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Nutrition/Obesity

Proinflammatory Diet Increases Gout Risk

MedPage Today

Some dietary habits are worse than others when it comes to gout risk for women, a large study indicated.

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NHANES survey data on 2200 #RA pts shows dietary modification can yield reduced all-cause mortality risk. Diets w/ high Healthy Eating Index & low Dietary Inflammatory Index (DII) reduced mortality (HR 0.70; 95% CI: 0.53–0.92; adjusted P = 0.01) https://t.co/T77YQMvRQ2 https://t.co/WaCapITHGK
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Metanalysis of 11 studies shows that curcumin (tumeric) can reduce pain, muscle damage and inflammation in athletes following vigorous physical exercise. "pre- and post-exercise curcumin consumption.. assoc w/ better outcomes in muscle recovery, pain & antioxidant capacity"… https://t.co/FZE2ugvvPK

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Weak Data (1.24.2025)

Dr. Jack Cush reviews the news and journal reports from RheumNow.com, and features Dr. Charity Dean, the Keynote speaker at RheumNow Live 2025, and why she is an inspiration.

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GLP-1 Agonists Alleviate Knee Osteoarthritis In October, the NEJM published a randomized clinical trial demonstrating the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1ra) in patients with obesity and knee osteoarthritis. https://t.co/jlYGDTTsYZ https://t.co/O23mN1CPVO
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Fallen Angels (1.17.2025)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com; and pays homage to colleagues who passed away in 2024.

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GLP-1 Agonists Alleviate Knee Osteoarthritis In October, the NEJM published a randomized clinical trial demonstrating the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1ra) in patients with obesity and knee osteoarthritis. https://t.co/3ETmyFWpWY https://t.co/wn1QDwKi3R
Dr. John Cush @RheumNow( View Tweet )
Online, lifestyle intervention program shown to have positive long-term effects in 264 patients w/ Inflam Arthritis, OA & FM , even after 2-yrs. Prg focused on nutrition, exercise, relaxation & sleep. Signif reductions in Wt, BMI, and PRO's (pain, Am stiff, fatigue)… https://t.co/vghObYPnvW https://t.co/ZSdFPWel57
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Alive in 2025 (1.10.2025)

Dr. Jack Cush brings in the new year with a review of the latest from RheumNow.com

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GLP-1 Agonists Alleviate Knee Osteoarthritis

In October, the NEJM published a randomized clinical trial demonstrating the efficacy of glucagon-like peptide-1 receptor agonists (GLP-1ra) in patients with obesity and knee osteoarthritis.

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Post hoc study of Hidradenitis suppurativa (HS) phase 3 study w/ 588 pts rx w/ either PBO or adalimumab. 79% had elevated CRP. High CRP assoc w/ more severe HS, higher BMI (34 vs 28; P < .001), & lower odds of ADA response (OR 0.53). Activity or Obesity? https://t.co/ZQzumtW2LV https://t.co/FWaQMyP2TT
Dr. John Cush @RheumNow( View Tweet )
nline, lifestyle intervention program shown to have positive long-term effects in 264 patients w/ Inflam Arthritis, OA & FM , even after 2-yrs. Prg focused on nutrition, exercise, relaxation & sleep. Signif reductions in Wt, BMI, and PRO's (pain, Am stiff, fatigue)… https://t.co/ImNzTZGLut https://t.co/rAn8llwnjP
Dr. John Cush @RheumNow( View Tweet )
Sedentary Behavior Increases the Risk of Gout NHANES national survey study shows that sedentary behavior is an independent risk factor for gout, especially in those without hyperuricemia. https://t.co/LDhK3iDnrS https://t.co/z6I6tRw9Fr
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Italian study of 458 #RA pts shows 16% (71)meeting the EULAR criteria for difficult 2 Rx RA ( D2T-RA); unrelated to age, gender, seropositivity. BUT D2T-RA was assoc w/ erosions (24% vs 11%), obesity (33% vs 19%) & FM (25% vs 10%) https://t.co/w5mliNkfBT https://t.co/m65jk62wmh
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Best of 2024: Mixed Long-term Effects of Calcium and Vitamin D in Postmenopausal Women https://t.co/RxI1zlZ9YR https://t.co/vhsLi6HQAS
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ICYMI: VITAL Info on Autoimmune Disease (2.9.2024)

Dr. Jack Cush reviews the journal reports from the past week on RheumNow.com. Highlights are summarized by three songs: "Stairway to Heaven", "You're No Good", and "How Long (has this been going on)".

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Sedentary Behavior Increases the Risk of Gout

NHANES national survey study shows that sedentary behavior is an independent risk factor for gout, especially in those without hyperuricemia. 

The increasing prevalence of

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Best of 2024: Eating for Rheumatoid Arthritis https://t.co/gtK3F6FdEB https://t.co/ILA6lSohh7
Dr. John Cush @RheumNow( View Tweet )
Best of 2024: Mixed Long-term Effects of Calcium and Vitamin D in Postmenopausal Women https://t.co/rFOW4OpZS7 https://t.co/A0EN8b9KYB
Dr. John Cush @RheumNow( View Tweet )
FDA has approved Eli Lilly’s GLP-1 drug Zepbound [tirzepatide] to treat moderate to severe obstructive sleep apnea in adults with obesity in combination with increased physical activity and a reduced-calorie diet.” https://t.co/rYiM6JzmDX https://t.co/hO6CgH9pVs
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Best of 2024: Eating for Rheumatoid Arthritis

The majority of practicing rheumatologists at RheumNow Live 2024 were unaware of the new ACR guidelines issued in 2022 regarding dietary and lifestyle recommendations for patients with Rheumatoid Arthritis. Dr. Monica Guma reviewed these guidelines during her lecture on the impact of diet

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Best of 2024: Mixed Long-term Effects of Calcium and Vitamin D in Postmenopausal Women

A follow-up analysis of a randomized clinical trial found that the use of calcium and vitamin D supplements among postmenopausal women was associated with decreased risk for cancer mortality, but increased risk for cardiovascular disease mortality. The analysis is published in Annals of

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Best of 2024: Consensus Statements on Vitamin D

The “Controversies in Vitamin D” International Conference has published their proceedings on vitamin D metabolism, assessment, actions, and supplementation. Interestingly, optimal levels of 25-hydroxy vitamin D (25(OH)D) are still being debated.

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U.S. Preventive Services Task Force (USPSTF) has recommended AGAINST use of vitamin D +/- Ca for the primary prevention of fractures (or falls) in postmenopausal women/men > 60 years of age. or older.https://t.co/1bUBqTVaX0 https://t.co/AXWxduVkOT
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54K Peptic Ulcers Annually (12.13.2024)

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com

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