Disappointment Behind Acute Gout Hospitalizations Save

Analysis of emergency department visits from two UK hospitals shows a high rate of hospitalization, and low use of urate-lowering therapies (ULT) and treat-to-target (T2T) management.
Between 2017 and 2020 there were 1,220 emergency attendances for gout flares - 23.5% required hospitalization (median length of stay: 3.6 days). Moreover, 10% of patients had recurrent ER visits attendances for gout flares.
Using multivariate logistic regression models, predictors of hospitalization from gout included:
- older age
- overnight ED arrival time
- higher serum urate
- higher CRP
- higher WBC at presentation
Caveats from this study:
- Only 22.6% of patients with pre-existing gout were receiving ULT at presentation.
- Rheumatology consultation and synovial aspirates were rarely obtained.
- Six months post-discharge, 44% were receiving ULT; but few had T2T optimization, with only 9.1% achieving a urate ≤360 micromol/L.
Gout management, at presentation, hospitalization and post discharge, remains woefully inadequate.
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