Skip to main content

Fatigue is Under-Appreciated in Psoriatic Arthritis

Aug 09, 2022 5:48 pm

Patient-reported fatigue is high in patients with psoriatic arthritis (PsA) and often goes under-recognized by physicians. Fatigue importantly impacts physical functioning, work productivity, and health related quality of life (HRQoL).

A cross-sectional survey of 831 physician-confirmed PsA patients (United States and Europe) was conducted in 2018. Fatigue was collected as a binary variable and its severity assessed using a 0-10 scale as part of the Psoriatic Arthritis Impact of Disease (PsAID) fatigue question). Other PROMs collected included EQ-5D-5L (HRQoL), HAQ-DI, and Work Productivity and Activity Impairment (WPAI). 

These PsA patients had a mean age 47.5 years, and mean disease duration 5.3 years. Roughly half were female and half were receiving a biologic.

Fatigue was reported by 78.3% of patients. Fatigue severity was associated with greater disease duration, PsA severity, pain levels, psoriasis BSA, and swollen and tender joint counts (all p<0.05).

Greater fatigue severity was significantly associated with worse physical functioning, HRQoL, and work productivity (all p<0.001).

Fatigue was under-reported by physicians - only 32% of those patients who self-reported fatigue.

While being under-recognized by physicians, fatigue has a pervasive effect on patient disease severity, physical functioning, work productivity, and HRQoL.

Disclosures
The author has no conflicts of interest to disclose related to this subject

Add new comment

If you are a health practitioner, you may to comment.

Due to the nature of these comment forums, only health practitioners are allowed to comment at this time.

×