Skip to main content

Labs/Biomarkers

Lihi Eder, MD, PhD, on a Pre-Diagnosis Period for Psoriatic Arthritis

Jun 02, 2020

Is there a prodromal phase in psoriatic arthritis (PsA)? And if there is, could this represent an opportunity for earlier diagnosis of PsA?



Lihi Eder, MD, PhD, is a physician-researcher with the University of Toronto Institute of Health Policy, Management and Evaluation. She served as

Read Article

TNR Grand Rounds - Cytokine Storm Syndromes

May 27, 2020

This week's Tuesday Nite Rheumatology featured Dr Randy Cron from the University of Alabama - Birmingham as he spoke and took questions on the immunology, immunopathogenesis and treatment of Cytokine Storm Syndrome, especially as they relate to COVID-19 and rheumatic disease patients. The

Read Article

CDC on Pediatric Multi-System Inflammatory Syndrome

May 14, 2020

The latest hazardous spinoff to the coronavirus infection is an inflammatory, Kawasaki-like syndrome unique to children or adolescents with COVID-19. Sporadic reports from around the globe of this severe pediatric COVID syndrome have littered the news with brief mentions and little detail.

Read Article

Kids' COVID-Linked Ailment Is Not Your Typical Kawasaki Disease

May 14, 2020

As data continue to emerge about a multi-system inflammatory disorder in children apparently connected to COVID-19, evidence is growing that this is not your typical Kawasaki disease.



In New York, up to 102 children have reportedly developed this inflammatory syndrome, and three

Read Article

TNR Grand Rounds - What does COVID-19 have to do with Lupus?

May 13, 2020

Last night's Tuesday Nite Rheumatology featured Dr. Joan Merrill (OMRF). In her lecture, "What does COVID-19 have to do with lupus?", she discusses the pathogenesis of lupus, and specifically thrombotic microangiopathy, complementopathies, catastrophic lupus syndrome and the potential overlap

Read Article

RheumNow Podcast – The Beat Goes On (5.8.20)

May 07, 2020

Dr. Jack Cush reviews the news and journal reports from the past week on RheumNow.com.

Read Article

TNR Grand Rounds: IL-6 in Health and Disease

May 06, 2020

Dr. Len Calabrese from the Cleveland Clinic delivers this week's Tuesday Nite Rheumatology Grand Rounds, entitled "IL-6 in Health and Disease: Where Rheumatology Meets COVID-19".

Dr. Calabrese provides a comprehensive review of IL-6 biology, and discusses IL-6 signaling, IL-6 roles in health,

Read Article

Cigarette Smoking and ANCA-Associated Vasculitis

May 05, 2020

JAMA Internal Medicine has reported that cigarette smoking associated with an increased odds of having antineutrophil cytoplasmic antibody–associated vasculitis (AAV) (especially MPO positive AAV) and is thereby a modifiable risk factor for AAV.

In a case-control study, 473 AAV

Read Article

German Society of Rheumatology COVID Pandemic Recommendations

Apr 30, 2020

The Annals of Rheumatic Disease has published the preliminary recommendations of the German Society of Rheumatology for the management of Inflammatory rheumatic diseases patients during the SARS-CoV-2/Covid-19 pandemic.

These preliminary recommendations are based on an expert consensus from 17

Read Article

IL-6 Inhibitors May Benefit COVID-19 Infection

Apr 28, 2020

In the last few days there have been encouraging "preliminary" reports that IL-6 inhibition by either tocilizumab or sarilumab may be efficacious in patients with severe coronavirus infections.

Read Article

RheumNow Podcast – In Times of Trouble (4.24.20)

Apr 24, 2020

Dr Jack Cush reviews the news, journal reports, twitter feed and COVID developments from the past week on RheumNow.com

Read Article

Potential Role of B Cells in COVID

Apr 23, 2020

A pre-proof letter to the editor in the Journal of Allergy and Clinical Immunology presents a series of patients with immunoglobulin deficiency disorders and how they differentially responded when infected with the coronavirus.

