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How Often Do You Monitor MTX? (6.16.2023)

d Jack Cush, MD

Dr. Jack Cush reviews the news and journal reports from this past week on RheumNow.com, including new drug approval, a new SpA variant and new rules for methotrexate (MTX) monitoring and depression screening. 

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ACR Concerned with MedPAC’s Cutting Part B Reimbursement

d ACR

The American College of Rheumatology (ACR) today expressed disappointment that the Medicare Payment Advisory Commission (MedPAC) has recommended yet another cut to physician reimbursement for infusing life-altering treatments as part of its June 2023 Report to the Congress: Medicare and the Healt

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Higher Genetic Loads Linked to Worse Systemic Lupus

d Jack Cush, MD

A Korean study of a large systemic lupus erythematosus (SLE) cohort shows by genomic analysis, that higher weighted genetic risk scores (wGRS) is associated with earlier SLE onset, higher anti–Sm antibody positivity, lupus nephritis and more diverse lupus manifestations.

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Should we be reassured of JAK safety with new data? Dr. Janet Pope discusses abstracts OP0133 and OP0132 at EULAR 2023 in Milan, Italy. https://t.co/gxLJGHXwlm https://t.co/SgdGRJXBIi

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Bimekizumab (Bimzelx) has been EMA approved to treat adults with active PsA & axial spondylarthritis in the EU. This dual IL-17 A/F inhibitor is approved to treat moderate -severe plaque psoriasis in the EU, Canada, UK & Japan; but not yet in USA https://t.co/DGczkgHtpZ https://t.co/TquFCuh4QG

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Swedish registry study shows of 3629 children born to mothers with RA#, 70 (1.94%) were diagnosed with Autism Spectrum disorder (ASD). If RA was dx before delivery, an increased risk of ASD (HR = 1.43), especially for seronegative RA (HR = 1.61) https://t.co/fA6gzta5rx https://t.co/mGdzTqjEr7

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RheumNow’s newly launched Poster Hall features sponsor-generated clinical trial posters designed to educate and inform. Check out our Poster Hall today! https://t.co/opulSMICUf https://t.co/XtWePsWQCt

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Assessment of Psoriatic Arthritis: A Global Perspective Drs. Antoni Chan, Nelly Ziade and Ihsane Hmamouchi discuss POS1542 presented at EULAR 2023 in Milan, Italy. https://t.co/qkhdNDn37k https://t.co/Ux4PCxRdn8

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Dazodalibep: A Glimmer of Hope is Sjogren's Syndrome? Dr. Yuz Yusof reports on abstracts OP0143 and LB0003 presented at EULAR 2023 in Milan, Italy. https://t.co/TPcdJ2rIsP https://t.co/5WZizA0TU8

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What to do with all this JAKi safety real world data? Dr. David Liew reporting from EULAR 2023 in Milan, Italy. https://t.co/AgDBOxAUx6 https://t.co/iRZuT0g7vq

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Why Depression Screening Should be Mandatory at Each Visit Depression is more widespread than ever in the US, according to a new study from Gallup, showing that 18% of adults are depressed– an increase in 7 percentage points since 2015. https://t.co/2u82MXIFvb https://t.co/ZpGi4TYdBL

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High Mortality Rates with Depression in Rheumatoid Arthritis A Danish cohort study has shown a deadly association between depression and rheumatoid arthritis (RA). https://t.co/R2MB4bs0Hr https://t.co/rWIfHmBqr8

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Excessive alcohol intake associated with higher risks of 61 diseases in men, including liver cirrhosis, stroke, and several gastrointestinal cancers, gout, cataracts, some fractures, and gastric ulcer. https://t.co/WqMuHQ3Unn https://t.co/IU0SaRcswZ

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519 pts in the Hand OSTeoArthritis in Secondary care (HOSTAS) cohort studied & 17% had prolonged morning stiffness (>60 min); mild in 30%, intermediate in 37%, severe in 18% and extreme in 4%. Assoc w/ more pain, worse function and QOL https://t.co/6LSir7nSae https://t.co/lhoxwpfuqD

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Study of 162axSpA pts found that 46.6% reported abnormal sleep behavior, worse in Female patients vs males (P <.001). Such pts were more likely to have depression (P = .015) and worse health-related QoL (HRQOL) (P = .015) https://t.co/a1OoUTPKiV https://t.co/gkjkkdljOh

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Study of 2883 pediatric patients with Hidradenitis Supprativa (HS), finds a higher risk of Crohns disease - 0.69% of HS and 0.17% of control patients developed CD (OR 4.90, 3.07-7.84; P < .001) higher in patients with HS than in control patients. https://t.co/gcfT4CET5h https://t.co/vQIzIzwsmn

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We should put the CART before the T in SLE! Dr. Janet Pope ( @Janetbirdope ) reports from EULAR 2023 in Milan, Italy. https://t.co/HwYphsg3ad https://t.co/Ghu2M6yaFn

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Still's Disease Abstracts at EULAR 2023 https://t.co/1gNf8RUDLi https://t.co/1f1ERUOS03

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WATCH: Update on CAR T-Cell Therapy in SLE & Autoimmune Diseases Dr. Peter Nash reporting from EULAR 2023 in Milan, Italy. https://t.co/r5cMWYHk9A https://t.co/8Si1kUmzAs

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EULAR 2023 Day 4 Recap Join Drs. Jack Cush, David Liew and Bella Mehta as they recap data presented on Day 4 at EULAR 2023 in Milan, Italy. https://t.co/3VP1dB6YHp https://t.co/mSBB3bDWRl

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