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Lupus Linked With Greater Risk of Cardiovascular Complications of Childbirth
Pregnant women with systemic lupus erythematosus (SLE) were more prone to cardiovascular complications during delivery, and their risk seems to have increased over the past 15 years, according to national administrative data.
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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.
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Rheum Manpower Needs - More Programs
https://t.co/W0mOCkyJbI https://t.co/USXTAtrE6U
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The spicy topic of turmeric in RA
Curcumin has increasingly been promoted as a potential RA therapy, but data presented at #ACR22 suggests it is unable to do any better than placebo in replacing conventional rheumatoid arthritis therapies.
https://t.co/C0O0DyXn34 https://t.co/kv3dw476dT
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Dual target blockade may be better than one in SLE
Inhibition of B-cell Activating Factor (BAFF) has revolutionised the treatment of patients with systemic lupus erythematosus (SLE).
https://t.co/uu6ygb4l8B https://t.co/nLO3oSiEVa
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JAK inhibitors in rheumatic diseases
Dr. Antoni Chan ( @synovialjoints) discusses abstracts 0510 and 0404 at #ACR22
https://t.co/7SSJITLrRT https://t.co/utjf8vlJof
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AI Future of Sacroiliitis Assessment
Dr. Rachel Tate ( @uptoTate) speaks with Dr. Fabian Proft about Abstract 0383 at #ACR22 Convergence.
https://t.co/pfeW4iQBLq https://t.co/0lFx6CpWCx
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Can I stop Methotrexate in RA?
Dr. Pope and Dr. Meng discuss Abstract 0916 at #ACR22.
https://t.co/0hK5kNHlrS https://t.co/AXJija7Yzo
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Remibrutinib in Sjogren's Syndrome
Dr. Putman reports on abstract 1113 presented at #ACR22 Convergence Abstract 1113: Remibrutinib (LOU064) in Sjögren’s Syndrome: Safety and Efficacy Results from a 24‑Week Placebo-controlled Proof-of-Concept Study
https://t.co/ymFkNWPaXo https://t.co/0k6vLIu0Ku
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Rheum Drugs & IDSA Guidelines to Treat COVID-19
https://t.co/39wTAKW83E https://t.co/ir1x66FSQ8
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RECITAL Trial: RTX vs. CTX in CTD-ILD
A UK study suggests the equivalent outcomes when patients with ILD associated with CTD are treated with either intravenous RTX or CTX, but with fewer adverse events with RTX.
https://t.co/5yaPDaw8pZ https://t.co/kcKLkIv1bK
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Recent CDC/MMWR report shows Paxlovid x 5days (including those w/ prior COVID or vaccination), had a 51% lower hospitalization rate within 30 days after diagnosis than those not prescribed Paxlovid. Use it irrespective of vaccination status https://t.co/CBc1VBSDFR https://t.co/EC8QGaFrb3
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Future therapy? Nanoparticles laced with rapamycin to nanoparticle stimulate regulatory T cells to suppress autoimmune disease (tested in a mouse model). https://t.co/JHFh82siff https://t.co/Y8itPXiPho
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Impressive free read and review of Neutrophils and Netosis in Autoimmune and Autoinflammatory disorders (Nature Reviews) from Kapland & Wigerblad at the NIH. https://t.co/w4cIwcQMkt https://t.co/ReA9xM2X4j
Dr. John Cush RheumNow ( View Tweet)
Topic Podcasts - Lupus Part2
#ACR22 Daily Recap: Saturday Recap New Treatments for SLE?
https://t.co/uRI3Q3eI6E https://t.co/wBXfXw7z8J
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Just Can’t Get Enough of Hydroxychloroquine
Several studies on HCQ dosing were presented in the poster and abstract sessions. HCQ has numerous benefits backed by evidence and unless absolutely contraindicated, patients should be maintained on it. Yet...
https://t.co/n8drUDDDjh https://t.co/AIoV3s2VhJ
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Steroid injections worsen knee arthritis
Two studies comparing injections commonly used to relieve the pain of knee osteoarthritis found that corticosteroid injections were associated with the progression of the disease.
https://t.co/v7cDBKfM9c https://t.co/sbJ1ro0orW
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Low Dose IL-2 Therapy in Sjögren’s
There is a large, unmet need in treating Sjögren’s syndrome, yet a new randomized clinical trial has shown that lLD-IL-2 was effective and well tolerated in patients with pSS, with evidence of restored immune balance.
https://t.co/0obaV0wnGX https://t.co/vgy91cYYvp
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Topic Podcasts - Lupus Part1
-A Novel Treatment Response Measurement Tool for Lupus
-Breakthrough COVID infection in SLE during Omicron era
Effect of voclosporin in class V lupus nephritis
and more.
https://t.co/RVhpZtoo6b https://t.co/jjOZbLZN9m
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Pre-RA Pharmacological Interventions: Delaying is not Enough
Dr. Aurelie Najm reports on both the Great Debate as well as abstracts 0530, 1603 at #ACR22
https://t.co/n8hzJMpmWO https://t.co/8OISSK34No
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Dr. John Cush RheumNow ( View Tweet)