Worldwide Trends in Hyperuricemia Save
A Lancet Rheumatology systematic review shows the prevalence of hyperuricaemia has risen markedly over the past two decades in both men and women, owing to population growth, aging, and increasing age-specific rates
This review sought data on hyperuricaemia prevalence between 2000 and 2025 and included 402 reports (420 studies) and 7, 488, 451 adults in 34 countries.
The global prevalence of hyperuricaemia increased betweeb 2000 and 2023:
- from 6.7% to 11.2% in women
- from 12.3% to 18.6% in men
Prevalence of hyperuricemia rose
- from 126 million to 305 million in women
- from 226 million to 500 million in men
The authors estimated that population growth and ageing accounts for roughly half the increase. Prevalence was consistently higher in high-income and urban settings, and increased with age in both men and women, with sex differences narrowing in older age groups. Prevalence increased in nearly all countries.
Hyperuricaemia needs to be integrated into non-communicable disease surveillance systems and to implement targeted prevention and early management strategies to mitigate the associated metabolic and cardiovascular complications.
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