RheumNow Week in Review – How Not to Treat Hand OA (8.24.18) Save

Dr. Jack Cush comments on the last week's news and journal highlights on RheumNow.com.

1. Comparative study of pregnant women with RA (n=657), JIA (170) vs 564 controls shows RA and JIA have 2 fold higher rates of pre-term delivery and risk of PTD was highest with disease activity and corticosteroid use. https://t.co/FPmtPbtxUM
2. Subanalysis of 221 pts in MeTeOR study shows persistent and extensive effusion‐synovitis Knee Osteoarthritis (with meniscal tears) is associated with greater degrees of cartilage loss over 18 mos. https://t.co/3KtHQx0QI2
3. PLEASE- stop trying Plaquenil, DMARDs, biologics in Hand OA - they dont work!!. My best regimen is: simple analgesics (acetaminophen 1950 mg qd) plus 2.5 mg prednisone, hand OT, and painful PIP/DIP immobilization with 2inch Cohesive tape x 14days https://t.co/VOzs0yWjOS
4. A multinational study of 1,545 SLE patients followed for a mean of 7+ years shows those with proteinuria incur 4 fold higher costs ($20k -->84K) & those with GFR < 30cc incur 15 fold higher costs. ($20k-->310K) https://t.co/fS7rSnn2mE
5. Romanian Tuberculosis  Study of 550 RA, PsA, AS patients on TNF inhibitors (where population risk is 97 per100k PY); found incidence of TB on TNFi to be 1348.0, 862.1 and 540.2 per 100k Pt-Yrs (measured as TST >5, TST>10mm, QFT) https://t.co/SIkefJg909
6. A study of 27,959 acute coronary syndrome patients shows that the 46% with hyperuricemia (SUA > 6.0) had significantly greaters risks of cardiovascular events, regardless of a diagnosis of gout. https://t.co/chEJ8QeFh0
7. Outcomes of Systemic Sclerosis Hospitalization  
8. IL-12 and IL-23 Promote Giant Cell Arteritis  
9. 1st Ceremonial Burial of Dead Words in Rheumatology - The Rheumatology Dead Word Cemetary (CTD, Rheumatism, CREST, MCTD, and more) https://t.co/k3f5HgCCiQ 
10. Adult, Acute, Asymmetric Oligoarticular inflammatory arthritis - Whats your differential Dx? PsA, Spa, Reactive, IBD, Sarcoid, undifferentiated arthritis, CPPD, RA, chlamydia, Lyme, Fungal/Tbc, acute gonococcal infection.