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Inflammatory Conditions Up the Risk of Premature Myocardial Infarction

Mar 31, 2021 5:23 pm

The European Journal of Preventive Cardiology reports that younger patients with their first myocardial infarction before age 50 yrs have a higher risk of having a systemic inflammatory disease (SIDs) and higher rates all-cause mortality.

Data derived from the retrospective analysis of the YOUNG-MI registry that includes patients with their first MI at 50 years of age or younger. SIDs include patients with psoriasis, lupus or rheumatoid arthritis.

The young MI cohort consisted of 2097 patients and 53 (2.5%) had a SID. These were more likely females (36% vs. 19%, P = 0.004) with hypertension (62% vs. 46%, P = 0.025).

Young SID patients showed a higher risk of all-cause mortality (HR = 1.95, 1.07–3.57, P = 0.030),

This study suggest that an SID diagnosis is associated with worse long-term survival after premature MI.

The author has no conflicts of interest to disclose related to this subject

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