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Scleroderma/Raynauds

Machine learning to model risk for SSc-ILD ⭐️predict time to lung function decline ⭐️needs larger sample size Abs#OP0150 #EULAR2021 @RheumNow

Robert B Chao, MD @doctorRBC( View Tweet )

Jun 03, 2021
Positive RCT of Rituximab in Systemic sclerosis https://t.co/WsDZeollu0

Richard Conway @RichardPAConway( View Tweet )

Jun 02, 2021

RheumNow Podcast – Myth Busters (5.21.2021)

May 21, 2021

Dr Jack Cush reviews the news and journal reports from the past week on RheumNow.com




  1. Metanalysis (11 RCTs, 19 registries) of Pulm arterial HTN assoc. w/ CTD (w/ 1,267 & 4,008 CTD-PAH pts), showed Investigational Rxs reduced morbidity/mortality by 36%. CTD-PAH survival

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RheumNow Podcast – BandAids for Rheumatologists (5.14.2021)

May 14, 2021

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com - a website for rheumatologists, by rheumatologists.



We love Rheumatology!




  1. CDC study from 33 sites, 25 states showed vaccine efficacy (against Sx COVID) in HCP was 82% with ONEdose

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Tofacitinib in Ankylosing Spondylitis

Apr 28, 2021

A phase III trial assessing the efficacy and safety of tofacitinib in adults with with active ankylosing spondylitis (AS) shows that JAK inhibitiion was superior to placebo in a 48 week study.



A total of 269 adult AS patients with a prior an inadequate response or intolerance to ≥2

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Raynaud and Microvascular Complications with New Migraine Meds

Apr 20, 2021

A new study of calcitonin gene-related peptide (CGRP) antagonists for migraine headaches found that a small subset manifested Raynaud phenomenon and other had microvascular complications, suggesting that CGRP antagonists should be used in caution in patients with Raynauds. 

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RheumNow Podcast – Mistakes with Steroids

Apr 08, 2021

Dr Jack Cush gives his spin on this week's RheumNews and Rheum Research from RheumNow.com.

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News Feature: Rituximab in Systemic Sclerosis? A recent metanalysis suggests that rituximab may improve skin score and disease activity indices (DAS, mRSS) while stabilizing organ involvement in SSc patients. https://t.co/lH7aP7ht10 https://t.co/UdV8NRHxdC
Dr. John Cush @RheumNow( View Tweet )
Apr 07, 2021
News Feature: Actemra FDA Approved for Systemic Sclerosis Interstitial Lung Disease https://t.co/6A4muejeH9 https://t.co/D3JSfBpRZx
Dr. John Cush @RheumNow( View Tweet )
Mar 14, 2021

Actemra FDA Approved for Systemic Sclerosis Interstitial Lung Disease

Mar 08, 2021

Genentech announced Thursday that the US Food and Drug Administration approved tocilizumab (Actemra) for the treatment of Systemic Sclerosis-associated Interstitial Lung Disease (SSc-ILD), specifically indicated for slowing the rate of decline in pulmonary function in adults SSc-ILD.

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News Feature: Actemra FDA Approved for Systemic Sclerosis Interstitial Lung Disease https://t.co/6A4muejeH9 https://t.co/xQbIoEEscv
Dr. John Cush @RheumNow( View Tweet )
Mar 07, 2021

RheumNow Podcast – Pounds of Prevention (3.5.2021)

Mar 04, 2021

Dr. Jack Cush reviews and discusses nearly a dozen news reports and journal articles from the past week on RheumNow.com.

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QD Clinic: PFAPA Syndrome Recurrent Fevers, Stomatitis, Lymphadenopathy ? https://t.co/uMBk8e2wJO https://t.co/02ZMjRmOuU
Dr. John Cush @RheumNow( View Tweet )
Mar 01, 2021
Systemic Sclerosis is 5 times more prevalent in women than men. Analysis of epidemiology studies shows SSc prevalence as 17.6 per 100000 and pooled incidence of SSc was 1.4 per 100000 PYs. https://t.co/RyVIBUWyen

Dr. John Cush @RheumNow( View Tweet )

Mar 01, 2021

RheumNow Podcast – Sweet Lies or Hard Truths? (2.26.2021)

Feb 26, 2021

Dr. Jack Cush reviews and discusses the news and Journal reports from the past week on RheumNow.com.

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A woman w/ Raynauds, puffy fingers, nailfold capillary changes, abundant mat telangiectases consistent with limited cutaneous systemic sclerosis. Telangiectasias can be on skin, oral mucosa, GI tract & may associate w/ pulm HTN. https://t.co/FcL4VHMpmM

Dr. John Cush @RheumNow( View Tweet )

Feb 25, 2021
New Video: Dry Eyes and Tripping Over Tires RWCS 2021 Poster Session by Dr. Faizan Ahmad https://t.co/9UymYbYcJ0

Dr. John Cush @RheumNow( View Tweet )

Feb 24, 2021

Lung Preservation with Tocilizumab in Early Systemic Sclerosis

Feb 21, 2021

Arthritis & Rheumatology has published the results of a subanalysis from tocilizumab (TCZ) clinical trials showing that Il-6 inhibition was associated with preservation of lung function patients with early systemic sclerosis (SSc).

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RheumNow Podcast is now up! Systemic Sclerosis Pearls Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on https://t.co/fxtCOkxTER, https://t.co/nKRmKWR0Bd https://t.co/ESdycxLoCz
Dr. John Cush @RheumNow( View Tweet )
Feb 20, 2021

RheumNow Podcast – Systemic Sclerosis Pearls (2.19.2021)

Feb 18, 2021

Dr. Jack Cush reviews nearly a dozen news and journal reports from the past 2 weeks on RheumNow.com, including the ACR's new COVID-19 vaccine guidance for patients with rheumatic disease.

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Study of Systemic Sclerosis patients from the EUSTAR database: shows of the 144 with anti-PM/Scl+ Abs, there was an increased risk of muscle involvement, ILD, calcinosis and dermatomyositis; muscle involvement had a more severe disease phenotype. https://t.co/ORA2y1BWgn

Dr. John Cush @RheumNow( View Tweet )

Feb 15, 2021
Dry Eyes and Tripping Over Tires RWCS 2021 Poster Session by Dr. Faizan Ahmad https://t.co/9UymYbYcJ0

Dr. John Cush @RheumNow( View Tweet )

Feb 13, 2021
Systemic Sclerosis Rapid Onset Pulmonary Arterial Hypertension Pulmonary Capillary Hemangiomatosis RWCS 2021 Poster Session by Dr. Jason Melehani, Stanford University https://t.co/wfxiY2VqcN

Dr. John Cush @RheumNow( View Tweet )

Feb 12, 2021
Johns Hopkins & UCSF Scleroderma pts tested for Abs against telomerase & shelterin (TERF1); while rare in RA, myositis, controls; TERF1 Abs seen in 9% of SSc & assoc w/ severe lung disease (OR 2.4) & shorter telomere length. (TERF1 found in 7% of IPF) https://t.co/e5ai8uO4kK

Dr. John Cush @RheumNow( View Tweet )

Feb 09, 2021

RheumNow Podcast – Rheumatology Burnout (1.29.2021)

Jan 28, 2021

Dr. Jack Cush reviews this past week's journal articles and news features on RheumNow.com. Colchicine, vaccine rollout, risk of RA in endometriosis patients, tREACH trial, lupus nephritis news, rheumatology burnout and more.

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