSDAI).  There's a new composite endpoint outcome for RCTs in pSS, called the Composite

Potential Birth Defects with Hydroxychloroquine

Save

Hydroxychloroquine (HCQ) is one of the safest meds used in rheumatology, but there is new claims data suggesting a small increase in the risk of malformations associated with first-trimester HCQ use.

While HCQ is generally considered safe in pregnancy, studies have been too few and

Do B-cell targeted therapies still have a place for the treatment of Sjogren’s?

Save

B-cells play a major role in the pathogenesis of primary Sjogren’s syndrome (pSS) through antibody-dependent and antibody-independent functions, as well as evident by progression to B-cell malignancies/lymphoma. Hence, targeting B-cell is attractive. Despite efficacy of B-cell depleting therapy

Can the Focus Score predict Lymphoma in Sjogren’s syndrome?

Save

Patients with Sjogren’s syndrome are nearly 19 times more likely to develop lymphoma, so identifying factors that impact this risk development is a major goal in caring for this disorder. Many risk factors are established such as low C4, palpable purpura, parotid gland enlargement, and

Sinusitis Activity Linked to Brain Dysfunction

Save

Have you wondered why fibromyalgia, fatigue or cognitive dysfunction often co-associate with chronic sinusitis?

A case-control study of 22 patients with chronic rhinosinusitis published in JAMA Otolaryngology–Head and Neck Surgery found that sinonasal inflammation was

Answering questions on how COVID-19 affects rheumatic patients

Save

As we inch closer to a possible vaccine for COVID-19, we are finally filling in the details on how the pandemic is affecting every aspect of our patient’s lives.