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Febuxostat Safe in Gout with Moderate-Severe Renal Impairment
Renal impairment is a risk factor for gout and a barrier to optimal gout management. Many of the drugs used to treat gout require adjustment in those with renal disease.
Read ArticleRWCS 2016 – OA/OP, Gout, Sarcoid & JIA Reviewed
Recent Developments in Osteoarthritis, Osteoporosis and Gout
Read ArticleLesinurad augments uric acid lowering effect in allopurinol non-responders
As the never-ending battle with refractory gout continues, the need for more safe and effective treatments remains. Often, steady remission and target urate levels are not achieved with allopurinol alone.
Read ArticleCan Gout and Rheumatoid Arthritis Coexist?
German investigators studied 100 RA patients with a uric acid > 6 mg/dl and assessed them for MSU crystal deposit with dual energy computed tomography (DECT) of both feet and hands.
Read ArticleRA Guidelines, Methotrexate and Mortal Risks in Gout: November 2015 top social media news
Here's what you may have missed: in November 2015, RheumNow published 80 tweets on news, research and teaching points that impact the rheumatology community. We had a reach (impressions) of 79,100, 79 mentions, and over 3399 visits to RheumNow.com to check out what we publish.
Read ArticleReduced Uric Acid from Weight Loss Tied to Triglycerides
Weight loss is one of several nonpharmaceutical interventions to reduce serum urate (SUA) levels and control gout. French researchers examined the role of xanthine oxidase (XO), low-grade inflammation, and weight loss on SUA levels in obese patients.
Read ArticlePrudent Diet Reduces Risk of RA and Gout
The 2015 ACR meeting in San Francisco highlighted several studies wherein dietary patterns predicted a reduced risk of both rheumatoid arthritis (RA) and gout.
Read ArticleIncreasing Trends for Prescription Drugs, But Not for Arthritis Drugs
JAMA reports the results of trends in drug use in the USA over a 13 year period using data derived 37959 adults survey in the National Health and Nutrition Examination Survey (NHANES).
Read ArticleNo Correlation Between Urate Crystal Identification and Cardiovascular Risk
A Danish cohort study examined patients with hyperuricemia and compared outcomes in those proven to have urate crystal deposition (317 patients) and matched 1:1 to patients without urate crystals.
Read ArticleFDA Panel Votes 10-4 to Approve Lesinurad for the Treatment of Hyperuricemia/Gout
Despite concerns over safety, the FDA Arthritis Advisory Committee voted favorably to approve lesinurad (LES) at a meeting held Friday, October 23, 2015. Overall, panel members felt the potential benefits of LES outweighed the safety concerns reviewed by the FDA presenters.
Read ArticleFDA Reviews the Safety of Lesinurad in Gout
Lesinurad is a novel URAT-1 inhibitor being developed as a urate-lowering therapy for gout by Astra-Zeneca.
Read ArticleSleep Apnea Increases Risk of Gout
Zhang and colleagues from Boston analyzed patients with physician diagnosed sleep apnea from The Health Improvement Network in the UK and compared these with 5 controls (age, sex, BMI matched). They studied 9,865 patients with sleep apnea and 43,598 controls.
Read ArticleInitiation of Urate-Lowering Therapy During Gout Attacks
A retrospective analysis examined whether it's better to initiate urate-lowering therapy (ULT) during or after an attack of acute gout.
Read ArticleVisceral and Liver Fat Linked With Men's High Urate
Both visceral and liver fat accumulation significantly increased the risk of hyperuricemia in men, a cross-sectional Japanese study found.
Read ArticleHealth Hazards of Fructose and Soda
The health consequences of fructose-containing sugars, sucrose and high fructose corn syrup, found in sugar-sweetened beverages and foods, may be numerous and include obesity, type 2 diabetes, gout and cardiovascular disease.
Read ArticleGout: New Classification Criteria from ACR/EULAR
The American College of Rheumatology and the European League against Rheumatism joined forces to finalize classification criteria for gout, a condition that affects 8.3 million Americans.
Read ArticleHyperuricemia, Death & Kidney Disease
In a recent study published in the Journal of the American Geriatrics SocietyTaiwan investigators examined the Annual Geriatric Health Examination Program database (2006 to 2010) to estimate the all-cause, cardiovascular, and cancer mortality risks associated with serum uric acid le
Read ArticleRheumatologists are Not Always Aligned with 2012 ACR Gout Guidelines
A cross-sectional survey of 309 Brazilan rheumatologists was performed to assess their compliance with the 2012 ACR guidelines on gout.
Read ArticlePsoriasis and Psoriatic Arthritis Have an Increased Risk of Gout
The frequency of gout among patients with psoriatic disease was studied in two cohorts of 98,810 patients from the Health Professionals Follow-up Study (1986-2010) and the Nurses' Health Study (1998-2010).
Read ArticleAllopurinol Risky in Asian Population
The go-to drug to treat hyperuricemia and gout, allopurinol, put patients at risk for developing hypersensitivity when American College of Rheumatology guidelines weren't followed, a large database study found.
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