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RheumNow Week in Review – 4 November 2016
Dr. Jack Cush reviews highlights and reports from this week on RheumNow.com, including drug-induced cutaneous lupus, pediatric lupus being worse, new gout drug SEL-12, Gut microbiome and IgA plasmablasts, and the weakly-received new ACP guidelines on gout.
Read ArticleHigher Lupus Disease Activity in First Year Postpartum
Most women with systemic lupus erythematosus (SLE) have no or little disease activity during pregnancy, but experience greater disease activity or overt flares during the first year postpartum, a Norwegian study has found.
Read ArticleGood News for Lupus Pregnancies
The Washington Post recently interviewed Dr. Eliza Chakavarty of the OMRF about the evolution in attitudes and outcomes of lupus women who wish to get pregnant.
Read ArticleLow-Molecular Weight Heparin Does Not Reduce Pregnancy Complications
A Lancet meta-analysis has reviewed the preventative effects of low-molecular-weight heparin (LMWH) on placenta-mediated pregnancy complications include pre-eclampsia, late pregnancy loss, placental abruption, and birth of a small-for-gestational-age (SGA) neonate.
Read ArticleRheumNow Week in Review – 19 August 2016
Dr. Cush reviews the RheumNow.com highlights in rheumatology for the week ending 19 August 2016.
Read ArticleEULAR: Guidance for Managing Lupus Pregnancy
The European League Against Rheumatism (EULAR) has published comprehensive recommendations on reproductive health and family planning for women with systemic lupus erythematosus and/or antiphospholipid syndrome – conditions that largely affect women of childbearing age.
Read ArticlePravastatin Improves Obstetric Outcomes in Anti-Phospholipid Syndrome Patients
Pregnancy complications of anti-phospholipid syndrome (APS) have included recurrent abortions, spontaneous fetal loss, preeclampsia, and premature birth. The etiopathogenesis of these events has been presumed to be placental thrombosis or infarction.
Read ArticleAngiogenic Biomarkers Predict Adverse Outcomes Pregnancies in Lupus
The PROMISSE (Predictors of Pregnancy Outcome: Biomarkers in Antiphospholipid Antibody Syndrome and Systemic Lupus Erythematosus) study has revealed several important lessons in lupus care.
Read ArticleRheumNow Week in Review – 1 July 2016
Dr. Jack Cush reviews highlights from the news and social media in the past week on RheumNow.com
Tocilizumab in Pregnancy
Tocilizumab is currently listed as a Category "C" pregnancy risk based on limited pre-clinical (animal) data that was negative.
Read ArticlePregnancy Complications in Primary Sjogren's
Sjogren's syndrome is a highly prevalent disorder, affecting women ten times more frequently than men. Although the typical onset follows menopause, a minority of women may develop primary Sjogren’s syndrome (pSS) during child-bearing years.
Read ArticleApril-May 2016 Top Social Media News
In April and May 2016, RheumNow sent 82 tweets regarding news, research and teaching points that strongly impacted the rheumatology community and resulted in a reach of 203,500 impressions, with 136 mentions, and over 6378 visits to RheumNow.com. Here are the top tweets from April and May.
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Biologics Are Safe When Used During Pregnancy in IBD
This is a reposting of an earlier report on RheumNow that includes additional commentary from Dr. Sunada Kane, a gastroenterologist at the Mayo Clinic who specializes in both inflammatory bowel disease (IBD) and pregnancy.
Read ArticleMMWR Update on Zika Virus: 116 US Cases Related to Travel
The Centers for Disease Control and Prevention (CDC) reported that in the last year (January 2015 to February 2016), they have identified and confirmed 116 cases of the Zika virus among US residents, with nearly all having traveled to endemic regions.
Read ArticlePregnancies are Adversely Affected Even Before the Diagnosis of Lupus
Arkema and colleagues assessed maternal and fetal outcomes in patients with SLE, pre-clinical (prior to onset) SLE and prevalent maternal SLE during pregnancy compared with the general population.
Read ArticleRWCS 2016 – Periodic Fever and Macrophage Activation Syndrome + Pregnancy in IBD
Pregnancy and Immune Modulating Therapies
Read ArticleIncreased Congenital Anomalies in Children from Women with a Juvenile Arthritis History
A Quebec administrative claims analysis examined the birth outcomes of women with a history of juvenile idiopathic arthritis (JIA) who subsequently had a first-time birth (between 1983-2010).
Read ArticleNo Significant Increased Risk with TNF Inhibitors During Pregnancy
A population-based study of 1,272,424 live-born infants from Denmark and Sweden examined the prevalence of birth defects among infants born to 683 women with chronic inflammatory disease (inflammatory bowel disease, rheumatoid arthritis, ankylosing spondylitis, psoriatic arthritis, or psoriasis)
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