Sildenafil May Help Heal Scleroderma Ulcers Save

A prospective study of sildenafil was conducted in 25 centers that included 83 patients and 192 digital ulcers at entry. The odds of healing ulcers was less, but not significant, for sildenafil.  Although the primary endpoint of the trial was not met, the mean number of digital ulcers was significantly lower at week 8 and 12 for those on sildenafil.