Surgery

RheumNow Podcast – Drive Them Crazy (4.17.20)

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Dr. Jack Cush reviews the news, journal articles and new ACR COVID-19 guidelines from the past week on RheumNow.com.

Rituximab in Rheumatoid Vasculitis

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The Journal of Rheumatology reports a retrospective, single center, analysis of 17 rheumatoid vasculitis patients who responded well to intravenous rituximab (RTX) therapy.

They identified 17 patients treated with RTX for systemic rheumatoid vasculitis from 2000 to 2017. At RV

Low Risk with Immunosuppression at Surgery

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The Annals of Rheumatic Disease reports that rheumatoid arthritis patients on biologic therapies do not have a greater risk of postoperative infection after hip fracture, abdominopelvic or cardiac surgery compared (compared with those on methotrexate alone) and that glucocorticoids were

Bariatric Surgery Improves Rheumatoid Activity

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Obesity is a risk factor for the onset of rheumatoid arthritis (RA) and may also an impediment to optimal DMARD and biologic responses.  A new study has shown that after 1 year, obese RA patients undergoing bariatric surgery with weight loss had significantly lower disease activity.

RheumNow Podcast - RWCS Quick Hits (2.14.20)

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Dr. Jack Cush reviews the highlights from the 2020 RWCS meeting in Maui, Hawaii.

Bariatric Weight Loss Fails to Alter RA Risk

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Obesity has been shown to be a risk factor for the onset of rheumatoid arthritis (RA) and also shown to affect outcomes by impairing responses to many DMARD therapies. A Swiss study of RA patients undergoing bariatric surgery failed to show that bariatric surgery and weight loss had any effect

Aspirin after Hip or Knee Arthoplasty

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JAMA Internal Medicine has reported that use of low dose aspirin for venous thromboembolism (VTE) prophylaxis after total hip and knee replacement is equal in efficacy to other anticoagulants.

Knee Replacements Last 25 Years

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UK registry reports that greater than 80% of total knee replacements can last for 25 years.

The outcomes regarding the duration and durability of knee arthroplasties is sketchy, with many orthopedists projecting a 15 to 20 year survivial. Hence the need for an appraisal of the data.

NSAIDs May Impair Healing if Taken Nightly

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A new study in Scientific Reports suggest that circadian rhythms play an important role in wound healing, and that nonsteroidal anti-inflammatory drugs (NSAIDs) may be disruptive if taken at night given primary healing that occurs in a body at night. 

NSAIDs provide analgesic

RheumNow Podcast- The Down Side of Steroids (1.17.20)

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Dr. Jack Cush reviews the journal reports and news from RheumNow.com.
Be sure to register for RheumNow Live 3/13/2020 in Fort Worth
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Best of 2019 - War on RA - Part 3: Useless Drugs

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We have options that are endless – we have 28 biologics in rheumatology; 19 approved for RA in the last 20 years, but 15 of these are me-too copies or biosimilars. We currently have 2 JAK inhibitors and may have 3 or 4 by year end. But what we really need is the right drug, at the right time,

Predicting Inpatient Gout Flares

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Analysis of New Zealand hospitalized patients revals nine predictors of inpatient flare for people with comorbid gout.

This retrospective cohort study of hospitalised patients with comorbid gout included 625 hospitalised patients, 87 experienced inpatient gout flare.

There were 9

RheumNow Podcast - The Elusive Hand OA Problem (12.13.19)

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Dr. Jack Cush recaps the news and journal reports from the past week on RheumNow.com.

One-Third of Psoriatic Arthritis Patients Will Need Joint Surgery

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Dannish study has shown that one-third of psoriatic arthritis (PsA) will have joint surgery that that PsA patients have twice the rate of joint surgery when compared with the general population.

The Danish National Patient Registry was used in this cohort study of incident PsA patients

ASBMR Recommendations on Secondary Fracture Prevention

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The American Society for Bone and Mineral Research has developed multistakeholder consensus clinical recommendations for the prevention of secondary fractures for those aged 65 years and older after an initial hip or vertebral fracture.

Overall they have promoted 13 recommendations (7

Similar Outcomes for Hip Arthroplasty or Hemiarthroplasty in Hip Fracture

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The NEJM reports on a randomized comparison of hemiarthroplasty and total hip arthroplasty in displaced femoral neck fractures and shows no difference in function and quality of life over 24 months.

This Canadian, multicenter trial included 1495 patients, over age 50 years, who had a

RheumNow Podcast – Believe in Vitamin D or Rituximab? (9.20.19)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

FEAR: A Perception of Fact In Spite of the Fiction

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Pregnancy for patients with lupus has long been considered high risk and associated with both medical and obstetric complications, but outcomes have improved over the last 2 decades and continue to improve. The large decline in in-hospital maternal mortality was greater for lupus pregnancies

RheumNow Podcast – The End of Arthritis (9.13.19)

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Dr. Jack Cush reviews the news and journal articles from the past week on RheumNow.com.

Need for Pre-operative Hyperglycemia Testing Prior to Total Joint Replacement

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JAMA reports on a large Medicare cohort study showing that amongst patients undergoing total joint replacement (TJR), preoperative HbA1c testing was performed in 26% to 43% of patients with diabetes and in only 5% of those without diabetes. Importantly research has shown that an elevated HbA1c

Weight Loss Cuts Hospital Stays for Obese TKA Patients

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Morbidly obese patients who lost 20 lbs before total knee arthroplasty (TKA) cut their hospital stays by about 1 day, and were 76% less likely to have an extended hospital stay, research showed. 

However, morbidly obese patients who lost between 5 and 10 lbs before the surgical

RheumNow Podcast – Antibiotics Increase RA Risk (8.16.19)

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Dr. Jack Cush reports the news and important journal articles from the past week on RheumNow.com.

War on RA - Part 3: Useless Drugs

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We have options that are endless – we have 28 biologics in rheumatology; 19 approved for RA in the last 20 years, but 15 of these are me-too copies or biosimilars. We currently have 2 JAK inhibitors and may have 3 or 4 by year end. But what we really need is the right drug, at the right time,

Joint Surgery Rates Remain High in Psoriatic Arthritis

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The incidence rate of joint surgery among patients with psoriatic arthritis (PsA) has remained persistently high, double that of the general population, according to a new Danish cohort study.

During the years 1996-2000, the incidence rate of joint surgery was 18.2 per 1,000 person-

Partial or Total Knee Replacement for Osteoarthritis?

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Lancet has reported on a clinical trial comparing total knee replacement (TKR) and partial knee replacement (PKR) in late-stage isolated medial compartment knee osteoarthritis patients finding that both TKR and PKR are equally effective, PKR should be considered the first, because of lower