The RheumNow Week in Review – 24 March 2017 Save

Dr. Jack Cush reviews news and highlights from the past week on RheumNow.com.  

1. NEJM Lyrica (pregabalin) shown to be ineffective in RCT of acute/chronic sciatica pain. 209 pts, Lyrica=PBO, more AE w/ Lyrica http://buff.ly/2nZjwxE
2. Amgens Amjevita (biosimilar of Humira) was approved by EMA for EU use in adult/Peds arthritis IBD, SpA &  more http://buff.ly/2mzCAWi  
3. 4 center study of 23 HIV pts shows TNF inhibitors are not assoc w/ higher rates of serious infxn in HIV pts https://t.co/D9R0LByBIJ
4. Are you aware? Sunshine Act mandates reporting of MDs accepting journal reprint - ask your rep if your being "charged" $1 or $25! INCREDIBLE
5. H. Zoster vaccine confers significant 5yr protection in 59627 vaccinated IMID/AI pts; 44% less HZ yr 1; 23%less @5yr https://t.co/AkCHqCknyT
6. Color Doppler US in 79 SSc pts: CDUS findings assoc w/ Incr CRP, ⩾20 pk-yrs smoking, male, digital ulcers pulp scars https://t.co/TQad1rKyio
7. MTX-pancytopenia 46 Indian pts: Mean dose 10mg, Onset Sx=mucositis, fever; ^ risk w/ low ALB, renal failure; 13 dead https://t.co/728jJA9nix
8. AAOS meeting reports that smoking cessation prior to hip/knee Arthroplasty improves outcomes, lessens complications https://t.co/hBZ7cTBG0l
9. IBD may be a rare complication of systemic JIA treated with IL-1 inhibitors - 3/81 cases ID by retrospective review, GERmany, WELL, 4.3 yrs later https://t.co/EAa0xNrD69  
10. Systematic review of 1247 pts w/ knee OK & TKA < age 55 yrs - w/ 10.8yrs F/U; 85.5% satisfaction, 5.4% revision rate http://buff.ly/2mFXjTD
11. Rheumatic Manifestations Following Chikungunya Infection, RHUMAOCHIK study  
12. NEJM Reviews Psoriatic Arthritis  
13. Lupus Hepatitis and Lupoid Hepatitis Reviewed
14. Checkpoint Inhibitors Causing Rheumatic Disease
15. Sjogren's Syndrome Foundation's 2017 Sjogren's Treatment Guidelines