QD Clinic Podcast - 106 thru 109

Save

Here is the last of our QD Clinics in Podcast form, just before we start ACR2020 coverage.

In this compilation from the past week we talk about

- HIV and arthritis

- Hyperuricemia in PsA

- An odd kind of dermatomyositis

RheumNow Podcast – ACR 20 is Coming to Town (10.30.20)

Save

Dr Jack Cush overviews the RheumNow commitment, upcoming bonus coverage of ACR20 and the good news and journal reports from the past week on RheumNow.com

Abatacept in Early Systemic Sclerosis (ASSET study)

Save

An open-label extension of the ASSET trial (abatacept in diffuse cutaneous systemic sclerosis) showed continued safety with significant improvements in the modified Rodnan Skin Score (mRSS) at 12 months, suggesting abatacept (ABA) may benefit early systemic sclerosis (SSc).

Immune Necrotizing Myopathy

Save

A full read review of immune-mediated necrotizing myopathy is portrayed as a distinct subtype of inflammatory myopathies first described in 2004.

RheumNow Podcast – Back Talk: Questions from Listeners (10.23.20)

Save

Dr. Jack Cush reviews the news, journal reports, survey results and "Back Talk" questions from Rheums.

ICI Arthritis Tied to Cancer Progression

Save

Cancer patients treated with immune checkpoint inhibitors (ICI) who develop severe arthritis may be at risk for progression of the malignancy, a single-center study suggested.

Biologics Beneficial in Eosinophilic Vasculitis

Save

Two biologic therapies showed promise in the treatment of refractory or relapsing eosinophilic granulomatosis with polyangiitis (EGPA) in a retrospective European study.

2020 Nobel Prize in Medicine Goes to the Discovery of Hepatitis C

Save

The Nobel Assembly at Karolinska Institutet has awarded the 2020 Nobel Prize in Physiology or Medicine jointly to Harvey J. Alter, Michael Houghton and Charles M. Rice for the discovery of Hepatitis C virus. These three scientists made a decisive contribution to the fight against blood-borne hepatitis C, a major global health problem that causes cirrhosis and liver cancer in people around the world.

RheumNow Podcast – Function Follows Form (10.2.20)

Save

Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com. Regulatory approvals, update on global rheumatology alliance, smoking and psoriasis, gabapentin let down and defining difficult RA.

Slow Lung Decline Typical in Systemic Sclerosis

Save

The interstitial lung disease that develops in a subset of patients with systemic sclerosis tends to be heterogeneous, with the majority of patients experiencing a slow pattern of decline in lung function, analysis of outcomes in the European Scleroderma Trials and Research (EUSTAR) database foun

Novel Biologic Promising in Mid-Stage Scleroderma Trial

Save

The anti-interleukin agent romilkimab showed significant benefits on skin fibrosis among patients with systemic sclerosis in a phase II trial, researchers reported.

RheumNow Podcast – Cardiovascular Risk in Psoriatic Disease (9.25.20)

Save

Dr. Jack Cush reviews the news and Journal articles from the past week on RheumNow.com.

Livedo, Purpura and Coagulopathy in Severe COVID-19

Save

JAMA Dermatology expands the spectrum of complications seen with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection describing cutaneous purpura and livedo lesions in patients with severe COVID-19.

Insights into Antinuclear Antibodies in Systemic Lupus Erythematosus

Save

Pisetsky and Lipsky have reviewed the evolving literature on the utility of antinuclear antibodies (ANA). ANAs generated as part of an autoimmune disorder may form immune complexes that mediate pathogenesis by tissue deposition or cytokine induction.

COVID and the Multisystem Inflammatory Syndrome in Children

Save

Lancet Infectious Disease has reviewed the epidemiology, causes, clinical features, and current treatment for the multisystem inflammatory syndrome in children (MIS-C) and adolescents associated with COVID-19, noting severe organ damage can occur pediatric COVID-19 patients who are severely ill.&

RheumNow Podcast – Rheum Lives Matter (8.28.20)

Save

Dr. Jack Cush reviews the news and journal articles from the past week. Of mice and men in cartilage, the efficacy of JAK inhibitors in patients who are having skin problems, nrAxSpa has its own diagnostic code, metformin, talking about Back Talk, plus so much more.

Hepatitis C Anti-Viral Drug-Induced Arthritis

Save

Curative direct-acting antiviral therapy (DAAT) for hepatitis-C virus (HCV) infection has been revolutionary, but a novel report shows that nearly one quarter of DAAT treated patients developed new onset or significant worsening of MSK symptoms, despite being negative for hepa

Treatments Differ Across Centers in Systemic JIA

Save

Significant variations were seen across hospitals in the treatment of children admitted with new-onset systemic juvenile idiopathic arthritis (JIA), despite increasing evidence of the efficacy of biologics and the hazards of extended glucocorticoid exposure, a retrospective cohort study found.

Update on Polymyalgia Rheumatica and Giant Cell Arteritis

Save

JAMA has published a clinical update of recent studies on GCA. While PET/CT scanning are novel means of demonstrating activity, they have not changed the diagnostic approach to GCA or PMR and although there are no new proven treatment strategies for PMR beyond glucocorticoids, the FDA has approved tocilizumab as a first-line glucocorticoid-sparing agent.