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Articles By Jack Cush, MD

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EULAR 2016 Drug Safety Report

The EULAR Annual European Congress of Rheumatology meeting was held in London from June 8-11, 2016 and was well attended by thousands. This year’s meeting had over 2,000 poster displays, and the EULAR 2016 Congress presented new recommendations on the management of rheumatoid arthritis, spondyloarthritis, and fibromyalgia.

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Steroid Use in Early Rheumatoid Arthritis Associated with Fractures

The impact of systemic glucocorticoid exposure on fracture risk among new-onset rheumatoid arthritis (RA) was studied using administrative claims data detailing the treatments and outcomes of 42,127 newly diagnosed RA patients (between 2005-2012).

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RheumNow Week in Review – 17 June 2016

Dr. Jack Cush reviews the news, reports and highlights from EULAR and the last 2 weeks from RheumNow.com.

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AMA Promotes Training in Telemedicine

Recognizing that formalized training in telemedicine is not widely offered to physicians-in-training, the American Medical Association (AMA) adopted policy during its Annual Meeting aimed at ensuring medical students and residents learn how to use telemedicine in clinical practice.

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European Registries Show No Melanoma Risk with Biologics

The combined analysis of 130,315 rheumatoid arthritis patients from 11 European registries did not reveal an association between invasive (malignant) melanoma and the use of biologic therapies.

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Arthritis and Suicide Linked with Childhood Adversities

Men and women with arthritis have nearly a two-fold higher prevalence of lifetime suicide attempts than those without arthritis, according to a recent study from the University of Toronto.

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Long-Acting Opioids Associated with Higher Mortality Risk

Prescription of long-acting opioids for chronic noncancer pain was associated with an increased risk of all-cause mortality, including deaths from causes other than overdose, compared with anticonvulsants or cyclic antidepressants, according to a study appearing in the June 14 issue of JAMA.

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Parathyroidectomy Improves and Bisphosphonates Worsen Fracture Risk in Primary Hyperparathyroidism

A retrospective observational study of over 6000 patients with primary hyperparathyroidism (PHPT), followed in the Kaiser-Permanente system, has shown a greater need for parathyroidectomy than was previously thought.

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U-ACT-Early and the Benefits of Tocilizumab

Lancet has published the results of the U-ACT-early study assessing the efficacy of monotherapy versus combination therapy using an interleukin-6 receptor-blocking monoclonal antibody, tocilizumab, in patients with rheumatoid arthritis.

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Ixekizumab Success with the UNCOVER Trials in Psoriasis

The NEJM today published the results of two phase-3 trials (UNCOVER-2 and UNCOVER-3) demonstrating the efficacy of ixekizumab (a monoclonal antibody against interleukin-17A) in the treatment of moderate-to-severe psoriasis.

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