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45 yr adult male w/ Kawasaki-like multisystem inflammatory syndrome w/ COVID-19 infx: presented w/ 6d fever, sore throat, diarrhea, LN, BLE pain, conjunctivitis, tachycardia, ESR 120, CRP 546 mg/L, high Troponin; Rx and resolved w/ IVIG & TCZ https://t.co/cy

Dr. John Cush RheumNow ( View Tweet)

Jul 21, 2020
African-Americans with Ank Spondylitis have worse disease compared to whites. Study of 10,990 AS patients shows AA to have high frequency of anterior uveitis, hypertension, diabetes, depression, and heart disease and higher ESR and CRP levels.

Dr. John Cush RheumNow ( View Tweet)

Jul 08, 2020

ICYMI: The Nine Lives of Hydroxychloroquine (Updated)

Hydroxychloroquine is one of many medications frequently used in rheumatology practice. Its remarkable versatility is attested by its routine use in lupus, in patients with an autoimmune coagulopathy, in patients with rheumatoid arthritis, as well as in those with a low-level inflammatory

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Tocilizumab may be effective in refractory ocular-, neuro-, vasculo-Behcet's.

Dr. John Cush RheumNow ( View Tweet)

Jun 24, 2020
New genome wide association study on anterior uveitis. Heritability for uveitis is 0.7, much greater than axSpA.
Dr Philip Robinson philipcrobinson ( View Tweet)
Jun 07, 2020
#EULAR2020 OP0333: Could SLE itself be a risk factor for retinopathy (not just because of HCQ)? @Janetbirdope study of >600 pts noted retinopathy risk factors: 1. longer duration of antimalarials 2. any use of chloroquine 3.
Jun 07, 2020
This Spanish study of 255 SpA pts found that acute unilateral anterior uveitis was the most common pattern, primarily in HLA B27+. NO difference in incidence between SEC and TNFi treated pts. #EULAR2020 @RheumNow Poster #THU0388 https://t.co/OMfG8atfE4
Dr. Rachel Tate uptoTate ( View Tweet)
Jun 05, 2020
Our study shows that HCQ retinopathy virtually never occurs in first 5 yrs, SLE has more risk than other diseases such as RA and chloroquine has a far higher risk of retinal toxicity OP0333 #EULAR2020 @RheumNow @CRASCRRheum @earlyarthritis https://t.co/ZzRy3po4yw

Janet Pope Janetbirdope ( View Tweet)

Jun 05, 2020

Hydroxychloroquine Improves Survival in Lupus

May 26, 2020

Hydroxychloroquine (HCQ) has dominated the news in recent weeks, because of poor outcomes reported when used in COVID patients. Yet, a recent report reaffirms what rheumatologists have known for years - that HCQ use is associated with better outcomes in systemic lupus erythematosus, including

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Again, Antimalarial Use Fails to Benefit COVID

May 22, 2020

Today Lancet reported the results of another retrospective trial showing that hydroxychloroquine or chloroquine, alone or with a macrolide antibioitic, offered no additional benefits to COVID-19 patients, but was associated with higher rates of mortality and arrhythmia.



Analysis of a

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The Nine Lives of Hydroxychloroquine (Updated)

Hydroxychloroquine is one of many medications frequently used in rheumatology practice. Its remarkable versatility is attested by its routine use in lupus, in patients with an autoimmune coagulopathy, in patients with rheumatoid arthritis, as well as in those with a low-level inflammatory

Read Article

RheumNow Podcast - Despite Corona (3.6.20)

Mar 06, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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RheumNow Podcast - RWCS Quick Hits (2.14.20)

Feb 14, 2020

Dr. Jack Cush reviews the highlights from the 2020 RWCS meeting in Maui, Hawaii.

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Apremilast Reduces Oral Ulcers in Behcet's Syndrome

Dec 02, 2019

A multinational trial finds a statistically significant number of patients with Behçet's syndrome showed a greater reduction in the number of oral ulcers with apremilast compared with placebo.

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Hydroxychloroquine Blood Levels May Predict Future Retinopathy

Oct 14, 2019

A study of 527 patients receiving daily hydroxychloroquine (HCQ) concluded that hydroxychloroquine blood levels may predict future HCQ retinopathy.

This study assessed whether lower HCQ dosing, as recommended by the 2016 American Academy of Ophthalmology (AAO) guidelines (less than 5 mg

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ACR 2018 - Day 1 Report

Oct 11, 2019

Highlights from Tuesday and Wednesday (days 3 and 4) from the ACR annual meeting include: the important and impactful abstracts covered by the Rheumatology Roundup session; upadacitinib clinical trials; and the baricitinib CV and VTE safety analysis.

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RheumNow Podcast – Believe in Vitamin D or Rituximab? (9.20.19)

Sep 20, 2019

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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Steroid Sparing Effects of Methotrexate and Mycophenolate in Uveitis

Sep 11, 2019

Patients with noninfectious uveitis (intermediate, posterior uveitis, or panuveitis) often require high dose corticosteroids and therefore may need steroid-sparing DMARD therapy. The FAST study investigated the corticosteroid-sparing effect of methotrexate or mycophenolate mofetil in adults with

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Blinded by the Use of Antimalarials in Lupus?

Editor's note: July 1 - 5, RheumNow is running the best of EULAR 2019 meeting. Hydroxychloroquine (HCQ) will decrease SLE flares improve lipids, decrease clots, improve survival, augment the response to mycophenolate and are the cornerstone of treatment as per the SLE EULAR

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Blinded by the Use of Antimalarials in Lupus?

Hydroxychloroquine (HCQ) will decrease SLE flares improve lipids, decrease clots, improve survival, augment the response to mycophenolate and are the cornerstone of treatment as per the SLE EULAR guidelines presented at EULAR 2019 in Madrid and also published in ARD. But, if you

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Dermatology Guidelines for Psoriatic Comorbidities

Mar 04, 2019

The JAAD has published joint guidelines from the American Academy of Dermatology (AAD) and National Psoriasis Foundation (NPF) on the approach, management and dermatolgist roles for select comorbid conditions. 

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Best of 2018: Hydroxychloroquine Being Over-Dosed with New Guidelines?

Dec 28, 2018

Hydroxychloroquine retinopathy prevention guidelines have revised from ideal body weight-based dosing to actual body weight-based dosing; the question remains whether these have been adopted in clinical practice.

A database of nearly 21,000 new HCQ users from a UK general population database

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RheumNow Week in Review – Vitamin D Falls Again (10.4.18)

Oct 05, 2018

Dr. Jack Cush reviews the news from the past week on RheumNow.com. 

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Predictive Risk Factors for Uveitis in JIA

Oct 04, 2018

Researchers from Germany have studied a large cohort of juvenile idiopathic arthritis (JIA) patients and shown that JIA disease activity scores and laboratory biomarkers could be used to better define the group of JIA patients at high risk of uveitis onset.

They studied 964 JIA kids

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Hydroxychloroquine Being Over-Dosed with New Guidelines?

Jul 09, 2018

Hydroxychloroquine retinopathy prevention guidelines have revised from ideal body weight-based dosing to actual body weight-based dosing; the question remains whether these have been adopted in clinical practice.

A database of nearly 21,000 new HCQ users from a UK general population database

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