They identified seven Primary Antibody Deficiencies patients with

Read Article

TNR Grand Rounds - Moving Forward with Telemedicine

Apr 22, 2020

Dr. Alvin Wells gives a primer on Telerheumatology and Telemedicine in the era of COVID-19. This 1 hour Grand Rounds Presentation includes a 30 minute lecture, followed by stimulating 30 minutes of Q&A with a rheumatology attendee audience.

Read Article

COVID-19 and the Slippery Road of Cytokine Storms

Apr 21, 2020

Early reports on the COVID-19 pandemic allude to a cytokine storm or hyper-inflammation, especially in patients who succumbed to the illness. These conclusions are based on elevated levels of ferritin and other inflammatory markers, drawing comparisons to rare diseases of uncontrolled

Read Article

A Role for Netosis in COVID-19 Infection?

Apr 20, 2020

Journal of Experimental Medicine has published a paper from a consortium of researchers at Cold Spring Harbor Laboratory, the Feinstein Institutes for Medical Research, and the Research Institute of the McGill University Health Centre (RI-MUHC) on the potential of neutrophil

Read Article

Tuesday Nite Rheumatology Grand Rounds - Febrile Disorders

Apr 17, 2020

Dr. Jack Cush reviews the appproach to evaluating fever in adults suspected of having a rheumatic disease, Stills disease or autoinflammatory conditions. Presentations, fever duration, disease criteria and genetic testing are discussed.

For more information on this subject or use of

Read Article

COVID-19 Systemic Involvement

Apr 15, 2020

The presentations of the COVID-19 infection have been clearly chronicled with the worrisome onset of sore throat, dry cough, loss of smell and taste with fevers, myalgias, fatigue and the worrisome progression of pulmonary involvement in a minority.  Lab findings may include a leukocytosis,

Read Article

ACR COVID-19 Guidance for Rheumatic Disease Patients

Apr 14, 2020

On April 11th, the ACR Board of Directors approved a COVID-19 guidance document written by an ACR task force charged with updating and clarifying recommendations for rheumatologists and rheumatic disease patient management during the current COVID-19 crisis.

This ACR release, in its

Read Article

RheumNow Podcast – The Beginning of Something Else (4.10.20)

Apr 10, 2020

Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com

Read Article

Coagulopathy and Antiphospholipid Antibodies with Covid-19

Apr 10, 2020

The New England Journal of Medicine has featured a report of three COVID infected patients, who developed peripheral and central infarcts with a antiphospholipid antibodies. 

All patients, who were hospitalized in Wuhan, China, had severe acute respiratory syndrome coronavirus 2 (SARS-

Read Article

TNR - Grand Rounds: Safety of Biologics & New Agents

Apr 08, 2020

On Tuesday, April 7th, RheumNow hosted its first Tuesday Nite Rheumatology webinar - kicking off a two-month series of Rheumatology Grand Rounds lectures.  The first session featured Jack Cush, MD (UT Southwestern) who lectured on "The Safety of Biologics and Newer Agents".

This 30

Read Article

Incubation Period for COVID-19

Apr 08, 2020

The incubation period for coronavirus disease 2019 (COVID-19) has important implications for surveillance and control activities. The Annals of Internal Medicine reports a pooled analysis of confirmed COVID-19 cases January 4, 2020 and February 24, 2020. The analyzed confirmed SARS-CoV-2

Read Article

NICE Guidelines on Managing Rheumatologic Conditions During COVID-19 Pandemic

Apr 07, 2020

On April 3rd, the National Institute for Health and Care Excellence (NICE) in the UK, published a rapid guideline for managing children and adults with rheumatological autoimmune, inflammatory and metabolic bone disorders during the COVID-19 pandemic, while protecting staff from infection.

Read Article

RheumNow Podcast – New World Order (3.27.20)

Mar 27, 2020

Dr. Jack Cush reviews the news and COVID developments from this past week.

Read Article
×