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Hydroxychloroquine Improves Survival in Lupus

May 26, 2020

Hydroxychloroquine (HCQ) has dominated the news in recent weeks, because of poor outcomes reported when used in COVID patients. Yet, a recent report reaffirms what rheumatologists have known for years - that HCQ use is associated with better outcomes in systemic lupus erythematosus, including

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Again, Antimalarial Use Fails to Benefit COVID

May 22, 2020

Today Lancet reported the results of another retrospective trial showing that hydroxychloroquine or chloroquine, alone or with a macrolide antibioitic, offered no additional benefits to COVID-19 patients, but was associated with higher rates of mortality and arrhythmia.



Analysis of a

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The Nine Lives of Hydroxychloroquine (Updated)

May 18, 2020

Hydroxychloroquine is one of many medications frequently used in rheumatology practice. Its remarkable versatility is attested by its routine use in lupus, in patients with an autoimmune coagulopathy, in patients with rheumatoid arthritis, as well as in those with a low-level inflammatory

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RheumNow Podcast - Despite Corona (3.6.20)

Mar 06, 2020

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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RheumNow Podcast - RWCS Quick Hits (2.14.20)

Feb 14, 2020

Dr. Jack Cush reviews the highlights from the 2020 RWCS meeting in Maui, Hawaii.

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Apremilast Reduces Oral Ulcers in Behcet's Syndrome

Dec 02, 2019

A multinational trial finds a statistically significant number of patients with Behçet's syndrome showed a greater reduction in the number of oral ulcers with apremilast compared with placebo.

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Hydroxychloroquine Blood Levels May Predict Future Retinopathy

Oct 14, 2019

A study of 527 patients receiving daily hydroxychloroquine (HCQ) concluded that hydroxychloroquine blood levels may predict future HCQ retinopathy.

This study assessed whether lower HCQ dosing, as recommended by the 2016 American Academy of Ophthalmology (AAO) guidelines (less than 5 mg

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ACR 2018 - Day 1 Report

Oct 11, 2019

Highlights from Tuesday and Wednesday (days 3 and 4) from the ACR annual meeting include: the important and impactful abstracts covered by the Rheumatology Roundup session; upadacitinib clinical trials; and the baricitinib CV and VTE safety analysis.

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RheumNow Podcast – Believe in Vitamin D or Rituximab? (9.20.19)

Sep 20, 2019

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

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Steroid Sparing Effects of Methotrexate and Mycophenolate in Uveitis

Sep 11, 2019

Patients with noninfectious uveitis (intermediate, posterior uveitis, or panuveitis) often require high dose corticosteroids and therefore may need steroid-sparing DMARD therapy. The FAST study investigated the corticosteroid-sparing effect of methotrexate or mycophenolate mofetil in adults with

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Blinded by the Use of Antimalarials in Lupus?

Editor's note: July 1 - 5, RheumNow is running the best of EULAR 2019 meeting. Hydroxychloroquine (HCQ) will decrease SLE flares improve lipids, decrease clots, improve survival, augment the response to mycophenolate and are the cornerstone of treatment as per the SLE EULAR

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Blinded by the Use of Antimalarials in Lupus?

Hydroxychloroquine (HCQ) will decrease SLE flares improve lipids, decrease clots, improve survival, augment the response to mycophenolate and are the cornerstone of treatment as per the SLE EULAR guidelines presented at EULAR 2019 in Madrid and also published in ARD. But, if you

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Dermatology Guidelines for Psoriatic Comorbidities

Mar 04, 2019

The JAAD has published joint guidelines from the American Academy of Dermatology (AAD) and National Psoriasis Foundation (NPF) on the approach, management and dermatolgist roles for select comorbid conditions. 

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Best of 2018: Hydroxychloroquine Being Over-Dosed with New Guidelines?

Dec 28, 2018

Hydroxychloroquine retinopathy prevention guidelines have revised from ideal body weight-based dosing to actual body weight-based dosing; the question remains whether these have been adopted in clinical practice.

A database of nearly 21,000 new HCQ users from a UK general population database

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RheumNow Week in Review – Vitamin D Falls Again (10.4.18)

Oct 05, 2018

Dr. Jack Cush reviews the news from the past week on RheumNow.com. 

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Predictive Risk Factors for Uveitis in JIA

Oct 04, 2018

Researchers from Germany have studied a large cohort of juvenile idiopathic arthritis (JIA) patients and shown that JIA disease activity scores and laboratory biomarkers could be used to better define the group of JIA patients at high risk of uveitis onset.

They studied 964 JIA kids

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Hydroxychloroquine Being Over-Dosed with New Guidelines?

Jul 09, 2018

Hydroxychloroquine retinopathy prevention guidelines have revised from ideal body weight-based dosing to actual body weight-based dosing; the question remains whether these have been adopted in clinical practice.

A database of nearly 21,000 new HCQ users from a UK general population database

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Best of 2017: New EULAR Guidelines on Behçet's

Jul 02, 2018

At the EULAR 2016 meeting, new EULAR recommendations for the management of Behçet's disease (BD) were presented. These were developed by a multidisciplinary expert committee that reviewed the evidence from the medical literature and developed final set of 9 recommendations:

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Canada Closer to Marijuana Approval

Jun 08, 2018

Reuters reports that Canada’s Senate on Thursday voted to legalize recreational marijuana, clearing a major hurdle that puts the country on track to become the first Group of Seven nation to permit national use of the drug.

Now the law and amendments go to the House of Commons who will

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Fish Oil Fails in Dry Eye Trial

May 03, 2018

Many topical and OTC products are recommended when treating chronic dry eyes, including omega-3 fatty acids (fish oil or n−3 fatty acids) to relieve symptoms; the NEJM reports that the DREAM trial shows no clinical benefit of n−3 fatty acids for 12 months when compared to placebo.

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Uveitis in JIA: Screen All, Treat Early

Apr 06, 2018

A European group of experts has formulated consensus-based recommendations for the treatment of juvenile idiopathic arthritis (JIA)-associated uveitis, focusing on screening, monitoring, and treatment of this potentially devastating extra-articular manifestation of JIA.

JIA-associated

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The RWCS - RheumNow Week in Review - 9 February 2018

Feb 09, 2018

Dr. Jack Cush reviews highlights, news and recent research published this week on RheumNow.com. This week's report includes news and education from the RWCS meeting in Maui. Also featured are uricase treatments for gout, exercise in RA, CVD in lupus, NFC predicting mortality in systemic

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Recurrent Uveitis Increases the Risk of Ankylosing Spondylitis

Feb 08, 2018

Arthritis Research and Therapy reports on the epidemiologic association between recurrent anterior uveitis and ankylosing spondylitis (AS) noting that as the number of uveitis episodes increases, so does the incidence of AS.

Uveitis is the most common extra-articular

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The RheumNow Week in Review - 2 February 2018

Feb 02, 2018

Dr. Jack Cush reviews highlights, news and recent research published this week on RheumNow.com. This week's report includes rising epidemiologic numbers, vaccine updates for H. Zoster and influenza, narcotics in spondylitis, overuse of OTC NSAIDs, problems with ILD in systemic sclerosis and

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The Red Eye in the Rheumatology Patient

Professor Rosenbaum is well known for his expertise in rheumatic eye disease and he gave a great summary of how to approach your patient having a red eye.The differential diagnosis for the red eye includes conjunctivitis, keratitis, acute anterior uveitis, episcleritis, scleritis

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