Good News from ACR17 - Gout

Jack Cush, MD

Nov 14, 2017 7:17 pm

The following is a collection of gout-specific mentions culled from RheumNow's coverage of the Annual ACR 2017 meeting in San Diego.

Visit our RheumNow annual meeting site to read our gout content - http://acr17.rheumnow.com/category/gout-crystal/

Specific items:

Treatment of hyperuricemia to prevent incident dementia? Some data suggests this. Abstract #2076
PossibleGout and OA connection? Human cartilage increases amount and size of MSU crystals. Abstract #2896 http://ow.ly/ABLg30fM2gw
Low Uric acid may raise the risk of dementia. Abstract #2080
Lower coffee consumption is associated with gout! Abstract #2066
Allopurinol and Febuxostat in lowes the risk of Dementia. Yes you read that right! Jas Singh et al. Abstract #2076
Both generic and environmental factors influence the fractional excretion of uric acid Abstract #2061
Hyperuricemia is associated with more rapid knee osteoarthritis progression. A&R 2017
Tollerizing pegloticase regimen decreases infusion reactions in the TRIPLE study Abstract #1141
Gout is under treated people… need to get better Abstract #1121
If you have gout and type II diabetes you have worse gout. More tophi and erosions. Abstract #1118
Uncontrolled gout is associated with more heart failure so treat gout effectively. Abstract #1119
Risk for CV events lower with the new start probenecid (rather than allopurinol) for older >65 yo patients Abstract #159
Dr. Daniel Solomon YR in Review – the DASH diet decrease gout risk https://doi.org/10.1136/bmj.j1794
Diuretics don’t seem to impact hugely on gout treatment objectives in this study Abstract #1129
Patients aren’t getting to urate target in gout when treated with allopurinol. Are we using enough? Abstract #166
Do we need to change the label ‘gout’ ?!?!? Has negative stereotypes Abstract #1107
Patients with gout have their XOI stopped when they present with AKI. Evidence free zone and makes gout Rx harder. Abstract #1116
Gout patients more likely to achieve sUA goal 6 mg/dL if managed by a rheumatologist. Go team Rheum! Abstract #166
Pre-Rx with methylprednisolone superior to HC as prophylaxis for pegloticase w/ greater drug survival Abstract #213 https://buff.ly/2hKNl3y
Double contour sign - earliest sign of uric acid deposition obs in asymptomatic gout pts. Abstract #250 http://ow.ly/YZtb30fDVzZ
US of MTP1, distal patellar/triceps tendons, talar + femoral cartilage for MSU in possible gout Abstract #249
FORTUNE1: stepwise Uloric dose comparable to colchicine+Uloric in flare prevention during introductory Rx
Cankinumab reduces CV events, decreases risk of gout & malignancy. Higher infection risk #YearInReview
“Gout patients can have septic arthritis and sickle cell pts can also have gout. Keep this in mind during your nex sickle cell crisis differential diagnoses.” – J Cush, MD (Rheumatology Roundup).